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Outputs (180)

Application of Nanoparticle Technologies in the Combat against Anti-Microbial Resistance (2018)
Journal Article
Curtis, A., Kumar, M., & Hoskins, C. (2018). Application of Nanoparticle Technologies in the Combat against Anti-Microbial Resistance. Pharmaceutics, https://doi.org/10.3390/pharmaceutics10010011

Anti-microbial resistance is a growing problem that has impacted the world and brought about the beginning of the end for the old generation of antibiotics. Increasingly, more antibiotics are being prescribed unnecessarily and this reckless practice... Read More about Application of Nanoparticle Technologies in the Combat against Anti-Microbial Resistance.

Investigation into Improving the Aqueous Solubility of the Thieno[2,3-b]pyridine Anti-Proliferative Agents (2018)
Journal Article
Reynisson, J. (2018). Investigation into Improving the Aqueous Solubility of the Thieno[2,3-b]pyridine Anti-Proliferative Agents. Molecules, https://doi.org/10.3390/molecules23010145

It is now established that the thieno[2,3-b]pyridines are a potent class of antiproliferatives. One of the main issues encountered for their clinical application is their low water solubility. In order to improve this, two strategies were pursued. Fi... Read More about Investigation into Improving the Aqueous Solubility of the Thieno[2,3-b]pyridine Anti-Proliferative Agents.

Temporal changes in radial access use, associates and outcomes in patients undergoing PCI using rotational atherectomy between 2007 and 2014: results from the British Cardiovascular Intervention Society national database (2018)
Journal Article
Mamas. (2018). Temporal changes in radial access use, associates and outcomes in patients undergoing PCI using rotational atherectomy between 2007 and 2014: results from the British Cardiovascular Intervention Society national database. American Heart Journal, 46-54. https://doi.org/10.1016/j.ahj.2018.01.001

Aims Access site choice for cases requiring rotational atherectomy (PCI-ROTA) is poorly defined. Using the British Cardiovascular Intervention Society PCI database, temporal changes and contemporary associates/outcomes of access site choice for PCI-... Read More about Temporal changes in radial access use, associates and outcomes in patients undergoing PCI using rotational atherectomy between 2007 and 2014: results from the British Cardiovascular Intervention Society national database.

A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and Its Prevention (2018)
Journal Article
(2018). A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and Its Prevention. Oncologist, 84 -96. https://doi.org/10.1634/theoncologist.2017-0263

Chemotherapy-induced alopecia (CIA) is the most visibly distressing side effect of commonly administered chemotherapeutic agents. Because psychological health has huge relevance to lifestyle, diet, and self-esteem, it is important for clinicians to f... Read More about A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and Its Prevention.

Remote regulation of magnetic particle targeted Wnt signalling for bone tissue engineering (2018)
Journal Article
(2018). Remote regulation of magnetic particle targeted Wnt signalling for bone tissue engineering. Nanomedicine: Nanotechnology, Biology and Medicine, 173-184. https://doi.org/10.1016/j.nano.2017.09.008

Wnt signaling is critically involved in the differentiation of human Mesenchymal Stem Cells (hMSC). Wnt proteins therefore have considerable therapeutic value, but are expensive and difficult to produce. UM206 is a synthetic peptide and ligand for th... Read More about Remote regulation of magnetic particle targeted Wnt signalling for bone tissue engineering.

Investigating Heterogeneity of Effects and Associations Using Interaction Terms (2018)
Journal Article
Mamas. (2018). Investigating Heterogeneity of Effects and Associations Using Interaction Terms. Journal of Clinical Epidemiology, 79-83. https://doi.org/10.1016/j.jclinepi.2017.09.012

Effect heterogeneity, the variability of an association or exposure across subgroups, usually warrants further investigation. The aim of this deeper analysis is to identify effect modifiers (or moderators) and quantify their relationship with the exp... Read More about Investigating Heterogeneity of Effects and Associations Using Interaction Terms.