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Prolonged PR interval, first-degree heart block and adverse cardiovascular outcomes: a systematic review and meta-analysis (2016)
Journal Article
Mamas, Rashid, M., & Nolan, J. (2016). Prolonged PR interval, first-degree heart block and adverse cardiovascular outcomes: a systematic review and meta-analysis. Heart, https://doi.org/10.1136/heartjnl-2015-308956

Abstract Objective: First-degree atrioventricular block is frequently encountered in clinical practice and is generally considered a benign process. However, there is emerging evidence that prolonged PR interval may be associated with adverse outcome... Read More about Prolonged PR interval, first-degree heart block and adverse cardiovascular outcomes: a systematic review and meta-analysis.

Temporal Analyses of the Response of Intervertebral Disc Cells and Mesenchymal Stem Cells to Nutrient Deprivation (2016)
Journal Article
Wright, K., & Roberts, S. (2016). Temporal Analyses of the Response of Intervertebral Disc Cells and Mesenchymal Stem Cells to Nutrient Deprivation. Stem Cells International, 5415901 - ?

Much emphasis has been placed recently on the repair of degenerate discs using implanted cells, such as disc cells or bone marrow derived mesenchymal stem cells (MSCs). This study examines the temporal response of bovine and human nucleus pulposus (N... Read More about Temporal Analyses of the Response of Intervertebral Disc Cells and Mesenchymal Stem Cells to Nutrient Deprivation.

Endocytotic potential governs magnetic particle loading in dividing neural cells: studying modes of particle inheritance. (2016)
Journal Article
Tickle, J., Jenkins, S., Polyak, B., Pickard, M., & Chari, D. (2016). Endocytotic potential governs magnetic particle loading in dividing neural cells: studying modes of particle inheritance. Nanomedicine, 345 - 358. https://doi.org/10.2217/nnm.15.202

AIM: To achieve high and sustained magnetic particle loading in a proliferative and endocytotically active neural transplant population (astrocytes) through tailored magnetite content in polymeric iron oxide particles. MATERIALS & METHODS: MPs of var... Read More about Endocytotic potential governs magnetic particle loading in dividing neural cells: studying modes of particle inheritance..

A multinational cross-sectional survey of the management of patient medication adherence by European Healthcare Professionals (2016)
Journal Article
(2016). A multinational cross-sectional survey of the management of patient medication adherence by European Healthcare Professionals. BMJ Open, e009610. https://doi.org/10.1136/bmjopen-2015-009610

Objectives To examine which interventions healthcare professionals use to support patients with taking medicines and their perceptions about the effectiveness of those actions. Design Cross-sectional multinational study. Setting Online surve... Read More about A multinational cross-sectional survey of the management of patient medication adherence by European Healthcare Professionals.

Bile duct reconstruction following laparoscopic cholecystectomy in England (2016)
Journal Article
(2016). Bile duct reconstruction following laparoscopic cholecystectomy in England. Surgical Endoscopy, 3516- 3525. https://doi.org/10.1007/s00464-015-4641-8

Objectives To determine the incidence of bile duct reconstruction (BDR) following laparoscopic cholecystectomy (LC) and to identify associated risk factors. Background Major bile duct injury (BDI) requiring reconstruction is a serious complicati... Read More about Bile duct reconstruction following laparoscopic cholecystectomy in England.

Habitual chocolate consumption and the risk of incident heart failure among healthy men and women (2016)
Journal Article
Mamas. (2016). Habitual chocolate consumption and the risk of incident heart failure among healthy men and women. Nutrition, Metabolism and Cardiovascular Diseases, 722 -734. https://doi.org/10.1016/j.numecd.2016.01.003

BACKGROUND: We aimed to examine the association between chocolate intake and the risk of incident heart failure in a UK general population. We conducted a systematic review and meta-analysis to quantify this association. METHODS AND RESULTS: We used... Read More about Habitual chocolate consumption and the risk of incident heart failure among healthy men and women.

Habitual chocolate consumption and the risk of incident heart failure among healthy men and women (2016)
Journal Article
Mamas. (2016). Habitual chocolate consumption and the risk of incident heart failure among healthy men and women. Nutrition, Metabolism and Cardiovascular Diseases, 722-734. https://doi.org/10.1016/j.numecd.2016.01.003

Background: We aimed to examine the association between chocolate intake and the risk of incident heart failure in a UK general population. We conducted a systematic review and meta-analysis to quantify this association. Methods and results: We used... Read More about Habitual chocolate consumption and the risk of incident heart failure among healthy men and women.

Synthesis and cytotoxicity of thieno[2,3-b]quinoline-2-carboxamide and cycloalkyl[b]thieno[3,2-e]pyridine-2-carboxamide derivatives (2016)
Journal Article
Leung, E., Pilkington, L. I., van Rensburg, M., Jeon, C. Y., Song, M., Arabshahi, H. J., …Barker, D. (2016). Synthesis and cytotoxicity of thieno[2,3-b]quinoline-2-carboxamide and cycloalkyl[b]thieno[3,2-e]pyridine-2-carboxamide derivatives. Bioorganic and Medicinal Chemistry, 24(5), 1142-1154. https://doi.org/10.1016/j.bmc.2016.01.047

Seventy nine derivatives of thieno[2,3-b]quinolines, tetrahydrothieno[2,3-b]quinoline, dihydrocyclopenta[b]thieno[3,2-e]pyridine, cyclohepta[b]thieno[3,2-e]pyridine and hexahydrocycloocta[b]thieno[3,2-e]pyridine were either synthesized or obtained co... Read More about Synthesis and cytotoxicity of thieno[2,3-b]quinoline-2-carboxamide and cycloalkyl[b]thieno[3,2-e]pyridine-2-carboxamide derivatives.

Longitudinal bioimpedance vector plots add little value to fluid management of peritoneal dialysis patients (2016)
Journal Article
Tan, B. K., Yu, Z., Fang, W., Lin, A., Ni, Z., Qian, J., …Davies, S. J. (2016). Longitudinal bioimpedance vector plots add little value to fluid management of peritoneal dialysis patients. Kidney International, 89(2), https://doi.org/10.1038/ki.2015.294

Bioimpedance (BI) has the potential to enable better management of fluid balance, which can worsen over time on peritoneal dialysis (PD) due to loss of residual kidney function and progressive muscle wasting. We undertook a prospective, randomized, o... Read More about Longitudinal bioimpedance vector plots add little value to fluid management of peritoneal dialysis patients.