Outputs (2192)

Characterizing Biomechanics of Limbal Niche Using Vibrational Optical Coherence Elastography (2024)
Journal Article
Dimmock, R., Zhang, Y., Butt, G., Rauz, S., Huang, Z., & Yang, Y. (in press). Characterizing Biomechanics of Limbal Niche Using Vibrational Optical Coherence Elastography. Journal of Biophotonics, Article e202400172. https://doi.org/10.1002/jbio.202400172

The limbal niche is an adult source of epithelial stem cells which regenerate the cornea epithelium. The architecture and biomechanical properties of the limbus have previously been demonstrated to change due to aging and disease. This study aims to... Read More about Characterizing Biomechanics of Limbal Niche Using Vibrational Optical Coherence Elastography.

MSC–extracellular vesicle microRNAs target host cell-entry receptors in COVID-19: in silico modeling for in vivo validation (2024)
Journal Article
Al Saihati, H. A., Dessouky, A. A., Salim, R. F., Elgohary, I., El-Sherbiny, M., Ali, F. E. M., …Ebrahim, N. (in press). MSC–extracellular vesicle microRNAs target host cell-entry receptors in COVID-19: in silico modeling for in vivo validation. Stem Cell Research and Therapy, 15(1), 1-22. https://doi.org/10.1186/s13287-024-03889-9

Background: Coronavirus disease 2019 (COVID-19) has created a global pandemic with significant morbidity and mortality. SARS-CoV-2 primarily infects the lungs and is associated with various organ complications. Therapeutic approaches to combat COVID-... Read More about MSC–extracellular vesicle microRNAs target host cell-entry receptors in COVID-19: in silico modeling for in vivo validation.

V2 Ovine UC-MSCs Revised Manuscript (2024)
Journal Article
Perry, J., Mennan, C., Cool, P., McCarthy, H., Newell, K., Hopkins, T., …Roberts, S. (in press). V2 Ovine UC-MSCs Revised Manuscript. Cartilage,

Rate of revision and wear penetration in different polyethylene liner compositions in total hip arthroplasty: a Bayesian network meta-analysis (2024)
Journal Article
Migliorini, F., Betsch, M., Maffulli, N., Schäfer, L., Hildebrand, F., Kubach, J., & Pasurka, M. (in press). Rate of revision and wear penetration in different polyethylene liner compositions in total hip arthroplasty: a Bayesian network meta-analysis. Scientific Reports, 14(1), Article 21162. https://doi.org/10.1038/s41598-024-71326-1

The present Bayesian network meta-analysis compared different types of polyethylene liners in total hip arthroplasty (THA) in terms of wear penetration (mm/year) and rate of revision. The type of liners compared were the crosslinked ultra-high molecu... Read More about Rate of revision and wear penetration in different polyethylene liner compositions in total hip arthroplasty: a Bayesian network meta-analysis.

Update on the intriguing roles of AQP4 expression and redistribution in the progression and treatment of glioma (2024)
Journal Article
Lan, Y.-L., Zou, S., & Chen, R. (2024). Update on the intriguing roles of AQP4 expression and redistribution in the progression and treatment of glioma. Annals of Medicine, 56(1), https://doi.org/10.1080/07853890.2024.2401111

Aquaporin 4 (AQP4) isabundant in the human brain and has an important role in brain homeostatsis and diseases. AQP4 expression has been found to be associated with glioma malignancies. However, the complete understanding of the biological processes... Read More about Update on the intriguing roles of AQP4 expression and redistribution in the progression and treatment of glioma.

State of the Art in Sub-Phenotyping Midbrain Dopamine Neurons (2024)
Journal Article
Basso, V., Döbrössy, M. D., Thompson, L. H., Kirik, D., Fuller, H. R., & Gates, M. A. (2024). State of the Art in Sub-Phenotyping Midbrain Dopamine Neurons. Biology, 13(9), 690. https://doi.org/10.3390/biology13090690

Dopaminergic neurons in the ventral tegmental area (VTA) and the substantia nigra pars compacta (SNpc) comprise around 75% of all dopaminergic neurons in the human brain. While both groups of dopaminergic neurons are in close proximity in the midbrai... Read More about State of the Art in Sub-Phenotyping Midbrain Dopamine Neurons.

Return to Sport Following Arthroscopic Management of Femoroacetabular Impingement: A Systematic Review (2024)
Journal Article
Lucenti, L., Maffulli, N., Bardazzi, T., Saggini, R., Memminger, M., Simeone, F., & Migliorini, F. (in press). Return to Sport Following Arthroscopic Management of Femoroacetabular Impingement: A Systematic Review. Journal of Clinical Medicine, 13(17), https://doi.org/10.3390/jcm13175219

Background: Femoroacetabular impingement (FAI) is common. The present systematic review updates the current evidence on return to sport (RTS) in patients who have undergone arthroscopic surgery for FAI in any of its variants (CAM, pincer, or both). M... Read More about Return to Sport Following Arthroscopic Management of Femoroacetabular Impingement: A Systematic Review.

Osteoinductive potential of graphene and graphene oxide for bone tissue engineering: a comparative study (2024)
Journal Article
Kashte, S. B., Kadam, S., Maffulli, N., Potty, A. G., Migliorini, F., & Gupta, A. (2024). Osteoinductive potential of graphene and graphene oxide for bone tissue engineering: a comparative study. Journal of Orthopaedic Surgery and Research, 19(1), 1-11. https://doi.org/10.1186/s13018-024-05028-9

Background: Bone defects, especially critical-size bone defects, and their repair pose a treatment challenge. Osteoinductive scaffolds have gained importance given their potential in bone tissue engineering applications. Methods: Polycaprolactone (PC... Read More about Osteoinductive potential of graphene and graphene oxide for bone tissue engineering: a comparative study.

Lower cell number, lateral defect location and milder grade are associated with improved autologous chondrocyte implantation outcome (2024)
Journal Article
Tierney, L., Kuiper, J. H., Roberts, S., Snow, M., Williams, M., Harrington, M. B., …Wright, K. T. (in press). Lower cell number, lateral defect location and milder grade are associated with improved autologous chondrocyte implantation outcome. Knee Surgery, Sports Traumatology, Arthroscopy, https://doi.org/10.1002/ksa.12433

Purpose: To investigate patient demographic, injury and surgery/treatment‐associated factors that can influence the patient‐reported outcome (Lysholm score), following autologous chondrocyte implantation (ACI) in a large, ‘real‐world’, nonuniform, pr... Read More about Lower cell number, lateral defect location and milder grade are associated with improved autologous chondrocyte implantation outcome.

Nanoscale synchrotron x-ray analysis of intranuclear iron in melanised neurons of Parkinson’s substantia nigra (2024)
Journal Article
Brooks, J., Everett, J., Hill, E., Billimoria, K., Morris, C. M., Sadler, P. J., …Collingwood, J. F. (in press). Nanoscale synchrotron x-ray analysis of intranuclear iron in melanised neurons of Parkinson’s substantia nigra. Communications Biology, 7(1), Article 1024. https://doi.org/10.1038/s42003-024-06636-1

Neuromelanin-pigmented neurons of the substantia nigra are selectively lost during the progression of Parkinson’s disease. These neurons accumulate iron in the disease state, and iron-mediated neuron damage is implicated in cell death. Animal models... Read More about Nanoscale synchrotron x-ray analysis of intranuclear iron in melanised neurons of Parkinson’s substantia nigra.