Outputs (136)

Outpatient Total Knee Arthroplasty: A Meta-Analysis (2021)
Journal Article

Introduction: Outpatient total knee arthroplasty (TKA) is attracting growing interest. This meta-analysis compared patient reported outcome measures (PROMs), infection, readmission, revision, deep vein thrombosis (DVT), and mortality rates of outpati... Read More about Outpatient Total Knee Arthroplasty: A Meta-Analysis.

Clinical applications of infrared and Raman spectroscopy in the fields of cancer and infectious diseases (2021)
Journal Article

Analytical technologies that can improve disease diagnosis are highly sought after. Current screening/diagnostic tests for several diseases are limited by their moderate diagnostic performance, invasiveness, costly and laborious methodologies or the... Read More about Clinical applications of infrared and Raman spectroscopy in the fields of cancer and infectious diseases.

Strategies for large bone defect reconstruction after trauma, infections or tumour excision: a comprehensive review of the literature (2021)
Journal Article

Large bone defects resulting from musculoskeletal tumours, infections, or trauma are often unable to heal spontaneously. The challenge for surgeons is to avoid amputation, and provide the best functional outcomes. Allograft, vascularized fibular or i... Read More about Strategies for large bone defect reconstruction after trauma, infections or tumour excision: a comprehensive review of the literature.

Investigation of the blood proteome in response to spinal cord injury in rodent models (2021)
Journal Article

STUDY DESIGN: Explanatory and Mechanistic Study OBJECTIVES: A better understanding of the ‘whole-body’ response following spinal cord injury (SCI) is needed to guide future research aimed at developing novel therapeutic interventions and identifying... Read More about Investigation of the blood proteome in response to spinal cord injury in rodent models.

Dystrophin involvement in peripheral circadian SRF signalling (2021)
Journal Article

Absence of dystrophin, an essential sarcolemmal protein required for muscle contraction, leads to the devastating muscle-wasting disease Duchenne muscular dystrophy. Dystrophin has an actin-binding domain, which binds and stabilises filamentous-(F)-a... Read More about Dystrophin involvement in peripheral circadian SRF signalling.

Clerodane Diterpenoids from an Edible Plant Justicia insularis: Discovery, Cytotoxicity, and Apoptosis Induction in Human Ovarian Cancer Cells (2021)
Journal Article

Objectives: The toxicity of chemotherapeutic anticancer drugs is a serious issue in clinics. Drug discovery from edible and medicinal plants represents a promising approach towards finding safer anticancer therapeutics. Justicia insularis T. Anderson... Read More about Clerodane Diterpenoids from an Edible Plant Justicia insularis: Discovery, Cytotoxicity, and Apoptosis Induction in Human Ovarian Cancer Cells.

Slowed-Down Rehabilitation Following Percutaneous Repair of Achilles Tendon Rupture. (2021)
Journal Article

BACKGROUND: Following percutaneous repair of acute Achilles tendon (AT) ruptures, early postoperative weightbearing is advocated; however, it is debatable how aggressive rehabilitation should be. We compared the clinical and functional outcomes in 2... Read More about Slowed-Down Rehabilitation Following Percutaneous Repair of Achilles Tendon Rupture..

Experiencing a virtual patient to practice patient counselling skills (2021)
Journal Article

Introduction Virtual patients (VPs) are a safe and standardised method of simulating clinical environments but few studies have explored health care professional's experiences of learning via a VP. This study explored how users experienced and used a... Read More about Experiencing a virtual patient to practice patient counselling skills.

Bone marrow-derived mesenchymal stem cells combined with gonadotropin therapy restore postnatal oogenesis of chemo-ablated ovaries in rats via enhancing very small embryonic-like stem cells. (2021)
Journal Article

BACKGROUND: Very small embryonic-like stem cells (VSELs) are a rare population within the ovarian epithelial surface. They contribute to postnatal oogenesis as they have the ability to generate immature oocytes and resist the chemotherapy. These cell... Read More about Bone marrow-derived mesenchymal stem cells combined with gonadotropin therapy restore postnatal oogenesis of chemo-ablated ovaries in rats via enhancing very small embryonic-like stem cells..

Skeletal Muscle Possesses an Epigenetic Memory of Exercise: Role of Nucleus Type-Specific DNA Methylation (2021)
Journal Article