Outputs (9)

Cytoplasmic CUG RNA foci are insufficient to elicit key DM1 features (2008)
Journal Article

The genetic basis of myotonic dystrophy type I (DM1) is the expansion of a CTG tract located in the 3' untranslated region of DMPK. Expression of mutant RNAs encoding expanded CUG repeats plays a central role in the development of cardiac disease in... Read More about Cytoplasmic CUG RNA foci are insufficient to elicit key DM1 features.

Variational bayesian generative topographic mapping (2008)
Journal Article

General finite mixture models are powerful tools for the density-based grouping of multivariate i.i.d. data, but they lack data visualization capabilities, which reduces their practical applicability to real-world problems. Generative topographic map... Read More about Variational bayesian generative topographic mapping.

Multiproject–multicenter evaluation of automatic brain tumor classification by magnetic resonance spectroscopy (2008)
Journal Article

JUSTIFICATION: Automatic brain tumor classification by MRS has been under development for more than a decade. Nonetheless, to our knowledge, there are no published evaluations of predictive models with unseen cases that are subsequently acquired in d... Read More about Multiproject–multicenter evaluation of automatic brain tumor classification by magnetic resonance spectroscopy.

Platelet-Derived Growth Factor Stimulates Osteoprotegerin Production in Osteoblastic Cells (2008)
Journal Article

Osteoprotegerin (OPG) is a major regulator of osteoclastogenesis, bone resorption and vascular calcification. OPG is produced by various cell types including mesenchymally derived cells, in particular, osteoblastic cells. Here we show OPG production... Read More about Platelet-Derived Growth Factor Stimulates Osteoprotegerin Production in Osteoblastic Cells.

Advances in clustering and visualization of time series using GTM through time (2008)
Journal Article

Most of the existing research on multivariate time series concerns supervised forecasting problems. In comparison, little research has been devoted to their exploration through unsupervised clustering and visualization. In this paper, the capabilitie... Read More about Advances in clustering and visualization of time series using GTM through time.

Intervertebral disc cells as competent phagocytes in vitro: implications for cell death in disc degeneration (2008)
Journal Article

INTRODUCTION: Apoptosis has been reported to occur in the intervertebral disc. Elsewhere in the body, apoptotic cells are cleared from the system via phagocytosis by committed phagocytes such as macrophages, reducing the chance of subsequent inflamma... Read More about Intervertebral disc cells as competent phagocytes in vitro: implications for cell death in disc degeneration.

Murine mesenchymal stem cells exhibit a restricted repertoire of functional chemokine receptors: comparison with human (2008)
Journal Article

Mesenchymal stem cells (MSCs) are non-haematopoeitic, stromal cells that are capable of differentiating into mesenchymal tissues such as bone and cartilage. They are rare in bone marrow, but have the ability to expand many-fold in culture, and retain... Read More about Murine mesenchymal stem cells exhibit a restricted repertoire of functional chemokine receptors: comparison with human.

The cell culture expansion of bone marrow stromal cells from humans with spinal cord injury: implications for future cell transplantation therapy. (2008)
Journal Article

STUDY DESIGN: Previous studies have shown that transplantation of bone marrow stromal cells (MSCs) in animal models of spinal cord injury (SCI) encourages functional recovery. Here, we have examined the growth in cell culture of MSCs isolated from in... Read More about The cell culture expansion of bone marrow stromal cells from humans with spinal cord injury: implications for future cell transplantation therapy..

Bovine explant model of degeneration of the intervertebral disc (2008)
Journal Article

BACKGROUND: Many new treatments for degeneration of the intervertebral disc are being developed which can be delivered through a needle. These require testing in model systems before being used in human patients. Unfortunately, because of differences... Read More about Bovine explant model of degeneration of the intervertebral disc.