Outputs (2)

Inhibition of influenza H5N1 invasion by modified heparin derivatives (2015)
Journal Article
Skidmore, M. A., Kajaste-Rudnitski, A., Wells, N. M., Guimond, S. E., Rudd, T. R., Yates, E. A., & Vicenzi, E. Inhibition of influenza H5N1 invasion by modified heparin derivatives. MedChemComm, 6(4), 640-646. https://doi.org/10.1039/c4md00516c

Influenza remains a serious health threat, with resistance to frontline drugs becoming more common, and new treatments urgently sought. One strategy for the inhibition of the attachment of influenza to host cells is to employ chemically modified hepa... Read More about Inhibition of influenza H5N1 invasion by modified heparin derivatives.

Heparin derivatives for the targeting of multiple activities in the inflammatory response. (2015)
Journal Article
Veraldi, N., Hughes, A., Rudd, T., Thomas, H., Edwards, S., Hadfield, L., …Yates, E. (2015). Heparin derivatives for the targeting of multiple activities in the inflammatory response. Carbohydrate Polymers, 400 - 407. https://doi.org/10.1016/j.carbpol.2014.09.079

An attractive strategy for ameliorating symptoms arising from the multi-faceted processes of excessive and/or continual inflammation would be to identify compounds able to interfere with multiple effectors of inflammation. The well-tolerated pharmace... Read More about Heparin derivatives for the targeting of multiple activities in the inflammatory response..