Outputs (19)

Crystal structures of human immune protein FIBCD1 suggest an extended binding site compatible with recognition of pathogen-associated carbohydrate motifs (2023)
Journal Article
Williams, H. M., Moeller, J. B., Burns, I., Schlosser, A., Sorensen, G. L., Greenhough, T. J., …Shrive, A. K. (2023). Crystal structures of human immune protein FIBCD1 suggest an extended binding site compatible with recognition of pathogen-associated carbohydrate motifs. Journal of Biological Chemistry, 105552. https://doi.org/10.1016/j.jbc.2023.105552

Fibrinogen C-domain containing-1 (FIBCD1) is an immune protein proposed to be involved in host recognition of chitin on the surface of pathogens. As FIBCD1 readily binds to acetylated molecules, we have determined the high-resolution crystal structur... Read More about Crystal structures of human immune protein FIBCD1 suggest an extended binding site compatible with recognition of pathogen-associated carbohydrate motifs.

Characterisation of the Structural Requirements for the Immunomodulatory Surfactant Protein D (SP-D) to Bind to Maltose Based Ligands (2022)
Journal Article
Shrive, & Greenhough. (2022). Characterisation of the Structural Requirements for the Immunomodulatory Surfactant Protein D (SP-D) to Bind to Maltose Based Ligands. https://doi.org/10.1164/ajrccm-conference.2022.205.1_MeetingAbstracts.A2609

Lipopolysaccharide recognition by human surfactant protein D (2021)
Presentation / Conference
Neale, W., Madsen, J., Clark, H., Shrive, A., & Greenhough, T. (2021, August). Lipopolysaccharide recognition by human surfactant protein D. Presented at XXV IUCr Congress, Prague, Czech Republic

Structural studies of innate immune proteins (2021)
Presentation / Conference
da Silva, R., Burns, I., Greenhough, T. J., & Shrive, A. K. (2021, August). Structural studies of innate immune proteins. Poster presented at XXV IUCr Congress, Prague, Czech Republic

Structural studies of C-reactive protein (2021)
Presentation / Conference
Collister, S., Neale, W., Littlejohn, J., Greenhough, T., & Shrive, A. (2021, August). Structural studies of C-reactive protein. Poster presented at XXV IUCr Congress, Prague, Czech Republic

Bacterial lipopolysaccharide recognition by surfactant protein D (2021)
Presentation / Conference
Shrive, & Greenhough. (2021, August). Bacterial lipopolysaccharide recognition by surfactant protein D. Presented at XXV IUCr Congress, Prague, Czech Republic

Human surfactant protein D is a collectin and member of the C-type lectin superfamily of proteins that forms an essential part of the mammalian innate immune system. The collectins have been recognised to not only bind to invading pathogens, allowing... Read More about Bacterial lipopolysaccharide recognition by surfactant protein D.

X-ray diffraction data for structure associated with PDB ID: 6ZR0 (2020)
Dataset
Shrive, A., & Greenhough, T. (2020). X-ray diffraction data for structure associated with PDB ID: 6ZR0. [Dataset]. https://doi.org/10.21252/zcfy-cw20

X-ray diffraction data for structure associated with PDB ID: 6ZQR (2020)
Dataset
Shrive, A., & Greenhough, T. (2020). X-ray diffraction data for structure associated with PDB ID: 6ZQR. [Dataset]. https://doi.org/10.21252/r2nx-0425

X-ray diffraction data for structure associated with PDB ID: 6ZQX (2020)
Dataset
Shrive, A., & Greenhough, T. (2020). X-ray diffraction data for structure associated with PDB ID: 6ZQX. [Dataset]. https://doi.org/10.21252/2b3f-9369

X-Ray diffraction data for structure associated with PDB ID: 6ZQY (2020)
Dataset
Shrive, A., & Greenhough, T. (2020). X-Ray diffraction data for structure associated with PDB ID: 6ZQY. [Dataset]. https://doi.org/10.21252/hx7e-rd04