Talking about Risk, UncertaintieS of Testing IN Genetics (TRUSTING): development and evaluation of an educational programme for healthcare professionals about BRCA1 & BRCA2 testing

Fallowfield, Lesley; Solis-Trapala; Solis-Trapala, Ivonne; Starkings, Rachel; May, Shirley; Matthews, Lucy; Eccles, Diana; Evans, D. Gareth; Turnbull, Clare; Crawford, Gillian; Jenkins, Valerie

Abstract

Background Mainstreaming of germline testing demands that all healthcare professionals have good communication skills, but few have genetic testing and counselling experience. We developed and evaluated educational workshops-Talking about Risk & UncertaintieS of Testing IN Genetics (TRUSTING). Contents included: presentations and exercises, an interview with a geneticist about BRCA testing, screening and prevention implications, filmed interactions between surgeons, a genetic counsellor and geneticists with a fictitious family (proband had a BRCA2 pathogenic variant with triple-negative breast cancer, her older sister-BRCA2 heterozygous, and cousin-negative for BRCA2 variant). Methods Twenty-one surgeons, 5 oncologists, 18 nurses and 9 genetic counsellors participated. Knowledge (18 item MCQ), communication skills (responses to 6 questions from proband and relatives) and self-confidence (discussing 9 genetic testing issues) were assessed pre- and post workshop. Results Knowledge scores improved significantly post workshop (mean change = 7.06; 95% confidence interval (CI) 6.37-7.74; P < 0.001), as did communication (mean change = 5.38; 95% CI 4.37-6.38; P < 0.001) and self-confidence (P < 0.001). Discussion Healthcare professionals' knowledge and self-confidence when discussing the risks and uncertainties in genetics are often poor. TRUSTING workshops significantly enhanced attendees' navigation of communication difficulties encountered and will be rolled out more widely.

Citation

Fallowfield, L., Solis-Trapala, Solis-Trapala, I., Starkings, R., May, S., Matthews, L., …Jenkins, V. (2022). Talking about Risk, UncertaintieS of Testing IN Genetics (TRUSTING): development and evaluation of an educational programme for healthcare professionals about BRCA1 &amp; BRCA2 testing. British Journal of Cancer, 127, 1116-1122. https://doi.org/10.1038/s41416-022-01871-x

• Journal Article Type: Article
• Acceptance Date: May 26, 2022
• Online Publication Date: Jun 17, 2022
• Publication Date: Oct 5, 2022
• Journal: British Journal of Cancer
• Print ISSN: 0007-0920
• Publisher: Cancer Research UK
• Peer Reviewed: Peer Reviewed
• Volume: 127
• Pages: 1116-1122
• DOI: https://doi.org/10.1038/s41416-022-01871-x
• Keywords: Breast cancer, cancer
• Publisher URL: https://www.nature.com/articles/s41416-022-01871-x