Outputs (14)

Assessment of fracture risk tools in care home residents (2019)
Thesis
Ihama, F. E. (2019). Assessment of fracture risk tools in care home residents. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/415215

Introduction Fragility fractures are common in care home residents. National guidelines recommend risk assessment to allow initiation of prophylactic measures. Currently available risk assessment tools have been tested in community dwelling adults b... Read More about Assessment of fracture risk tools in care home residents.

Developing an alveolar model to test the regenerative potential of placental membrane mesenchymal stem cells in bronchopulmonary dysplasia (2019)
Thesis
Bratt, J. A. (2019). Developing an alveolar model to test the regenerative potential of placental membrane mesenchymal stem cells in bronchopulmonary dysplasia. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/415216

Bronchopulmonary dysplasia (BPD) is a neonatal disease affecting the lungs of premature infants. Prematurely born infants have under-developed lungs and require invasive ventilation technologies to provide sufficient oxygen for survival. Artificial v... Read More about Developing an alveolar model to test the regenerative potential of placental membrane mesenchymal stem cells in bronchopulmonary dysplasia.

Development of conjunctival and retinal models for improved eye disease treatments (2019)
Thesis
Gater, R. V. A. (2019). Development of conjunctival and retinal models for improved eye disease treatments. (Thesis). Keele University

Eye diseases such as glaucoma, macular degeneration and retinitis pigmentosa can lead to significant sight problems and blindness if left untreated. Current treatments are invasive, have a low success rate and lack the ability to regenerate damaged o... Read More about Development of conjunctival and retinal models for improved eye disease treatments.

Antimicrobial nano-ninjas as chaperones of gemcitabine for pancreatic cancer (2019)
Thesis
Foulkes, R. L. (2019). Antimicrobial nano-ninjas as chaperones of gemcitabine for pancreatic cancer. (Thesis). Keele University

Pancreatic cancer is well known for its extremely high death rate, with the current treatments purely used to extend and better the quality of the patient's life instead of providing a “cure”. Because of this, novel drug delivery methods are being lo... Read More about Antimicrobial nano-ninjas as chaperones of gemcitabine for pancreatic cancer.

Investigating the possible mechanisms and gender effects of Omega-3 fatty acids on neuroblastoma, breast and prostate cancers (2019)
Thesis
Sutton, E. R. (2019). Investigating the possible mechanisms and gender effects of Omega-3 fatty acids on neuroblastoma, breast and prostate cancers. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/417795

Cancer is a worldwide disease characterised by uncontrollable cell division and tumour growth making it a leading cause of death worldwide. The use of dietary products such a poly-unsaturated fatty acids (PUFAs) to reduce cancer growth is a current a... Read More about Investigating the possible mechanisms and gender effects of Omega-3 fatty acids on neuroblastoma, breast and prostate cancers.

The use of virtual patients for developing the evidence informed, shared decision making of clinicians (2019)
Thesis
Jacklin, S. (2019). The use of virtual patients for developing the evidence informed, shared decision making of clinicians. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/414956

Background Shared decision-making (SDM) involves a patient and a health professional sharing information to arrive at a decision that aligns with both the best available evidence and the patient’s preferences. Research shows that SDM is not occurrin... Read More about The use of virtual patients for developing the evidence informed, shared decision making of clinicians.

A urinary proteomics investigation of pregnancy-related complications (2019)
Thesis
Al-Jasim, W. F. (2019). A urinary proteomics investigation of pregnancy-related complications. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/414917

Pre-eclampsia (PE) and intrauterine growth restriction (IUGR) are common disorders associated with placental implantation abnormalities in early pregnancy. Both conditions are heterogeneous, having complex and multiple aetiologies. PE complicates 5-8... Read More about A urinary proteomics investigation of pregnancy-related complications.

Exploring the erythrocyte invasion–blocking effect of modified heparin and heparin mimetics in the human malaria parasite Plasmodium falciparum (2019)
Thesis
Hmoud, M. K. (2019). Exploring the erythrocyte invasion–blocking effect of modified heparin and heparin mimetics in the human malaria parasite Plasmodium falciparum. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/414945

Despite the efforts in malaria eradication and elimination, malaria still poses a global challenge to health that, through the spread of antimalarial resistance, highlights an urgent need for new approaches for malaria treatment. Heparin and sulphate... Read More about Exploring the erythrocyte invasion–blocking effect of modified heparin and heparin mimetics in the human malaria parasite Plasmodium falciparum.

Applied statistical methods for prediction modelling of upper limb functional recovery after stroke (2019)
Thesis
Al-Shallawi, A. N. S. (2019). Applied statistical methods for prediction modelling of upper limb functional recovery after stroke. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/414444

Stroke is the third largest cause of death in the world, with a significant contribution to disability. Motor function impairment, encompassing upper limb impairment, is the most significant post-stroke impairment. Such an impairment contributes to r... Read More about Applied statistical methods for prediction modelling of upper limb functional recovery after stroke.

Exploring the effects of gestational diabetes on placental membrane derived stem cells (2019)
Thesis
Chen, L. (2019). Exploring the effects of gestational diabetes on placental membrane derived stem cells. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/414443

The progression of regenerative medicine and advanced cell banking technology provide the hope of using perinatal tissue-derived autologous MSCs for personalised medicine. Mesenchymal stem cells (MSCs) derived from placenta, with the advantages of be... Read More about Exploring the effects of gestational diabetes on placental membrane derived stem cells.