Outputs (3)

Cell Therapy for Cartilage Repair (2021)
Journal Article
McCarthy, H., Perry, J., Hulme, C., Mennan, C., & Wright, K. (2021). Cell Therapy for Cartilage Repair. Emerging Topics in Life Sciences, 5(4), 575-589. https://doi.org/10.1042/ETLS20210015

Regenerative medicine, using cells as therapeutic agents for the repair or regeneration of tissues and organs, offers great hope for the future of medicine. Cell therapy for treating defects in articular cartilage has been an exemplar of translating... Read More about Cell Therapy for Cartilage Repair.

Human Mesenchymal Stromal Cells Enhance Cartilage Healing in a Murine Joint Surface Injury Model (2021)
Journal Article
Perry, J., Roelofs, A. J., Mennan, C., McCarthy, H. S., Richmond, A., Clark, S. M., Riemen, A. H., Wright, K., De Bari, C., & Roberts, S. (2021). Human Mesenchymal Stromal Cells Enhance Cartilage Healing in a Murine Joint Surface Injury Model. Cells, 1-16. https://doi.org/10.3390/cells10081999

Human umbilical cord (hUC)- or bone marrow (hBM)-derived mesenchymal stromal cells (MSCs) were evaluated as an allogeneic source of cells for cartilage repair. We aimed to determine if they could enhance healing of chondral defects with or without th... Read More about Human Mesenchymal Stromal Cells Enhance Cartilage Healing in a Murine Joint Surface Injury Model.

Identification of Candidate Synovial Fluid Biomarkers for the Prediction of Patient Outcome After Microfracture or Osteotomy (2021)
Journal Article
Hulme, C. H., Peffers, M. J., Harrington, G. M. B., Wilson, E., Perry, J., Roberts, S., Gallacher, P., Jermin, P., & Wright, K. T. (2021). Identification of Candidate Synovial Fluid Biomarkers for the Prediction of Patient Outcome After Microfracture or Osteotomy. American Journal of Sports Medicine, 49(6), 1512-1523. https://doi.org/10.1177/0363546521995565

Background:
Biomarkers are needed to predict clinical outcomes for microfracture and osteotomy surgeries to ensure patients can be better stratified to receive the most appropriate treatment.
Purpose:
To identify novel biomarker candidates and to... Read More about Identification of Candidate Synovial Fluid Biomarkers for the Prediction of Patient Outcome After Microfracture or Osteotomy.