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Outputs (135)

Facile synthesis and biological evaluation of chrysin derivatives (2021)
Journal Article
Omonga, N., Zia, Z., Ghanbour, H., Ragazzon-Smith, A., Foster, H., Hadfield, J., & Ragazzon, P. (2021). Facile synthesis and biological evaluation of chrysin derivatives. Journal of Chemical Research, 1083-1092. https://doi.org/10.1177/17475198211057467

In this paper, novel synthetic methods, including microwave O-alkylation, were used to produce several chrysin derivatives. These compounds were purified, characterised and tested on different cell lines and bacterial strains. From this family, 7-(2,... Read More about Facile synthesis and biological evaluation of chrysin derivatives.

Greater trochanteric pain syndrome: focused shockwave therapy versus an ultrasound guided injection: a randomised control trial (2021)
Journal Article
Heaver, C., Pinches, M., Kuiper, J. H., Thomas, G., Lewthwaite, S., Burston, B. J., & Banerjee, R. D. (2023). Greater trochanteric pain syndrome: focused shockwave therapy versus an ultrasound guided injection: a randomised control trial. Hip International, 33(3), 490-499. https://doi.org/10.1177/11207000211060396

Greater trochanteric pain syndrome (GTPS) is a common problem with an incidence of 1.8–5.6 per 1000 population. Physiotherapy, anti-inflammatories, corticosteroid injections and surgery have all been described in the management of GTPS, with limited,... Read More about Greater trochanteric pain syndrome: focused shockwave therapy versus an ultrasound guided injection: a randomised control trial.

DECELLULARISED PLEURAL PATCHES FOR PROLONGED ALVEOLAR AIR LEAKS (2021)
Presentation / Conference
Vikranth, T., Dale, T., & Forsyth, N. (2021, November). DECELLULARISED PLEURAL PATCHES FOR PROLONGED ALVEOLAR AIR LEAKS. Presented at TERMIS 6th World Congress, Maastricht, Netherlands

Prolonged alveolar air leaks (PALs) as post‐surgical complications to lung resections at an incidence of 26%, is a source of patient morbidity. The gold standard approach to managing PALs is conservative, through extended duration of chest tube drain... Read More about DECELLULARISED PLEURAL PATCHES FOR PROLONGED ALVEOLAR AIR LEAKS.

Impact of the ferrocenyl group on cytotoxicity and KSP inhibitory activity of ferrocenyl monastrol conjugates (2021)
Journal Article
Reynisson, J., Wieczorek-Błauż, A., Kowalczyk, K., Błauż, A., Makal, A., Pawlędzio, S., …Plażuk, D. (2021). Impact of the ferrocenyl group on cytotoxicity and KSP inhibitory activity of ferrocenyl monastrol conjugates. Dalton Transactions, 51(2), 491-508. https://doi.org/10.1039/d1dt03553c

The incorporation of the ferrocenyl moiety into a bioactive molecule may significantly alter the activity of the resulting conjugate. By applying this strategy, we designed ferrocenyl analogs of monastrol - the first low molecular weight kinesin spin... Read More about Impact of the ferrocenyl group on cytotoxicity and KSP inhibitory activity of ferrocenyl monastrol conjugates.

Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM) (2021)
Presentation / Conference
Mason, K., Jordan, K., Achana, F., Bailey, J., Chen, Y., Frisher, M., …Edwards, J. (2021, November). Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM). Poster presented at 2021 SAPC North, Virtual

Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM) (2021)
Presentation / Conference
Mason, K., Jordan, K., Achana, F., Bailey, J., Chen, Y., Frisher, M., …Edwards, J. (2021, November). Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM). Poster presented at 2021 SAPC North, Virtual

Investigation into the Use of Microfluidics in the Manufacture of Metallic Gold-Coated Iron Oxide Hybrid Nanoparticles (2021)
Journal Article
Curtis. (2021). Investigation into the Use of Microfluidics in the Manufacture of Metallic Gold-Coated Iron Oxide Hybrid Nanoparticles. Nanomaterials, 2976 - 2976. https://doi.org/10.3390/nano11112976

Hybrid iron oxide-gold nanoparticles are of increasing interest for applications in nanomedicine, photonics, energy storage, etc. However, they are often difficult to synthesise without experience or 'know-how'. Additionally, standard protocols do no... Read More about Investigation into the Use of Microfluidics in the Manufacture of Metallic Gold-Coated Iron Oxide Hybrid Nanoparticles.

Testosterone Therapy: Increase in Hematocrit is Associated with Decreased Mortality (2021)
Journal Article
(2021). Testosterone Therapy: Increase in Hematocrit is Associated with Decreased Mortality. Androgens, 150 - 159. https://doi.org/10.1089/andro.2021.0019

Objective: Testosterone therapy (TTh) may reduce morbidity/mortality in men with adult-onset testosterone deficiency (TD), though some cardiovascular safety concerns remain. Increased hematocrit (HCT), a recognized effect of therapy, may be associate... Read More about Testosterone Therapy: Increase in Hematocrit is Associated with Decreased Mortality.