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Outputs (6)

P31 Role of sesquiterpene lactones against human ovarian cancer (2017)
Journal Article
Fadayomi, I. E., Forsyth, N., & Li, W. (2017). P31 Role of sesquiterpene lactones against human ovarian cancer. Biochemical Pharmacology, 139(11), 134-135. https://doi.org/10.1016/j.bcp.2017.06.032

Background: Overexpression of microRNA-31 (miR-31) is implicated in the pathogenesis of esophageal squamous cell carcinoma (ESCC), a deadly disease associated with dietary zinc deficiency. Using a rat model that recapitulates features of human ESCC,... Read More about P31 Role of sesquiterpene lactones against human ovarian cancer.

Identification and evaluation of anticancer compounds from three Nigerian plants used in traditional medicines (2017)
Presentation / Conference
Rosa Johnson-Ajinwo, O., Richardson, A., & Li, W. (2017, September). Identification and evaluation of anticancer compounds from three Nigerian plants used in traditional medicines. Presented at IUPHAR, Aberdeen

Ovarian cancer is the second leading cause of death among women in the gynaecological category of cancers. The current post surgery treatment which involves the use of platinum-based therapy with its attendant adverse drug-resistance often results in... Read More about Identification and evaluation of anticancer compounds from three Nigerian plants used in traditional medicines.

Advanced glycation products' levels and mechanical properties of vaginal tissue in pregnancy (2017)
Journal Article
Weli, H. K., Akhtar, R., Chang, Z., Li, W., Cooper, J., & Yang, Y. (2017). Advanced glycation products' levels and mechanical properties of vaginal tissue in pregnancy. European Journal of Obstetrics and Gynecology and Reproductive Biology, 78-85. https://doi.org/10.1016/j.ejogrb.2017.04.037

Objectives Non-enzymatic glycation is closely associated with altered mechanical properties of connective tissue. Pregnancy, marked with high levels of female hormones, confers unique alteration to the mechanical properties of pelvic connective tiss... Read More about Advanced glycation products' levels and mechanical properties of vaginal tissue in pregnancy.

Antibacterial and antibiotic potentiating activities of tropical marine sponge extracts (2017)
Journal Article
Beesoo, R., Bhagooli, R., Neergheen-Bhujun, V. S., Li, W., Kagansky, A., & Bahorun, T. (2017). Antibacterial and antibiotic potentiating activities of tropical marine sponge extracts. Comparative Biochemistry and Physiology - Part C: Toxicology and Pharmacology, 81-90. https://doi.org/10.1016/j.cbpc.2017.04.001

Increasing prevalence of antibiotic resistance has led research to focus on discovering new antimicrobial agents derived from the marine biome. Although ample studies have investigated sponges for their bioactive metabolites with promising prospects... Read More about Antibacterial and antibiotic potentiating activities of tropical marine sponge extracts.

A characterization of the antimalarial activity of the bark of Cylicodiscus gabunensis Harms (2017)
Journal Article
Aldulaimi, O., Uche a, F. I., Hameed, H., Mbye, H., Ullah, I., Drijfhout, F., …Li, W. (2017). A characterization of the antimalarial activity of the bark of Cylicodiscus gabunensis Harms. Journal of Ethnopharmacology, 198, 221-225. https://doi.org/10.1016/j.jep.2017.01.014

Ethnopharmacological relevance and aim A decoction of the bark of Cylicodiscus gabunensis Harms is used as a traditional medicine in the treatment of malaria in Nigeria. This study aims to validate the antimalarial potency of this decoction in vitro... Read More about A characterization of the antimalarial activity of the bark of Cylicodiscus gabunensis Harms.