Outputs (187)

Attitudes towards Peritoneal Dialysis among Peritoneal Dialysis and Hemodialysis Medical Directors: Are we preaching to the right choir? (2019)
Journal Article
Shen, J. I., Schreiber, M. J., Zhao, J., Robinson, B. M., Pisoni, R. L., Mehrotra, R., …Perl, J. (2019). Attitudes towards Peritoneal Dialysis among Peritoneal Dialysis and Hemodialysis Medical Directors: Are we preaching to the right choir?. Clinical Journal of the American Society of Nephrology, 14(7), 1067-1070. https://doi.org/10.2215/CJN.01320119

Research letter.

Virtual patient educational programme to teach counselling to clinical pharmacists: development and proof of concept (2019)
Journal Article
White. (2019). Virtual patient educational programme to teach counselling to clinical pharmacists: development and proof of concept. BMJ Simulation and Technology Enhanced Learning, 167-168. https://doi.org/10.1136/+bmjstel-2018-000352

Pharmacist–patient counselling can benefit patients and optimise care, but appropriate training is required. A virtual patient (VP) tool to teach pharmacists non-vitamin K oral anticoagulant counselling was developed; the VP may be used for continuin... Read More about Virtual patient educational programme to teach counselling to clinical pharmacists: development and proof of concept.

Screening a library of approved drugs reveals that prednisolone synergizes with pitavastatin to induce ovarian cancer cell death (2019)
Journal Article
Abed, M., Khanim, F., Richardson, A., & Abdullah, M. (2019). Screening a library of approved drugs reveals that prednisolone synergizes with pitavastatin to induce ovarian cancer cell death. Scientific reports, https://doi.org/10.1038/s41598-019-46102-1

The survival rate for patients with ovarian cancer has changed little in the past three decades since the introduction of platinum-based chemotherapy and new drugs are needed. Statins are drugs used for the treatment and prevention of cardiovascular... Read More about Screening a library of approved drugs reveals that prednisolone synergizes with pitavastatin to induce ovarian cancer cell death.

On the issue of transparency and reproducibility in nanomedicine. (2019)
Other
(2019). On the issue of transparency and reproducibility in nanomedicine

Following our call to join in the discussion over the suitability of implementing a reporting checklist for bio-nano papers, the community responds.

Undergraduate healthcare students need encouragement to use available ethics literature to help inform complex ethical deliberations (2019)
Conference Proceeding
Corfield, L., Stibbs, M., Watkins, C., & Allinson, M. (2019). Undergraduate healthcare students need encouragement to use available ethics literature to help inform complex ethical deliberations.

UBR5 is a novel E3 ubiquitin ligase involved in skeletal muscle hypertrophy and recovery from atrophy. (2019)
Journal Article
(2019). UBR5 is a novel E3 ubiquitin ligase involved in skeletal muscle hypertrophy and recovery from atrophy. The Journal of Physiology, 3727-3749. https://doi.org/10.1113/JP278073

We aimed to investigate a novel and uncharacterised E3 ubiquitin ligase in skeletal muscle atrophy, recovery from atrophy/injury, anabolism and hypertrophy. We demonstrated an alternate gene expression profile for UBR5 versus well characterised E3-li... Read More about UBR5 is a novel E3 ubiquitin ligase involved in skeletal muscle hypertrophy and recovery from atrophy..

A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis. (2019)
Journal Article
(2019). A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis. Nature communications, 2236 - ?. https://doi.org/10.1038/s41467-019-09773-y

Genome-wide association studies (GWAS) have identified more than 50,000 unique associations with common human traits. While this represents a substantial step forward, establishing the biology underlying these associations has proven extremely diffic... Read More about A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis..

Antifungal screening and in silico mechanistic studies of an in-house azole library (2019)
Journal Article
Reynisson. (2019). Antifungal screening and in silico mechanistic studies of an in-house azole library. Chemical Biology & Drug Design, https://doi.org/10.1111/cbdd.13587

Systemic Candida infections pose a serious public health problem with high morbidity and mortality. C. albicans is the major pathogen identified in candidiasis, however non-albicans Candida spp. with antifungal resistance are now more prevalent. Azol... Read More about Antifungal screening and in silico mechanistic studies of an in-house azole library.

Cumulin and FSH cooperate to regulate inhibin B and activin B production by human granulosa-lutein cells in vitro (2019)
Journal Article
Mottershead. (2019). Cumulin and FSH cooperate to regulate inhibin B and activin B production by human granulosa-lutein cells in vitro. Human Reproduction, 408 -408. https://doi.org/10.1093/humrep/34.Supplement_1.1

Meeting abstract, from the 35th Annual Meeting of the European Society of Human Reproduction and Embryology.

Tranexamic acid to improve functional status in adults with spontaneous intracerebral haemorrhage: the TICH-2 RCT. (2019)
Journal Article
Roffe. (2019). Tranexamic acid to improve functional status in adults with spontaneous intracerebral haemorrhage: the TICH-2 RCT. Health Technology Assessment, 1 - 48. https://doi.org/10.3310/hta23350

BACKGROUND:Tranexamic acid reduces death due to bleeding after trauma and postpartum haemorrhage. OBJECTIVE:The aim of the study was to assess if tranexamic acid is safe, reduces haematoma expansion and improves outcomes in adults with spontaneous in... Read More about Tranexamic acid to improve functional status in adults with spontaneous intracerebral haemorrhage: the TICH-2 RCT..