Outputs (2)

Characterisation of joint macrophages: implications for osteoarthritis (2017)
Journal Article
Garcia, J., Wei, W., Wright, K., Mennan, C., Roberts, S., Richardson, J., …Bastiaansen-Jenniskens, Y. (2017). Characterisation of joint macrophages: implications for osteoarthritis. International Journal of Experimental Pathology, 97(6),

Introduction Inflammation in the synovium is a feature of osteoarthritis (OA) that contributes to the general degradation of the joint by the secretion of pro-inflammatory molecules and degradative enzymes. The infrapatellar fat pad (IPFP) is an intr... Read More about Characterisation of joint macrophages: implications for osteoarthritis.

Human articular chondrocytes retain their phenotype in sustained hypoxia whilst normoxia promotes their immunomodulatory capacity (2017)
Presentation / Conference
Mennan, C., Owen, S., Garcia, J., McCarthy, H., Banerjee, R., Roberts, S., & Richardson, J. (2017, March). Human articular chondrocytes retain their phenotype in sustained hypoxia whilst normoxia promotes their immunomodulatory capacity. Poster presented at British Society for Matrix Biology “The Grey Area – Age and the Extracellular Matrix”

Introduction The maintenance of chondrogenic phenotype in human articular chondrocytes grown in continuous normoxic (21% O2) and hypoxic (2% O2) conditions was assessed, with the aim of finding the best environment for culturing cells destined for ca... Read More about Human articular chondrocytes retain their phenotype in sustained hypoxia whilst normoxia promotes their immunomodulatory capacity.