Temporal trends in utilization and outcomes of transcatheter aortic valve replacement in different races: an analysis of the national inpatient sample

Ullah, Waqas; Al-Khadra, Yasser; Mir, Tanveer; Darmoch, Fahed; Pacha, Homam M.; Sattar, Yasar; Ijioma, Nketchi; Mohamed, Mohamed O.; Kwok, Chun S.; Asfour, Abedelrahim I.; Kapadia, Samir; Rizik, David; Zehr, Kenton; Mamas, Mamas A.; Alraies, M. Chadi

Abstract

AIM: We sought to determine the racial and ethnical disparities in the delivery of TAVR and to evaluate the in-hospital outcomes and utilization of TAVR stratified by patient ethnicity. METHOD: Using a national inpatient sample database between 2011 and 2015, we identified all adult patients who had TAVR. Races were identified and white race was set as control. Multiple logistic regression analysis was performed for the primary outcome of in-hospital mortality. RESULTS: Out of 58?174 patients who underwent TAVR, 50?809 (87.3%) were white, 2327 (4.0%) were black, 2311 (4.0%) were Hispanic, 640 (1.1%) Asian, 105 (0.2%) Native American and 1982 (3.4%) of other ethnicities. We found a statistically significant linear uptrend in the utilization of TAVR in patients of all races between the years 2011 and 2015. White, black, Hispanic and Native American patients had a downward linear trend for mortality during the studied years (P?=?0.005 for all). Black patients had lower in-hospital mortality [2.8 vs. 3.6%, odds ratio (OR)?=?0.62; 95% confidence interval (CI) 0.44, 0.81 P?<?0.001] compared with white patients, whereas Hispanic patients and Native Americans had higher in-hospital mortality compared with white patients (4.5% OR 1.26; 95% CI 1.01, 1.56 P?=?0.041), (9.5% OR 4.44; 95% CI 2.25, 8.77 P?<?0.001), respectively. CONCLUSION: Overall, TAVR utilization is associated with lower mortality. There is a rising trend in utilization of TAVR in the black population with a significantly favorable mortality trend compared with the white population.

Citation

Ullah, W., Al-Khadra, Y., Mir, T., Darmoch, F., Pacha, H. M., Sattar, Y., Ijioma, N., Mohamed, M. O., Kwok, C. S., Asfour, A. I., Kapadia, S., Rizik, D., Zehr, K., Mamas, M. A., & Alraies, M. C. (2021). Temporal trends in utilization and outcomes of transcatheter aortic valve replacement in different races: an analysis of the national inpatient sample. Journal of Cardiovascular Medicine, 22(7), 586 - 593. https://doi.org/10.2459/JCM.0000000000001172

• Journal Article Type: Article
• Acceptance Date: Jan 31, 2021
• Online Publication Date: Feb 26, 2021
• Publication Date: Jul 1, 2021
• Journal: J Cardiovasc Med (Hagerstown)
• Print ISSN: 1558-2027
• Electronic ISSN: 1558-2035
• Publisher: Lippincott, Williams & Wilkins
• Volume: 22
• Issue: 7
• Pages: 586 - 593
• DOI: https://doi.org/10.2459/JCM.0000000000001172
• Keywords: mortality; race; transcatheter aortic valve replacement
• Public URL: https://keele-repository.worktribe.com/output/426803