Outputs (161)

Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases (2020)
Journal Article
Mangas-Sanchez, J., Sharma, M., Cosgrove, S. C., Ramsden, J. I., Marshall, J. R., Thorpe, T. W., …Turner, N. J. (in press). Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases. Chemical Science, 11(19), 5052-5057. https://doi.org/10.1039/d0sc02253e

Chiral primary amines are important intermediates in the synthesis of pharmaceutical compounds. Fungal reductive aminases (RedAms) are NADPH-dependent dehydrogenases that catalyse reductive amination of a range of ketones with short-chain primary ami... Read More about Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases.

Developing the Scientific Reporting Skills of Chemistry Students (2020)
Book Chapter
McGarvey, D., Beaumont, K., Capel, N., Hancock, L., Haxton, K., Hollamby, M., …Plana, D. (2020). Developing the Scientific Reporting Skills of Chemistry Students. In On Your Marks: Learner-Focused Feedback Practices and Feedback Literacy. Advance HE

Structural and spectroscopic insights on the coordination chemistry of the rigid heterotopic chelating ligand 1H-pyrazolo[4,3-h]quinoline (2020)
Journal Article
Goodwin, J. W., Kruger, P. E., & Hawes, C. S. (2020). Structural and spectroscopic insights on the coordination chemistry of the rigid heterotopic chelating ligand 1H-pyrazolo[4,3-h]quinoline. Journal of Coordination Chemistry, 74(1-3), 341-360. https://doi.org/10.1080/00958972.2020.1868041

In this work we report the coordination chemistry of a rigid heterotopic ligand 1H-pyrazolo[4,3-h]quinoline HL1 in copper(II) and zinc(II) complexes for the first time, and examine both the structural properties and solution-phase behaviour of these... Read More about Structural and spectroscopic insights on the coordination chemistry of the rigid heterotopic chelating ligand 1H-pyrazolo[4,3-h]quinoline.

Heparin Inhibits Cellular Invasion by SARS-CoV-2: Structural Dependence of the Interaction of the Spike S1 Receptor-Binding Domain with Heparin. (2020)
Journal Article
Mycroft-West, C. J., Su, D., Pagani  , I., Rudd  , T. R., Elli  , S., Gandhi  , N. S., …Skidmore   , M. A. (2020). Heparin Inhibits Cellular Invasion by SARS-CoV-2: Structural Dependence of the Interaction of the Spike S1 Receptor-Binding Domain with Heparin. Thrombosis and Haemostasis, 120(12), 1700 - 1715. https://doi.org/10.1055/s-0040-1721319

The dependence of development and homeostasis in animals on the interaction of hundreds of extracellular regulatory proteins with the peri- and extracellular glycosaminoglycan heparan sulfate (HS) is exploited by many microbial pathogens as a means o... Read More about Heparin Inhibits Cellular Invasion by SARS-CoV-2: Structural Dependence of the Interaction of the Spike S1 Receptor-Binding Domain with Heparin..

Is GW190521 the merger of black holes from the first stellar generations? (2020)
Journal Article
Farrell, E., Groh, J. H., Hirschi, R., Murphy, L., Kaiser, E., Ekström, S., …Meynet, G. (2021). Is GW190521 the merger of black holes from the first stellar generations?. Monthly Notices of the Royal Astronomical Society, 502(1), L40-L44. https://doi.org/10.1093/mnrasl/slaa196

GW190521 challenges our understanding of the late-stage evolution of massive stars and the effects of the pair-instability in particular. We discuss the possibility that stars at low or zero metallicity could retain most of their hydrogen envelope un... Read More about Is GW190521 the merger of black holes from the first stellar generations?.

A ß?Cephei pulsator and a changing orbital inclination in the high-mass eclipsing binary system VV?Orionis (2020)
Journal Article
Southworth, J., Bowman, D. M., & Pavlovski, K. (2021). A ß?Cephei pulsator and a changing orbital inclination in the high-mass eclipsing binary system VV?Orionis. Monthly Notices of the Royal Astronomical Society: Letters, 501(1), L65 - L70. https://doi.org/10.1093/mnrasl/slaa197

We present an analysis of the high-mass eclipsing binary system VV?Ori based on photometry from the TESS satellite. The primary star (B1?V, 9.5?M??) shows ß?Cephei pulsations and the secondary (B7?V, 3.8?M??) is possibly a slowly pulsating B star. We... Read More about A ß?Cephei pulsator and a changing orbital inclination in the high-mass eclipsing binary system VV?Orionis.

The CARMENES search for exoplanets around M dwarfs: LP 714-47 b (TOI 442.01): populating the Neptune desert (2020)
Journal Article
Hellier. (2020). The CARMENES search for exoplanets around M dwarfs: LP 714-47 b (TOI 442.01): populating the Neptune desert. Astronomy and Astrophysics, https://doi.org/10.1051/0004-6361/202038016

We report the discovery of a Neptune-like planet (LP 714-47 b, P = 4.05204 d, mb = 30.8 ± 1.5M?, Rb = 4.7 ± 0.3 R?) located in the “hot Neptune desert”. Confirmation of the TESS Object of Interest (TOI 442.01) was achieved with radial-velocity follow... Read More about The CARMENES search for exoplanets around M dwarfs: LP 714-47 b (TOI 442.01): populating the Neptune desert.

Grids of stellar models with rotation: V. Models from 1.7 to 120 Msun at zero metallicity (2020)
Journal Article
Murphy, L. J., Groh, J. H., Ekström, S., Meynet, G., Pezzotti, C., Georgy, C., …Martinet, S. (2021). Grids of stellar models with rotation: V. Models from 1.7 to 120 Msun at zero metallicity. Monthly Notices of the Royal Astronomical Society, 501(2), 2745-2763. https://doi.org/10.1093/mnras/staa3803

Understanding the nature of the first stars is key to understanding the early universe. With new facilities such as JWST we may soon have the first observations of the earliest stellar populations, but to understand these observations we require deta... Read More about Grids of stellar models with rotation: V. Models from 1.7 to 120 Msun at zero metallicity.

Two Young Planetary Systems around Field Stars with Ages between 20 and 320 Myr from TESS (2020)
Journal Article
Hellier. (2020). Two Young Planetary Systems around Field Stars with Ages between 20 and 320 Myr from TESS. Astronomical Journal, 2 - 2. https://doi.org/10.3847/1538-3881/abba22

Planets around young stars trace the early evolution of planetary systems. We report the discovery and validation of two planetary systems with ages ?300 Myr from observations by the Transiting Exoplanet Survey Satellite (TESS). The Myr old G star TO... Read More about Two Young Planetary Systems around Field Stars with Ages between 20 and 320 Myr from TESS.

Rediscussion Of Eclipsing Binaries. Paper I: The Totally-eclipsing B-type System Zeta Phoenicis (2020)
Journal Article
Taylor. (2020). Rediscussion Of Eclipsing Binaries. Paper I: The Totally-eclipsing B-type System Zeta Phoenicis. Observatory, 140, 247 -262

zeta Phe is a bright binary system containing B6 V and B8 V stars. It has deep total and annular eclipses, a slightly eccentric orbit with a period of I-d.669, apsidal motion, and a third body on a wider orbit. The Transiting Exoplanet Survey Satelli... Read More about Rediscussion Of Eclipsing Binaries. Paper I: The Totally-eclipsing B-type System Zeta Phoenicis.