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Outputs (47)

Tuning the properties of all natural polymeric scaffolds for tendon repair with cellulose microfibers (2024)
Journal Article
Diaz, F., Zimmermann, L., Dale, T. P., Forsyth, N. R., & Boccaccini, A. R. (2024). Tuning the properties of all natural polymeric scaffolds for tendon repair with cellulose microfibers. Carbohydrate Polymer Technologies and Applications, 7, Article 100447. https://doi.org/10.1016/j.carpta.2024.100447

Rotator cuff injuries affect a large percentage of the population worldwide. Surgical repair has rates of failure of up to 70%, and existing materials used in the reinforcement of injuries often lack appropriate mechanical properties and biodegradabi... Read More about Tuning the properties of all natural polymeric scaffolds for tendon repair with cellulose microfibers.

TERT Promoter Methylation Is Oxygen-Sensitive and Regulates Telomerase Activity (2024)
Journal Article
Dogan, F., & Forsyth, N. R. (in press). TERT Promoter Methylation Is Oxygen-Sensitive and Regulates Telomerase Activity. Biomolecules, 14(1), Article 131. https://doi.org/10.3390/biom14010131

Telomere repeats protect linear chromosomes from degradation, and telomerase has a prominent role in their maintenance. Telomerase has telomere-independent effects on cell proliferation, DNA replication, differentiation, and tumorigenesis. TERT (telo... Read More about TERT Promoter Methylation Is Oxygen-Sensitive and Regulates Telomerase Activity.

A ROLE FOR PERFUSION-DELIVERED SHEAR FORCE IN THE PROMOTION OF TPSC EV PRODUCTION (2024)
Conference Proceeding
Clerici, M., Ciardulli, M., Forsyth, N., Maffulli, N., & Della Porta, G. (2024). A ROLE FOR PERFUSION-DELIVERED SHEAR FORCE IN THE PROMOTION OF TPSC EV PRODUCTION. . https://doi.org/10.1302/1358-992x.2024.2.013

Tendon injuries are a common problem that can significantly impact an individual's quality of life. While traditional surgical methods have been used to address this issue, Extracellular Vesicles (EVs) have emerged as a promising approach to promote... Read More about A ROLE FOR PERFUSION-DELIVERED SHEAR FORCE IN THE PROMOTION OF TPSC EV PRODUCTION.

Injectable hydrogels: An emerging therapeutic strategy for cartilage regeneration. (2023)
Journal Article
Atwal, A., Dale, T. P., Snow, M., Forsyth, N. R., & Davoodi, P. (2023). Injectable hydrogels: An emerging therapeutic strategy for cartilage regeneration. Advances in colloid and interface science, 321, Article 103030. https://doi.org/10.1016/j.cis.2023.103030

The impairment of articular cartilage due to traumatic incidents or osteoarthritis has posed significant challenges for healthcare practitioners, researchers, and individuals suffering from these conditions. Due to the absence of an approved treatmen... Read More about Injectable hydrogels: An emerging therapeutic strategy for cartilage regeneration..

Endotenon-Derived Type II Tendon Stem Cells Have Enhanced Proliferative and Tenogenic Potential (2023)
Journal Article
Clerici, M., Citro, V., Byrne, A. L., P. Dale, T., Boccaccini, A. R., Della Porta, G., …Forsyth, N. R. (2023). Endotenon-Derived Type II Tendon Stem Cells Have Enhanced Proliferative and Tenogenic Potential. International Journal of Molecular Sciences, 24(20), Article 15107. https://doi.org/10.3390/ijms242015107

Tendon injuries caused by overuse or age-related deterioration are frequent. Incomplete knowledge of somatic tendon cell biology and their progenitors has hindered interventions for the effective repair of injured tendons. Here, we sought to compare... Read More about Endotenon-Derived Type II Tendon Stem Cells Have Enhanced Proliferative and Tenogenic Potential.

Tendon tissue engineering: An overview of biologics to promote tendon healing and repair (2023)
Journal Article
Citro, V., Clerici, M., Boccaccini, A. R., Della Porta, G., Maffulli, N., & Forsyth, N. R. (2023). Tendon tissue engineering: An overview of biologics to promote tendon healing and repair. Journal of Tissue Engineering,

Tendons are dense connective tissues with a hierarchical polarized structure that respond to and adapt to the transmission of muscle contraction forces to the skeleton, enabling motion and maintaining posture. Tendon injuries, also known as tendinopa... Read More about Tendon tissue engineering: An overview of biologics to promote tendon healing and repair.