Outputs (177)

Interface modification in Co/Cu multilayers prepared by ion-assisted deposition (1998)
Thesis
Telling, N. Interface modification in Co/Cu multilayers prepared by ion-assisted deposition. (Thesis). Loughborough University. Retrieved from https://keele-repository.worktribe.com/output/828742

The interfacial structure of Co/Cu multilayers deposited under energetic ion bombardment has been investigated using X-ray reflectivity techniques. An ionassisted deposition system, based on unbalanced magnetron sputtering principles, has been develo... Read More about Interface modification in Co/Cu multilayers prepared by ion-assisted deposition.

Apoptosis and its association with immunomodulation and disease in common carp (Cyprinus carpio L.)
Thesis
(2013). Apoptosis and its association with immunomodulation and disease in common carp (Cyprinus carpio L.)

Stimulating the Immune system of fish by oral administration of immunomodulatory substances can prevent disease outbreaks in aquaculture. Yeast p( l ,3/1 ,6)-glucan, the active ingredient of the commercially available feed supplement MacroGard®, has... Read More about Apoptosis and its association with immunomodulation and disease in common carp (Cyprinus carpio L.).

Development of new heterocyclic leads against malaria
Thesis
(2013). Development of new heterocyclic leads against malaria

Malaria continues to pose a significant global health and socio-economic burden on those regions where it is endemic. Despite substantial investment in the delivery of artemisinin-based combination therapies, causing a fall in malaria mortality, re... Read More about Development of new heterocyclic leads against malaria.

Investigating the effects of oxygen tension and electrospun nanofibre topography on the adhesion of embryonic stem cells
Thesis
(2013). Investigating the effects of oxygen tension and electrospun nanofibre topography on the adhesion of embryonic stem cells

Human embryonic stem cells (hESCs) have the potential to differentiate into all cell types of the three germ layers. However, various limitations hinder their use in the clinic, including possibilities of teratoma formation, xenogenic exposure throug... Read More about Investigating the effects of oxygen tension and electrospun nanofibre topography on the adhesion of embryonic stem cells.

Optimisation and characterisation of human corneal stromal models
Thesis
(2013). Optimisation and characterisation of human corneal stromal models

The native corneal structure is highly organised and unified in architecture with structural and functional integration which mediates its transparency and mechanical strength. Two of the most demanding challenges in corneal tissue engineering are th... Read More about Optimisation and characterisation of human corneal stromal models.

Epidrug-mediated reversal of epigenetic changes associated with pituitary adenomas
Thesis
(2013). Epidrug-mediated reversal of epigenetic changes associated with pituitary adenomas

The genesis and outgrowth of pituitary adenomas is consequent to the combined contributions of genetic and epigenetic aberrations. Although the relative contribution of each is not known it is likely that particular aberration may be common or partic... Read More about Epidrug-mediated reversal of epigenetic changes associated with pituitary adenomas.

An investigation into the role of dendrimers as potential enhancers of the dermal delivery of topically applied chlorhexidine
Thesis
(2013). An investigation into the role of dendrimers as potential enhancers of the dermal delivery of topically applied chlorhexidine

The reduction of bacteria on the skin results in prophylactic and therapeutic benefits by reducing the occurrence of skin infections. Currently, chlorhexidine digluconate, a conventional topical antiseptic, permeates the skin poorly leaving viable op... Read More about An investigation into the role of dendrimers as potential enhancers of the dermal delivery of topically applied chlorhexidine.

Investigations into the effects of cholesterol inhibitors on cancer cells in vitro
Thesis
(2014). Investigations into the effects of cholesterol inhibitors on cancer cells in vitro

Cholesterol-rich membrane microdomains have a significant role in cancer progression, particularly in metastasis, and there is evidence that cholesterol inhibitors, most notably statins, can change the behaviour of cancer cells in vitro and in vivo.... Read More about Investigations into the effects of cholesterol inhibitors on cancer cells in vitro.

Investigation of the pituitary epigenome: a genome-wide analysis of changes associated with sporadic tumours
Thesis
(2014). Investigation of the pituitary epigenome: a genome-wide analysis of changes associated with sporadic tumours

Pituitary tumours harbour epigenetic aberrations; however, characterisation of these aberrations, on a genome-wide basis, is hampered by their infrequent occurrence and their small size. To overcome the constraint of limited tissue, whole genome ampl... Read More about Investigation of the pituitary epigenome: a genome-wide analysis of changes associated with sporadic tumours.

Hydrogen cyanide as an in-vitro and in-vivo marker of Pseudomonas aeruginosa infection
Thesis
(2014). Hydrogen cyanide as an in-vitro and in-vivo marker of Pseudomonas aeruginosa infection

The work presented in this thesis uses Selected Ion Flow Tube Mass Spectrometry to investigate if hydrogen cyanide (HCN) is a marker of Pseudomonas aeruginosa (PA). The initial in-vitro studies measure the HCN released into the gas phase by cultures... Read More about Hydrogen cyanide as an in-vitro and in-vivo marker of Pseudomonas aeruginosa infection.