Complex, high-risk percutaneous coronary intervention types, trends, and in-hospital outcomes among different age groups: An insight from a national registry.

Rashid, Muhammad; Shamkhani, Warkaa; Mamas, Mamas

Abstract

BACKGROUND: Complex, high-risk percutaneous coronary intervention (PCI) (CHiP) is increasingly being undertaken in octogenarians. However, limited data exist on CHiP types, trends, and outcomes in the octogenarian. METHODS: This is a retrospective cohort study from a national registry dataset on CHiP undertaken in patients with stable angina in England and Wales (January 2006 and December 2017) according to three age groups (group 1 [G1]:?<?65 years; group 2 [G2]: 65-79 years; and group 3 [G3]: =80 years). RESULTS: Of 424,290 elective PCI procedures, 138,831 (33.0%) were CHiP [G1: 46,832 (33.7%); G2: 59,544 (42.9%); G3: 32,455 (23.4%)]. Among CHiP types, chronic total occlusion (CTO) (49.2%), prior coronary artery bypass graft (CABG) (30.4%), and severe vascular calcification (21.8%) were common in G1; prior CABG (42.9%), CTO (32.9%), and severe vascular calcifications (27%) were common in G2; prior CABG (15.8%), severe vascular calcification (15.5%), and chronic renal failure (11.1%) were common CHiP among the octogenarians. The older age groups had higher adjusted odds (aOR) for adverse outcomes [G2: mortality, aOR 1.7, 95% confidence interval (CI): (1.3-2.3); major bleeding, aOR 1.3, 95% CI (1.1-1.5); MACCE, aOR 1.2, 95% CI (1.0-1.3); G3: mortality, aOR 2.6, 95%CI (1.9-3.6); major bleeding, aOR 1.4, 95% CI (1.1-1.7); MACCE, aOR 1.3, 95% CI (1.1-1.5)]. CONCLUSION: There were significant differences in the types of CHiP cases undertaken and clinical outcomes across age groups.

Citation

Rashid, M., Shamkhani, W., & Mamas, M. (2022). Complex, high-risk percutaneous coronary intervention types, trends, and in-hospital outcomes among different age groups: An insight from a national registry. Catheterization & Cardiovascular Interventions, 100(5), 711-720. https://doi.org/10.1002/ccd.30366

• Journal Article Type: Article
• Acceptance Date: Aug 9, 2022
• Online Publication Date: Sep 2, 2022
• Publication Date: Sep 2, 2022
• Journal: Catheterization and Cardiovascular Interventions
• Print ISSN: 1522-1946
• Publisher: Wiley
• Volume: 100
• Issue: 5
• Pages: 711-720
• DOI: https://doi.org/10.1002/ccd.30366
• Keywords: Cardiology and Cardiovascular Medicine, Radiology, Nuclear Medicine and imaging, General Medicine
• Publisher URL: https://onlinelibrary.wiley.com/doi/10.1002/ccd.30366