Outputs (1332)

Global Dengue Epidemic Worsens with Record 14 Million Cases and 9,000 Deaths Reported in 2024 (2025)
Journal Article
Haider, N., Hasan, M. N., Onyango, J., Billah, M., Khan, S., Papakonstantinou, D., Paudyal, P., & Asaduzzaman, M. (2025). Global Dengue Epidemic Worsens with Record 14 Million Cases and 9,000 Deaths Reported in 2024. International Journal of Infectious Diseases, 2025(107940), 1-5. https://doi.org/10.1016/j.ijid.2025.107940

Dengue, caused by the dengue virus (DENV), is the fastest-growing mosquito-borne disease worldwide. We utilised monthly data on dengue cases and deaths reported through the World Health Organisation's (WHO) global surveillance system for the period o... Read More about Global Dengue Epidemic Worsens with Record 14 Million Cases and 9,000 Deaths Reported in 2024.

A scoping review of evidence for the effects of seven global deer species on woody vegetation (2025)
Journal Article
Gresham, A., Healey, J. R., Lawrence, P. J., Eichhorn, M. P., & Shannon, G. (2025). A scoping review of evidence for the effects of seven global deer species on woody vegetation. Ecological Solutions and Evidence, 6(2 - April/June 2025), Article e70044. https://doi.org/10.1002/2688-8319.70044

Context: Rapid expansion of deer (Cervidae) populations is a concern for forest ecosystems. Despite extensive reviews on how deer affect forests, variation in effects across deer species has received less attention. A lack of focus on species‐specifi... Read More about A scoping review of evidence for the effects of seven global deer species on woody vegetation.

Management of sacroiliac joint pain: current concepts. (2025)
Journal Article
Migliorini, F., Lucenti, L., Bardazzi, T., Bell, A., Cocconi, F., & Maffulli, N. (2025). Management of sacroiliac joint pain: current concepts. European Journal of Orthopaedic Surgery and Traumatology, 35(1), Article 208. https://doi.org/10.1007/s00590-025-04308-2

Managing sacroiliac joint (SIJ) pain is challenging and unpredictable. There are no internationally accepted recommendations. In light of the lack of global consensus and guidelines and the ongoing advancements in management options, a widely accepte... Read More about Management of sacroiliac joint pain: current concepts..

Translation, cross-cultural adaptation, and validation of the Chinese version of the 4 domain sports prom. (2025)
Journal Article
Sun, Y., Chen, S., Neyret, P., Hutchinson, M., Migliorini, F., Maffulli, N., Górios, C., & Piedade, S. R. (2025). Translation, cross-cultural adaptation, and validation of the Chinese version of the 4 domain sports prom. Journal of Orthopaedic Surgery and Research, 20(1), 1-7. https://doi.org/10.1186/s13018-025-05882-1

Background
This work evaluated and validated the translation and cross-cultural adaptation of 4-Domain Sport PROM (4-DSP) into Chinese, assessing its understandability and reproducibility in all questionnaire domains for Chinese-speaking patients.... Read More about Translation, cross-cultural adaptation, and validation of the Chinese version of the 4 domain sports prom..

Lyophilized MSC-EVs attenuates COVID-19 pathogenesis by regulating the JAK/STAT pathway (2025)
Journal Article
Ebrahim, N., Al Saihati, H. A., Alali, Z., Mahmoud, S. Y. M., Rabaan, A. A., Dessouky, A. A., Salim, R. F., Shamaa, A. A., Abdallah, A. N., Elsherbiny, N. M., Othman, G., Badawy, A. A., Di Leva, G., & Badr, O. A. (2025). Lyophilized MSC-EVs attenuates COVID-19 pathogenesis by regulating the JAK/STAT pathway. Current Stem Cell Research and Therapy, 16(1), Article 244. https://doi.org/10.1186/s13287-025-04284-8

Background: The JAK/STAT signaling pathway plays a crucial role in the release of interferons (IFNs) and the proinflammatory response during SARS-CoV-2 infection, contributing to the cytokine storm characteristic of severe COVID-19 cases. STAT3, a ke... Read More about Lyophilized MSC-EVs attenuates COVID-19 pathogenesis by regulating the JAK/STAT pathway.

Tenogenic Cues Are Biochemically and Environmentally Distinct for Tendon Stem Cells and Mesenchymal/Stromal Stem Cells (2025)
Journal Article
Citro, V., Clerici, M., Della Porta, G., Maffulli, N., Boccaccini, A. R., Dale, T. P., & Forsyth, N. R. (2025). Tenogenic Cues Are Biochemically and Environmentally Distinct for Tendon Stem Cells and Mesenchymal/Stromal Stem Cells. Stem Cells International, 2025, Article 9047956. https://doi.org/10.1155/sci/9047956

Tendon tissue engineering draws on regenerative medicine principles, offering innovative solutions to address the challenges posed by tendon injuries and degenerative conditions. Tendons’ inherent limited regenerative capacity often hinders complete... Read More about Tenogenic Cues Are Biochemically and Environmentally Distinct for Tendon Stem Cells and Mesenchymal/Stromal Stem Cells.

Towards a 'theory of change' for ocean plastics: a socio-oceanography approach to the global challenge of plastic pollution (2025)
Journal Article
Horton, A. A., Henderson, L., Bowyer, C., Courtene-Jones, W., Garrard, S. L., Kulsum, N. M., McKay, D., Manikarachchige, I., Sreekumar, S., & Stanton, T. (2025). Towards a 'theory of change' for ocean plastics: a socio-oceanography approach to the global challenge of plastic pollution. Microplastics and Nanoplastics, 5(1), https://doi.org/10.1186/s43591-025-00127-8

Socio-oceanography is an emerging field which mobilises insights from natural and social sciences to explore the inter-connectedness of societal relationships with the ocean and to adopt a holistic approach to solving key oceanographic and societal c... Read More about Towards a 'theory of change' for ocean plastics: a socio-oceanography approach to the global challenge of plastic pollution.

A modular, reusable biocatalytic flow system for UDP-GlcNAc production (2025)
Journal Article
Roberts, T. L., Dolan, J. P., Miller, G. J., Lima, M. A. D., & Cosgrove, S. C. (2025). A modular, reusable biocatalytic flow system for UDP-GlcNAc production. Reaction Chemistry and Engineering, https://doi.org/10.1039/d5re00127g

We report here the continuous flow synthesis of a high-value sugar nucleotide. Immobilisation of enzymes onto solid carriers permitted transfer of the biocatalysts into packed bed reactors to realise a continuous biocatalytic platform for the synthes... Read More about A modular, reusable biocatalytic flow system for UDP-GlcNAc production.

Intra-articular hyaluronic acid injections for hip osteoarthritis: a level I systematic review (2025)
Journal Article
Migliorini, F., Pilone, M., Mazzoleni, M. G., Schäfer, L., Katusic, D., & Maffulli, N. (2025). Intra-articular hyaluronic acid injections for hip osteoarthritis: a level I systematic review. European Journal of Orthopaedic Surgery and Traumatology, 35(1), 1-12. https://doi.org/10.1007/s00590-025-04292-7

Purpose: The present systematic review investigated the efficacy of intra-articular hyaluronic acid (HA) viscosupplementation for hip osteoarthritis (OA) in patient-reported outcome measures (PROMs) and whether different molecular weights of HA are a... Read More about Intra-articular hyaluronic acid injections for hip osteoarthritis: a level I systematic review.

Crystal structures of human SP-D complexed with synthetic oligosaccharides suggest a role for phosphorylated inner core LPS saccharides in host-pathogen interactions (2025)
Preprint / Working Paper
Williams, H. M., Watson, A., Madsen, J., Clark, H. W., Hood, D. W., Oscarson, S., Greenhough, T. J., & Shrive, A. K. (2025). Crystal structures of human SP-D complexed with synthetic oligosaccharides suggest a role for phosphorylated inner core LPS saccharides in host-pathogen interactions

The innate immune protein human surfactant protein D (SP-D) recognises pathogens in the lungs via binding to carbohydrate surface structures. SP-D has been shown to target gram-negative bacterial lipopolysaccharide via calcium-dependent binding, pref... Read More about Crystal structures of human SP-D complexed with synthetic oligosaccharides suggest a role for phosphorylated inner core LPS saccharides in host-pathogen interactions.