Outputs (645)

Genome-wide Association of Rheumatoid Arthritis in the African Ancestry Identifies HLA Amino Acid Polymorphisms of Risk (2024)
Presentation / Conference Contribution
Zhang, H., Sakaue, . S., Posner, D., Cui, . J., Yang, D., Budu-Aggrey, A., Ho, Y.-L., Costa, L., Matty, R., Huang, S., Monach, P., Ishaigaki, K., Maripuri, M., Melley, C., Tanukonda, V., Sangar, R., McDermott, G., Jeffway, M., Laufer, V., Okada, Y., … Liao, K. Genome-wide Association of Rheumatoid Arthritis in the African Ancestry Identifies HLA Amino Acid Polymorphisms of Risk. Presented at ACR Convergence 2024, Washington DC

Background/Purpose: The association between RA and the MHC is largely explained by five amino acid (AA) positions: DRB1 positions 11, 13, 71, and 74, HLA-B position 9, and DPB1 position 9. However, these prior studies are from populations genetically... Read More about Genome-wide Association of Rheumatoid Arthritis in the African Ancestry Identifies HLA Amino Acid Polymorphisms of Risk.

A multidisciplinary weight management intervention for adults with severe mental illness in forensic psychiatric inpatient services (Motiv8): a single blind cluster-randomised wait-list controlled feasibility trial (2024)
Journal Article
Carney, R., Law, H., El-Metaal, H., Hann, M., Shields, G., Savage, S., Small, I., Jones, R., Shiers, D., Macafee, G., & Parker, S. (2024). A multidisciplinary weight management intervention for adults with severe mental illness in forensic psychiatric inpatient services (Motiv8): a single blind cluster-randomised wait-list controlled feasibility trial. Frontiers in Psychiatry, 15, 1-13. https://doi.org/10.3389/fpsyt.2024.1457864

Background: People with severe mental illness experience physical health inequalities and a 15–20-year premature mortality rate. Forensic inpatients are particularly affected by restrictions on movement, long admissions, and obesogenic/sedative psych... Read More about A multidisciplinary weight management intervention for adults with severe mental illness in forensic psychiatric inpatient services (Motiv8): a single blind cluster-randomised wait-list controlled feasibility trial.

Sex Differences in Patients Undergoing Left Main Stem Percutaneous Coronary Intervention for Stable Angina: Data From a National Registry. (2024)
Journal Article
Shamkhani, W., Zathar, Z., Khattak, S., Nolan, J., Chieffo, A., Kinnaird, T., & Mamas, M. A. (2024). Sex Differences in Patients Undergoing Left Main Stem Percutaneous Coronary Intervention for Stable Angina: Data From a National Registry. Journal of the American Heart Association, 13(22), Article e036569. https://doi.org/10.1161/JAHA.124.036569

Percutaneous coronary intervention (PCI) of the left main coronary artery (LMCA) for stable angina has steadily increased. Outcomes stratified by sex are inconclusive and limited. We assessed sex-based trends and differences in clinical outcomes amon... Read More about Sex Differences in Patients Undergoing Left Main Stem Percutaneous Coronary Intervention for Stable Angina: Data From a National Registry..

Should all people starting urate-lowering therapy for gout receive anti-inflammatory prophylaxis? (2024)
Journal Article
Roddy, E., Prior, J. A., & Mallen, C. D. (2024). Should all people starting urate-lowering therapy for gout receive anti-inflammatory prophylaxis?. Exploration of Musculoskeletal Diseases, 2, 521-528. https://doi.org/10.37349/emd.2024.00076

Co-prescription of anti-inflammatory prophylaxis with colchicine, non-steroidal anti-inflammatory drugs (NSAIDs), or corticosteroids when initiating urate-lowering therapy (ULT) for gout is recommended in clinical guidelines to prevent ULT-induced fl... Read More about Should all people starting urate-lowering therapy for gout receive anti-inflammatory prophylaxis?.

Contemporary epidemiology of hospitalised heart failure with reduced versus preserved ejection fraction in England: a retrospective, cohort study of whole-population electronic health records. (2024)
Journal Article
Fletcher, R. A., Rockenschaub, P., Neuen, B. L., Walter, I. J., Conrad, N., Mizani, M. A., Bolton, T., Lawson, C. A., Tomlinson, C., Logothetis, S. B., Petitjean, C., Brizzi, L. F., Kaptoge, S., Raffetti, E., Calvert, P. A., Di Angelantonio, E., Banerjee, A., Mamas, M. A., Squire, I., Denaxas, S., …Wood, A. M. (2024). Contemporary epidemiology of hospitalised heart failure with reduced versus preserved ejection fraction in England: a retrospective, cohort study of whole-population electronic health records. The Lancet, 9(11), e871-e885. https://doi.org/10.1016/S2468-2667%2824%2900215-9

Heart failure is common, complex, and often associated with coexisting chronic medical conditions and a high mortality. We aimed to assess the epidemiology of people admitted to hospital with heart failure with reduced ejection fraction (HFrEF) and h... Read More about Contemporary epidemiology of hospitalised heart failure with reduced versus preserved ejection fraction in England: a retrospective, cohort study of whole-population electronic health records..

Trends in Management and Consultations for Gout: A Study of 18 Million Adults Using the OpenSAFELY Platform (2024)
Presentation / Conference Contribution
Russell, M., Massey, J., Roddy, E., MacKenna, B., Bacon, S., Goldacre, B., Andrews, C., Hickman, G., Mehrkar, A., Mahto, A., Rutherford, A., Patel, S., Adas, M., Alveyn, E., Nagra, . D., Bechman, K., Ledingham, J., Hudson, J., Norton, S., Cope, A., & Galloway, J. (2024, November). Trends in Management and Consultations for Gout: A Study of 18 Million Adults Using the OpenSAFELY Platform. Poster presented at Abstract Supplement ACR Convergence 2024, Washington DC

Background/Purpose: Data from before the COVID-19 pandemic had shown persistently poor care for people with gout in many countries worldwide. Whether this was further exacerbated by the pandemic is not fully understood. Our objective was to investiga... Read More about Trends in Management and Consultations for Gout: A Study of 18 Million Adults Using the OpenSAFELY Platform.

Patient Anxiety, Fear, and Kinesiophobia: Challenges Shared by UK Physiotherapists in Managing Polymyalgia Rheumatica - Findings from a Qualitative Study (2024)
Presentation / Conference Contribution
O'Brien, A., Muller, S., Liddle, J., Thomas, M., & Mallen, C. D. (2024, November). Patient Anxiety, Fear, and Kinesiophobia: Challenges Shared by UK Physiotherapists in Managing Polymyalgia Rheumatica - Findings from a Qualitative Study. Poster presented at ACR Convergence 2024, Washington DC, USA

Risk of Hepatitis C Virus Infection in Tuberculosis Patients: A Systematic Review and Meta-Analysis (2024)
Journal Article
Amoori, N., Cheraghian, B., Amini, P., & Alavi, S. M. (2024). Risk of Hepatitis C Virus Infection in Tuberculosis Patients: A Systematic Review and Meta-Analysis. Iranian Journal of Public Health, 53(11), 2451-2461. https://doi.org/10.18502/ijph.v53i11.16947

Background: Tuberculosis (TB) and infection of Hepatitis C virus (HCV) have appeared as major public health problems. The present systematic review and meta-analysis aimed at determining the relationship between TB and the risk of HCV infection.

M... Read More about Risk of Hepatitis C Virus Infection in Tuberculosis Patients: A Systematic Review and Meta-Analysis.

Protocol for a mixed methods process evaluation for a randomised controlled trial to improve shared decision-making about, and uptake of, osteoporosis medicines: the iFraP study (2024)
Journal Article
Bullock, L., Cherrington, A., Clark, E. M., Fleming, J., Bentley, I., Nicholls, E., Webb, D., Smith, J., Bathers, S., Lewis, S., Horne, R., O'Neill, T. W., Mallen, C. D., Jinks, C., & Paskins, Z. (in press). Protocol for a mixed methods process evaluation for a randomised controlled trial to improve shared decision-making about, and uptake of, osteoporosis medicines: the iFraP study. NIHR Open Research, 4, 70. https://doi.org/10.3310/nihropenres.13751.1

Background
High quality shared decision-making (SDM) conversations involve people with or at risk of osteoporosis and clinicians working together to decide, where appropriate, which evidence-based medicines best fit the person’s life, beliefs, and v... Read More about Protocol for a mixed methods process evaluation for a randomised controlled trial to improve shared decision-making about, and uptake of, osteoporosis medicines: the iFraP study.

Abstract 4143813: Secular Trends and Mortality Rates in Percutaneous Coronary Intervention in Non-ST Elevation Acute Coronary Syndrome: 15-Year Nationwide Survey (2024)
Presentation / Conference Contribution
Abood, Z., Allaqaband, S., Sokhal, B., Tunink, K., Hommeida, M., Bajwa, T., & Jan, M. F. Abstract 4143813: Secular Trends and Mortality Rates in Percutaneous Coronary Intervention in Non-ST Elevation Acute Coronary Syndrome: 15-Year Nationwide Survey

Background: Non-ST elevation acute coronary syndrome (NSTE-ACS) is a leading cause of cardiovascular morbidity, with variable mortality across age groups. Older patients exhibit higher in-hospital mortality and often experience delayed percutaneous c... Read More about Abstract 4143813: Secular Trends and Mortality Rates in Percutaneous Coronary Intervention in Non-ST Elevation Acute Coronary Syndrome: 15-Year Nationwide Survey.