Outputs (3)

Evaluating Joint Morbidity after Chondral Harvest for Autologous Chondrocyte Implantation (ACI): A Study of ACI-Treated Ankles and Hips with a Knee Chondral Harvest (2015)
Journal Article
McCarthy, H. S., Richardson, J. B., Parker, J. C., & Roberts, S. (2015). Evaluating Joint Morbidity after Chondral Harvest for Autologous Chondrocyte Implantation (ACI): A Study of ACI-Treated Ankles and Hips with a Knee Chondral Harvest. Cartilage, 7(1), 7-15. https://doi.org/10.1177/1947603515607963

Objective
To establish if harvesting cartilage to source chondrocytes for autologous chondrocyte implantation (ACI) results in donor site morbidity.

Design
Twenty-three patients underwent ACI for chondral defects of either the ankle or the hip.... Read More about Evaluating Joint Morbidity after Chondral Harvest for Autologous Chondrocyte Implantation (ACI): A Study of ACI-Treated Ankles and Hips with a Knee Chondral Harvest.

The expression of toll-like receptors on mesenchymal stem cells isolated from human umbilical cord (2015)
Journal Article
McCarthy, H., Mennan, C., Jesson, H., Ziya, S., & Roberts, S. (2015). The expression of toll-like receptors on mesenchymal stem cells isolated from human umbilical cord. International Journal of Experimental Pathology, 96(2), A27-A28

Wnt-signalling in human articular chondrocytes (2015)
Journal Article
McCarthy, H., Owen, S., & Roberts, S. (2015). Wnt-signalling in human articular chondrocytes. International Journal of Experimental Pathology, 96(2), A27

Introduction Aberrant Wnt-signalling in cartilage results inchondrocyte dedifferentiation, hypertrophy, loss of type II collagen, aggrecan and glycosaminoglycans. Articular chondrocytes experience a pO2 gradient from~6% (surface) to~1% (within deeper... Read More about Wnt-signalling in human articular chondrocytes.