Continuous Flow Liquid-Liquid Separation Using a Computer-Vision Control System: The Bromination of Enaminones with N-Bromosuccinimide

Cooper, D; O'Brien, M

Abstract

Incorporating open-source software components (Python, OpenCV), a computer-vision system was used to control the interface level in a gravity-based inline liquid–liquid separation device. This was used in the continuous flow bromination of a series of enaminone substrates. The main byproduct of the reaction, succinimide, was efficiently extracted into the aqueous stream, providing clean products without the need for further purification.

Citation

Cooper, D., & O'Brien, M. (2016). Continuous Flow Liquid-Liquid Separation Using a Computer-Vision Control System: The Bromination of Enaminones with N-Bromosuccinimide. SYNLETT, 164 - 168. https://doi.org/10.1055/s-0035-1560975

• Acceptance Date: May 19, 2016
• Publication Date: May 19, 2016
• Journal: SYNLETT
• Print ISSN: 0936-5214
• Publisher: Thieme Gruppe
• Pages: 164 - 168
• DOI: https://doi.org/10.1055/s-0035-1560975
• Keywords: continuous flow; liquid-liquid separation; bromination; enaminone; open source; computer-vision; OpenCV; Python
• Publisher URL: https://doi.org/10.1055/s-0035-1560975