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Outputs (623)

Traditional healers working with primary care and mental health for early intervention in psychosis in young persons: protocol for the feasibility cluster randomised controlled trial (2023)
Journal Article
Farooq, S., Sheikh, S., Dikomitis, L., Haq, M. M. U., Khan, A. J., Sanauddin, N., …Lewis, M. (2023). Traditional healers working with primary care and mental health for early intervention in psychosis in young persons: protocol for the feasibility cluster randomised controlled trial. BMJ Open, 13(7), e072471. https://doi.org/10.1136/bmjopen-2023-072471

Objectives: In low/middle-income countries (LMICs), more than half of patients with first-episode psychosis initially seek treatment from traditional and religious healers as their first care. This contributes to an excessively long duration of untre... Read More about Traditional healers working with primary care and mental health for early intervention in psychosis in young persons: protocol for the feasibility cluster randomised controlled trial.

Protocol for the mixed methods, Managing young people (aged 16–25) with Attention deficit hyperactivity disorder in Primary care (MAP) study: mapping current practice and co-producing guidance to improve healthcare in an underserved population (2023)
Journal Article
Price, A., Smith, J. R., Mughal, F., Salimi, A., Melendez-Torres, G. J., & Newlove-Delgado, T. (2023). Protocol for the mixed methods, Managing young people (aged 16–25) with Attention deficit hyperactivity disorder in Primary care (MAP) study: mapping current practice and co-producing guidance to improve healthcare in an underserved population. BMJ Open, 13(7), Article e068184. https://doi.org/10.1136/bmjopen-2022-068184

Introduction: Attention deficit hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder in children and adolescents, with an average worldwide prevalence of 5%. Up to 40% of young people continue to experience symptoms into adult... Read More about Protocol for the mixed methods, Managing young people (aged 16–25) with Attention deficit hyperactivity disorder in Primary care (MAP) study: mapping current practice and co-producing guidance to improve healthcare in an underserved population.

Stratified primary care for adults with musculoskeletal pain: the STarT MSK research programme including RCTs (2023)
Report
E Foster, N., M Dunn, K., Protheroe, J., C Hill, J., Lewis, M., Saunders, B., …Chudyk, A. (2023). Stratified primary care for adults with musculoskeletal pain: the STarT MSK research programme including RCTs. NIHR

Background Usual primary care for patients with musculoskeletal pain varies widely and treatment outcomes are suboptimal. Stratified care involves targeting treatments according to patient subgroups, in the hope of maximising treatment benefit and re... Read More about Stratified primary care for adults with musculoskeletal pain: the STarT MSK research programme including RCTs.

Neural immune cell responses to clinically relevant ligands of the niacin receptor (Gpr109a): niacin and monomethyl fumarate (2023)
Thesis
Brown-Lyons, A. L. (2023). Neural immune cell responses to clinically relevant ligands of the niacin receptor (Gpr109a): niacin and monomethyl fumarate. (Thesis). Keele University

Background: Inflammation is a major driver, and perhaps cause, of neurodegeneration, suggesting neuroimmunomodulation as a therapeutic strategy. Microglia, the primary mediators of neuroinflammation, switch between three activation states [surveillan... Read More about Neural immune cell responses to clinically relevant ligands of the niacin receptor (Gpr109a): niacin and monomethyl fumarate.

The role of Endothelial Progenitor Cells in the pleiotropic effects of Atorvastatin (2023)
Thesis
Sandhu, K. S. (2023). The role of Endothelial Progenitor Cells in the pleiotropic effects of Atorvastatin. (Thesis). Keele University

The following thesis began by discussing current controversies surrounding EPC identification then studied the effect of atorvastatin on EPC numbers in bench and bed side studies. Atorvastatin was hypothesised to increase chemokine CXCL-12 its recep... Read More about The role of Endothelial Progenitor Cells in the pleiotropic effects of Atorvastatin.

Using Twitter to mobilise knowledge for First Contact Physiotherapists - A qualitative study (2023)
Thesis
Campbell, L. H. (2023). Using Twitter to mobilise knowledge for First Contact Physiotherapists - A qualitative study. (Thesis). Keele University

Background - First Contact Physiotherapists (FCPs) specialise in supporting people who consult with musculoskeletal conditions in National Health Service primary care. Cited FCP role challenges include professional isolation, time demands and changin... Read More about Using Twitter to mobilise knowledge for First Contact Physiotherapists - A qualitative study.

“Hot and bitter tears” (辛酸泪): An inquiry into Chinese migrants’ experiences of undocumented status (2023)
Thesis
Machin, H. E. (2023). “Hot and bitter tears” (辛酸泪): An inquiry into Chinese migrants’ experiences of undocumented status. (Thesis). Keele University

Undocumented Chinese migration to the UK has, in the aftermath of widely publicised events such as the Dover and Morecambe Bay tragedies, triggered significant concern. Since such events, attention has turned to other forms of irregular entry. Yet, u... Read More about “Hot and bitter tears” (辛酸泪): An inquiry into Chinese migrants’ experiences of undocumented status.

Statistical methods for prognostic factor and risk prediction research (2023)
Thesis
Whittle, R. L. (2023). Statistical methods for prognostic factor and risk prediction research. (Thesis). Keele University

Prognosis research is an important part of medical research as it seeks to understand, predict, and improve future outcomes in people with a given disease or health condition. This thesis focuses on the application and development of statistical meth... Read More about Statistical methods for prognostic factor and risk prediction research.

The management of varices in acute on chronic liver failure: a systematic review of guidelines and investigation of local practice (2023)
Thesis
Kesavan, S. (2023). The management of varices in acute on chronic liver failure: a systematic review of guidelines and investigation of local practice. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/515604

Varices are a complication of chronic liver disease and are associated with a high mortality if they haemorrhage. Patients need to be managed using the best available evidence to improve their outcomes. This thesis is formed of two parts: a systemati... Read More about The management of varices in acute on chronic liver failure: a systematic review of guidelines and investigation of local practice.