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The Stroke Oxygen Study (SO2S) - a multi-center, study to assess whether routine oxygen treatment in the first 72 hours after a stroke improves long-term outcome: study protocol for a randomized controlled trial. (2014)
Journal Article
Roffe, C., Nevatte, T., Crome, P., Gray, R., Sim, J., Pountain, S., …Handy, P. (2014). The Stroke Oxygen Study (SO2S) - a multi-center, study to assess whether routine oxygen treatment in the first 72 hours after a stroke improves long-term outcome: study protocol for a randomized controlled trial. Trials, 15, Article 99. https://doi.org/10.1186/1745-6215-15-99

BACKGROUND: Mild hypoxia is common in stroke patients and may have significant adverse effects on the ischemic brain after stroke. The use of oxygen treatment is rapidly increasing in European stroke units but is not without side effects. It impedes... Read More about The Stroke Oxygen Study (SO2S) - a multi-center, study to assess whether routine oxygen treatment in the first 72 hours after a stroke improves long-term outcome: study protocol for a randomized controlled trial..

Are umbilical cord mesenchymal stem cells advantageous over bone marrow mesenchymal stem cells for cell therapy in orthopaedics? (2014)
Conference Proceeding
Mennan, C., Owen, S., Mayrogonatou, E., Kletsas, D., Oldershaw, R., Richardson, J., & Roberts, S. (2014). Are umbilical cord mesenchymal stem cells advantageous over bone marrow mesenchymal stem cells for cell therapy in orthopaedics?. . https://doi.org/10.1016/j.joca.2014.02.924

Purpose: Mesenchymal Stem cells (MSC) from umbilical cords (UC) are of increasing interest for cell therapy in degenerative musculoskeletal disorders as they present little ethical consideration and are reported to contain immune privileged cells, wh... Read More about Are umbilical cord mesenchymal stem cells advantageous over bone marrow mesenchymal stem cells for cell therapy in orthopaedics?.

Effect of anxiolytic and hypnotic drug prescriptions on mortality hazards: retrospective cohort study (2014)
Journal Article
Weich, S., Pearce, H. L., Croft, P., Singh, S., Crome, I., Bashford, J., & Frisher, M. (2014). Effect of anxiolytic and hypnotic drug prescriptions on mortality hazards: retrospective cohort study. BMJ, 348(mar19 5), g1996-g1996. https://doi.org/10.1136/bmj.g1996

Objective To test the hypothesis that people taking anxiolytic and hypnotic drugs are at increased risk of premature mortality, using primary care prescription records and after adjusting for a wide range of potential confounders. Design Retrospec... Read More about Effect of anxiolytic and hypnotic drug prescriptions on mortality hazards: retrospective cohort study.

Large, binge-type meals of high fat diet change feeding behaviour and entrain food anticipatory activity in mice (2014)
Journal Article
Bake, T., Murphy, M., Morgan, D., & Mercer, J. (2014). Large, binge-type meals of high fat diet change feeding behaviour and entrain food anticipatory activity in mice. Appetite, 77, 60 - 71. https://doi.org/10.1016/j.appet.2014.02.020

Male C57BL/6 mice fed ad libitum on control diet but allowed access to a palatable high fat diet (HFD) for 2?h a day during the mid-dark phase rapidly adapt their feeding behaviour and can consume nearly 80% of their daily caloric intake during this... Read More about Large, binge-type meals of high fat diet change feeding behaviour and entrain food anticipatory activity in mice.

Growth hormone secretagogue receptor deficiency in mice protects against obesity-induced hypertension (2014)
Journal Article
Harris, L. E., Morgan, D. G., & Balthasar, N. (2014). Growth hormone secretagogue receptor deficiency in mice protects against obesity-induced hypertension. Physiological Reports, 2(3), e00240-?. https://doi.org/10.1002/phy2.240

Growth hormone secretagogue receptor (GHS-R) signaling has been associated with growth hormone release, increases in food intake and pleiotropic cardiovascular effects. Recent data demonstrated that acute GHS-R antagonism leads to increases in mean a... Read More about Growth hormone secretagogue receptor deficiency in mice protects against obesity-induced hypertension.

Benefits and harms of extending the duration of dual antiplatelet therapy after percutaneous coronary intervention with drug-eluting stents: a meta-analysis (2014)
Journal Article
(2014). Benefits and harms of extending the duration of dual antiplatelet therapy after percutaneous coronary intervention with drug-eluting stents: a meta-analysis. Scientific World Journal, https://doi.org/10.1155/2014/794078

Background. The optimal duration of dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) is unclear. Methods. We conducted a systematic review and meta-analysis of randomized controlled trials evaluating risk of adverse eve... Read More about Benefits and harms of extending the duration of dual antiplatelet therapy after percutaneous coronary intervention with drug-eluting stents: a meta-analysis.

Label free cell tracking in 3-D tissue engineering constructs with high resolution imaging (2014)
Journal Article
Smith, W., Lam, K., Dempsey, K., Mazzocchi-Jones, D., Richardson, J., & Yang, Y. (2014). Label free cell tracking in 3-D tissue engineering constructs with high resolution imaging. Proceedings of SPIE, https://doi.org/10.1117/12.2039354

Within the field of tissue engineering there is an emphasis on studying 3-D live tissue structures. Consequently, to investigate and identify cellular activities and phenotypes in a 3-D environment for all in vitro experiments, including shape, migra... Read More about Label free cell tracking in 3-D tissue engineering constructs with high resolution imaging.

Reactions of tertiary propargyl alcohols with sodium halides under oxidative conditions (2014)
Journal Article
Aborways, M. M., & Moran, W. J. (2014). Reactions of tertiary propargyl alcohols with sodium halides under oxidative conditions. Tetrahedron Letters, 55(13), 2127-2129. https://doi.org/10.1016/j.tetlet.2014.02.042

The study of the reactions of tertiary propargyl alcohols with sodium halides under oxidative conditions is presented. With sodium iodide, α-iodoenones were formed, however, with sodium bromide or chloride the α-haloenones were only formed in low yie... Read More about Reactions of tertiary propargyl alcohols with sodium halides under oxidative conditions.

A comparison of psychotropic medication prescribing patterns in East of England prisons and the general population (2014)
Journal Article
Hassan, L., Senior, J., Frisher, M., Edge, D., & Shaw, J. (2014). A comparison of psychotropic medication prescribing patterns in East of England prisons and the general population. Journal of Psychopharmacology, 28(4), 357-362. https://doi.org/10.1177/0269881114523863

While the prevalence of mental illness is higher in prisons than in the community, less is known about comparative rates of psychotropic medicine prescribing. This is the first study in a decade to determine the prevalence and patterns of psychotropi... Read More about A comparison of psychotropic medication prescribing patterns in East of England prisons and the general population.