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Outputs (623)

Psychosocial factors affecting COVID-19 vaccine uptake in the UK: a prospective cohort study (CoVAccS – wave 3) (2023)
Journal Article
Smith, L., Sim, J., Cutts, M., Dasch, H., Amlôt, R., Sevdalis, N., …Sherman, S. (2023). Psychosocial factors affecting COVID-19 vaccine uptake in the UK: a prospective cohort study (CoVAccS – wave 3). https://doi.org/10.1016/j.jvacx.2023.100276

Background We investigated factors associated with COVID-19 vaccine uptake, future vaccination intentions, and changes in beliefs and attitudes over time. Methods Prospective cohort study. 1500 participants completed an online survey in January... Read More about Psychosocial factors affecting COVID-19 vaccine uptake in the UK: a prospective cohort study (CoVAccS – wave 3).

Association of Frailty Status on the Causes and Outcomes of Patients Admitted With Cardiovascular Disease. (2023)
Journal Article
Sokhal, B., Matetić, A., Rashid, M., Protheroe, J., Partington, R., Mallen, C., & Mamas, M. (2023). Association of Frailty Status on the Causes and Outcomes of Patients Admitted With Cardiovascular Disease. American Journal of Cardiology, 7 - 15. https://doi.org/10.1016/j.amjcard.2022.12.029

Data are limited about the contemporary association between frailty and the causes and outcomes of patients admitted with cardiovascular diseases (CVD). Using the US National Inpatient Sample, CVD admissions of interest (acute myocardial infarction,... Read More about Association of Frailty Status on the Causes and Outcomes of Patients Admitted With Cardiovascular Disease..

The experiences of remote consulting for people with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and fibromyalgia in primary care (2023)
Presentation / Conference
Leach, H., Atherton, H., Eccles, A., & Chew-Graham, C. (2023, March). The experiences of remote consulting for people with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and fibromyalgia in primary care. Presented at BJGP Research Conference 2023, London, England, UK

Background Restrictions due to the COVID-19 pandemic resulted in a sudden shift to a predominantly remote consulting model in primary care from March 2020. Little evidence exists examining the experience of remote consulting for people living with ch... Read More about The experiences of remote consulting for people with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and fibromyalgia in primary care.

Data from Combined Perioperative Lapatinib and Trastuzumab in Early HER2-Positive Breast Cancer Identifies Early Responders: Randomized UK EPHOS-B Trial Long-Term Results (2023)
Dataset
Bundred, N., Porta, N., Brunt, A. M., Cramer, A., Hanby, A., M. Shaaban, A., …Bliss, J. M. (2023). Data from Combined Perioperative Lapatinib and Trastuzumab in Early HER2-Positive Breast Cancer Identifies Early Responders: Randomized UK EPHOS-B Trial Long-Term Results. [Dataset]. https://doi.org/10.1158/1078-0432.c.6532623

Purpose: EPHOS-B aimed to determine whether perioperative anti-HER2 therapy inhibited proliferation and/or increased apoptosis in HER2-positive breast cancer. Patients and Methods: This randomized phase II, two-part, multicenter trial included n... Read More about Data from Combined Perioperative Lapatinib and Trastuzumab in Early HER2-Positive Breast Cancer Identifies Early Responders: Randomized UK EPHOS-B Trial Long-Term Results.

Data from Combined Perioperative Lapatinib and Trastuzumab in Early HER2-Positive Breast Cancer Identifies Early Responders: Randomized UK EPHOS-B Trial Long-Term Results (2023)
Dataset
Bundred, N., Porta, N., Brunt, A. M., Cramer, A., Hanby, A., Shaaban, A. M., …Bliss, J. M. (2023). Data from Combined Perioperative Lapatinib and Trastuzumab in Early HER2-Positive Breast Cancer Identifies Early Responders: Randomized UK EPHOS-B Trial Long-Term Results. [Dataset]. https://doi.org/10.1158/1078-0432.c.6532623.v1

Purpose: EPHOS-B aimed to determine whether perioperative anti-HER2 therapy inhibited proliferation and/or increased apoptosis in HER2-positive breast cancer. Patients and Methods: This randomized phase II, two-part, multicenter trial included n... Read More about Data from Combined Perioperative Lapatinib and Trastuzumab in Early HER2-Positive Breast Cancer Identifies Early Responders: Randomized UK EPHOS-B Trial Long-Term Results.

Exploring cardiovascular risk and outcomes in primary care consulters for osteoarthritis using longitudinal electronic primary care data (2023)
Thesis
Huang, X. (2023). Exploring cardiovascular risk and outcomes in primary care consulters for osteoarthritis using longitudinal electronic primary care data. (Thesis). Keele University

For adults aged 45 and over in the United Kingdom (UK), osteoarthritis is a common reason for consultation with primary care. Cardiovascular disease (CVD) is a common comorbidity with osteoarthritis; two in five people with osteoarthritis also have C... Read More about Exploring cardiovascular risk and outcomes in primary care consulters for osteoarthritis using longitudinal electronic primary care data.

The association between gout and psychological co-morbidity: results from a prospective cohort study (2023)
Thesis
Higgs, J. J. R. (2023). The association between gout and psychological co-morbidity: results from a prospective cohort study. (Thesis). Keele University

Gout is associated with an increased risk of both physical-health co-morbidities and a reduction in physical health-related quality of life. However, the association between gout and psychological comorbidity (depression and anxiety) has received lit... Read More about The association between gout and psychological co-morbidity: results from a prospective cohort study.

Investigating the therapeutic potential of the glucocorticoid antagonist, mifepristone, for the treatment of spinal muscular atrophy (2023)
Thesis
Sutton, E. R. (2023). Investigating the therapeutic potential of the glucocorticoid antagonist, mifepristone, for the treatment of spinal muscular atrophy. (Thesis). Keele University

Spinal muscular atrophy (SMA) is a neuromuscular disease characterised by loss of alpha motor neurons and muscle atrophy. When untreated, mortality occurs within the first two years of life in the most severe cases. Extensive research has led to thre... Read More about Investigating the therapeutic potential of the glucocorticoid antagonist, mifepristone, for the treatment of spinal muscular atrophy.