Outputs (1348)

Food safety news events classification via a hierarchical transformer model (2023)
Journal Article
Xiong, S., Tian, W., Batra, V., Fan, X., Xi, L., Liu, H., & Liu, L. (2023). Food safety news events classification via a hierarchical transformer model. Heliyon, 9(7), Article e17806. https://doi.org/10.1016/j.heliyon.2023.e17806

In light of the significance of regulatory authorities and the rising demand for information disclosure, a vast amount of information on food safety news reports is readily accessible on the Internet. The extraction of such information for precise cl... Read More about Food safety news events classification via a hierarchical transformer model.

A transcriptomics-based drug repositioning approach to identify drugs with similar activities for the treatment of muscle pathologies in spinal muscular atrophy (SMA) models (2023)
Other
JM, H., E, M., ER, S., Ö, Ç., P, P.-T., M, D., M, O., LM, W., P, C., MJ, W., DP, T., & M, B. (2023). A transcriptomics-based drug repositioning approach to identify drugs with similar activities for the treatment of muscle pathologies in spinal muscular atrophy (SMA) models

ATR-FTIR spectroscopy of heparin: using multivariate analyses for next-generation quality control (2023)
Thesis
Devlin, A. J. ATR-FTIR spectroscopy of heparin: using multivariate analyses for next-generation quality control. (Thesis). Keele University. https://keele-repository.worktribe.com/output/518613

Heparin is a member of the glycosaminoglycan (GAG) family of naturally occurring, polydisperse, linear polysaccharides. Heparin is a ubiquitous anticoagulant drug, a member of the WHO’s list of vital medicines and the second used drug by weight after... Read More about ATR-FTIR spectroscopy of heparin: using multivariate analyses for next-generation quality control.

Study to determine the rate of kill of anti-leishmanial drugs using a novel bioluminescence-based assay (2023)
Thesis
Freakley, A. L. Study to determine the rate of kill of anti-leishmanial drugs using a novel bioluminescence-based assay. (Thesis). Keele University. https://keele-repository.worktribe.com/output/518051

Leishmaniasis is a neglected tropical disease associated with poverty, deprived socio-economic settings and population displacement, primarily due to conflict. The causative agent are species of Leishmania parasites that are transmitted by sand flies... Read More about Study to determine the rate of kill of anti-leishmanial drugs using a novel bioluminescence-based assay.

The Human Mesenchymal Stem Cell Secretome Directs Macrophage Differentiation in an Oxygen-Dependent Manner (2023)
Preprint / Working Paper
Shephard, M. T., Merkhan, M. M., Dale, T. P., & Forsyth, N. R. The Human Mesenchymal Stem Cell Secretome Directs Macrophage Differentiation in an Oxygen-Dependent Manner

Background
Chronic disease states can share inflammation as an underlying pathology. Macrophages are associated with chronic inflammation; in general, M1 phenotype macrophage activity inhibits cell proliferation and causes tissue damage whilst M2 ma... Read More about The Human Mesenchymal Stem Cell Secretome Directs Macrophage Differentiation in an Oxygen-Dependent Manner.

The Human Mesenchymal Stem Cell Secretome Directs Macrophage Differentiation in an Oxygen-Dependent Manner (2023)
Preprint / Working Paper
Shephard, M. T., Merkhan, M. M., Dale, T. P., & Forsyth, N. R. (2023). The Human Mesenchymal Stem Cell Secretome Directs Macrophage Differentiation in an Oxygen-Dependent Manner

Background
Chronic disease states can share inflammation as an underlying pathology. Macrophages are associated with chronic inflammation; in general, M1 phenotype macrophage activity inhibits cell proliferation and causes tissue damage whilst M2 ma... Read More about The Human Mesenchymal Stem Cell Secretome Directs Macrophage Differentiation in an Oxygen-Dependent Manner.

Timing of dense granule biogenesis in asexual malaria parasites (2023)
Preprint / Working Paper
Vallintine, T., & van Ooij, C. Timing of dense granule biogenesis in asexual malaria parasites

Malaria is an important infectious disease that continues to claim hundreds of thousands of lives annually. The disease is caused by infection of host erythrocytes by apicomplexan parasites of the genus Plasmodium. The parasite contains three differe... Read More about Timing of dense granule biogenesis in asexual malaria parasites.

Occurrence of tuberculosis among people exposed to cattle in Bangladesh (2023)
Journal Article
Sarkar, S., Haider, N., Islam, A., Hossain, M. B., Hossain, K., Mafij Uddin, M. K., Rahman, A., Ahmed, S. S. U., Banu, S., Rahim, Z., Heffelfinger, J. D., & Zeidner, N. (2023). Occurrence of tuberculosis among people exposed to cattle in Bangladesh. Veterinary Medicine and Science, 9(4), 1923-1933. https://doi.org/10.1002/vms3.1178

Background
Tuberculosis (TB) has been an important public health concern in Bangladesh. The most common cause of human TB is Mycobacterium tuberculosis, while bovine TB is caused by Mycobacterium bovis.

Objective
The objective of this study was... Read More about Occurrence of tuberculosis among people exposed to cattle in Bangladesh.

Temporal variation in spider trophic interactions is explained by the influence of weather on prey communities, web building and prey choice (2023)
Journal Article
Cuff, J. P., Windsor, F. M., Tercel, M. P., Bell, J. R., Symondson, W. O., & Vaughan, I. P. (2023). Temporal variation in spider trophic interactions is explained by the influence of weather on prey communities, web building and prey choice. Ecography, 2023(7), https://doi.org/10.1111/ecog.06737

Generalist invertebrate predators are sensitive to weather conditions, but the relationship between their trophic interactions and weather is poorly understood. This study investigates how weather affects the identity and frequency of spider trophic... Read More about Temporal variation in spider trophic interactions is explained by the influence of weather on prey communities, web building and prey choice.

Optimized protocol for in vivo affinity purification proteomics and biochemistry using C. elegans (2023)
Journal Article
Desbois, M., Pak, J. S., Opperman, K. J., Giles, A. C., & Grill, B. (2023). Optimized protocol for in vivo affinity purification proteomics and biochemistry using C. elegans. STAR Protocols, 4(2), https://doi.org/10.1016/j.xpro.2023.102262

We present an optimized protocol for in vivo affinity purification proteomics and biochemistry using the model organism C. elegans. We describe steps for target tagging, large-scale culture, affinity purification using a cryomill, mass spectrometry a... Read More about Optimized protocol for in vivo affinity purification proteomics and biochemistry using C. elegans.