Influence of the aggregation, concentration, and viscosity on the nanomagnetism of iron oxide nanoparticle colloids for magnetic hyperthermia

Cabrera, David; Camarero, Julio; Ortega, Daniel; Teran, Francisco J.

Abstract

Iron oxide nanoparticles have become ubiquitous in many biomedical applications, acting as core elements in an increasing number of therapeutic and diagnostic modalities. These applications mainly rely on their static and dynamic magnetic properties, through which they can be remotely actuated. However, little attention has been paid to understand the variation of the magnetic response of nanoparticles inside cells or tissues, despite of the remarkable changes reported to date. In this article, we provide some hints to analyze the influence of the biological matrix on the magnetism of iron oxide nanoparticles. To this aim, we propose the assessment of the heating efficiency of magnetic colloids against nanoparticle aggregation, concentration, and viscosity in order to mimic the fate of nanoparticles upon cell internalization.

• Journal Article Type: Article
• Acceptance Date: Feb 17, 2015
• Online Publication Date: Mar 6, 2015
• Publication Date: 2015-03
• Deposit Date: Jun 12, 2023
• Journal: Journal of Nanoparticle Research
• Print ISSN: 1388-0764
• Electronic ISSN: 1572-896X
• Publisher: Springer Verlag
• Peer Reviewed: Peer Reviewed
• Volume: 17
• Issue: 3
• DOI: https://doi.org/10.1007/s11051-015-2921-9
• Keywords: Condensed Matter Physics; General Materials Science; Modeling and Simulation; General Chemistry; Atomic and Molecular Physics, and Optics; Bioengineering
• Additional Information: Nanomagnetism; Magnetic iron oxide nanoparticles; Magnetic hyperthermia; Dipolar interactions; Aggregation; Viscosiy; Cell internalization; Bioinspired nanomaterials