Outputs (114)

A facile in vitro model to study rapid mineralization in bone tissues (2014)
Journal Article
Yang, Y. (2014). A facile in vitro model to study rapid mineralization in bone tissues. BioMedical Engineering OnLine, 136 - ?. https://doi.org/10.1186/1475-925X-13-136

BACKGROUND: Mineralization in bone tissue involves stepwise cell-cell and cell-ECM interaction. Regulation of osteoblast culture microenvironments can tailor osteoblast proliferation and mineralization rate, and the quality and/or quantity of the fin... Read More about A facile in vitro model to study rapid mineralization in bone tissues.

Fit for purpose? A qualitative study of key stakeholders’ perspectives on pharmaceutical needs assessments. (2014)
Presentation / Conference
Hamilton, J., Cork, T., Zaman, H., & White, S. (2014, September). Fit for purpose? A qualitative study of key stakeholders’ perspectives on pharmaceutical needs assessments. Poster presented at Royal Pharmaceutical Society (RPS), Annual Conference 2014, ICC Birmingham UK

PNAs were introduced in 2004, revised by Primary Care Trusts (PCTs) between 2009 and 2011 and, since April 2013, are in the process of being reviewed again by the new Health and Wellbeing Boards (HWBs) for completion in 2015. A previous questionnaire... Read More about Fit for purpose? A qualitative study of key stakeholders’ perspectives on pharmaceutical needs assessments..

Daylight robbery: Hospitals admissions for childhood asthma in English regions are inversely associated with hours of sunshine (2014)
Presentation / Conference
Carroll, W., Saunders, A., Ismail, K., Farrell, W., Emes, R., & Fryer, A. (2014, September). Daylight robbery: Hospitals admissions for childhood asthma in English regions are inversely associated with hours of sunshine. Presented at 22nd Annual Congress, Munich, Germany

Background: Vitamin D is implicated in the expression of childhood asthma but it is difficult to pick apart cause and effect from observational data. If lack of vitamin D is secondary to a sedentary lifestyle then weather patterns should not effect a... Read More about Daylight robbery: Hospitals admissions for childhood asthma in English regions are inversely associated with hours of sunshine.

Probing single-tumor cell interactions with different-age type I collagen networks by synchrotron-based Fourier transform infrared microspectroscopy (2014)
Journal Article
Guilbert, M., Eklouh-Molinier, C., Wehbe, K., Sulé-Suso, J., Yang, Y., Cinque, G., …Sockalingum, G. D. (2014). Probing single-tumor cell interactions with different-age type I collagen networks by synchrotron-based Fourier transform infrared microspectroscopy. Journal of Biomedical Optics, 19(11), 111612. https://doi.org/10.1117/1.jbo.19.11.111612

We report here on a first study using synchrotron radiation-based Fourier transform infrared microspectroscopy and imaging to investigate HT1080 human fibrosarcoma cells grown onto different-aged type I collagen networks. Spectral images were analy... Read More about Probing single-tumor cell interactions with different-age type I collagen networks by synchrotron-based Fourier transform infrared microspectroscopy.

Synthesis and cytotoxicity of thieno[2,3-b]pyridine and furo[2,3-b]pyridine derivatives (2014)
Journal Article
Hung, J. M., Arabshahi, H. J., Leung, E., Reynisson, J., & Barker, D. (2014). Synthesis and cytotoxicity of thieno[2,3-b]pyridine and furo[2,3-b]pyridine derivatives. European Journal of Medicinal Chemistry, 86, 420-437. https://doi.org/10.1016/j.ejmech.2014.09.001

Forty seven thieno[2,3-b]pyridines-2-carboxamides, furo[2,3-b]pyridines-2-carboxamides and tetrahydrothieno[2,3-b]quinolones-2-carboxamides derivatives were synthesized and tested for their antiproliferative activity against the NCI-60 cell lines. Th... Read More about Synthesis and cytotoxicity of thieno[2,3-b]pyridine and furo[2,3-b]pyridine derivatives.

Diagnosis and management of Neuro-Behçet's disease: international consensus recommendations. (2014)
Journal Article
(2014). Diagnosis and management of Neuro-Behçet's disease: international consensus recommendations. Journal of Neurology, 1662 - 1676. https://doi.org/10.1007/s00415-013-7209-3

Neuro-Behçet's disease (NBD) is one of the more serious manifestations of Behçet's disease (BD), which is a relapsing inflammatory multisystem disease with an interesting epidemiology. Though NBD is relatively uncommon, being potentially treatable, n... Read More about Diagnosis and management of Neuro-Behçet's disease: international consensus recommendations..

Optimizing nanomedicine pharmacokinetics using physiologically based pharmacokinetics modelling (2014)
Journal Article
(2014). Optimizing nanomedicine pharmacokinetics using physiologically based pharmacokinetics modelling. British Journal of Pharmacology, 3963-3979. https://doi.org/10.1111/bph.12604

The delivery of therapeutic agents is characterized by numerous challenges including poor absorption, low penetration in target tissues and non-specific dissemination in organs, leading to toxicity or poor drug exposure. Several nanomedicine strategi... Read More about Optimizing nanomedicine pharmacokinetics using physiologically based pharmacokinetics modelling.

The effect of a phospholipase C gamma inhibitor on the proliferation and phenotype of Du145 prostate cancer cells (2014)
Presentation / Conference
Muzinic, N. R., Mastelic, A., Markotic, A., Culic, V. C., Ross, A., Vuica-Ross, M., …Reynisson, J. (2014, August). The effect of a phospholipase C gamma inhibitor on the proliferation and phenotype of Du145 prostate cancer cells. Poster presented at FEBS EMBO 2014 Conference, Paris, France

Introduction: Prostate cancer remains the second most common cause of cancer related death among men, highlighting the need for new therapies. Many cancer cellular functions have been dis-covered to be regulated by phospholipase C (PLC) gamma activat... Read More about The effect of a phospholipase C gamma inhibitor on the proliferation and phenotype of Du145 prostate cancer cells.

Pharmacy students’ perceptions on interacting with people with mental health problems: a qualitative study (2014)
Conference Proceeding
Sidhu, J., Zamanb, H., & White, S. (2014). Pharmacy students’ perceptions on interacting with people with mental health problems: a qualitative study.

Previous research suggests that pharmacy workplace contact and the mental health content of undergraduate pharmacy education may not improve students’ negative attitudes towards people with mental health problems.1 However, studies have not explored... Read More about Pharmacy students’ perceptions on interacting with people with mental health problems: a qualitative study.

Signalling pathways involved in the synergistic effects of human growth differentiation factor 9 and bone morphogenetic protein 15 (2014)
Journal Article
Reader, K. L., Mottershead, D. G., Martin, G. A., Gilchrist, R. B., Heath, D. A., McNatty, K. P., & Juengel, J. L. (2016). Signalling pathways involved in the synergistic effects of human growth differentiation factor 9 and bone morphogenetic protein 15. Reproduction, Fertility and Development, 28(4), 491. https://doi.org/10.1071/rd14099

Growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) act synergistically to regulate granulosa cell proliferation and steroid production in several species. Several non-Sma and mothers against decapentaplegic (SMAD) signal... Read More about Signalling pathways involved in the synergistic effects of human growth differentiation factor 9 and bone morphogenetic protein 15.