COVID-19 exit strategy during vaccine implementation: a balance between social distancing and herd immunity

Daher-Nashif, Suhad; Al-Anany, Rania; Ali, Menatalla; Erradi, Khadija; Farag, Elmoubasher; Abdallah, Abdallah M.; Emara, Mohamed M.

Abstract

There is a sound empirical basis for hypofractionation in radiotherapy for breast cancer. This article reviews the radiobiological implications of hypofractionation in breast cancer derived from a series of clinical trials that began when 50 Gy in 25 fractions over 5 weeks was commonplace. These trials led first to 40 Gy in 15 fractions over 3 weeks and, subsequently, to 26 Gy in five fractions over 1 week being adopted as standards of care for many patients prescribed whole- or partial-breast radiotherapy after primary surgery.

• Journal Article Type: Article
• Acceptance Date: Apr 5, 2022
• Online Publication Date: Jun 20, 2022
• Publication Date: 2022-09
• Deposit Date: Jun 16, 2023
• Journal: Archives of Virology
• Print ISSN: 0304-8608
• Electronic ISSN: 1432-8798
• Publisher: Springer Verlag
• Peer Reviewed: Peer Reviewed
• Volume: 167
• Issue: 9
• Pages: 1773-1783
• DOI: https://doi.org/10.1007/s00705-022-05495-7
• Keywords: General Medicine
• Additional Information: Received: 20 October 2021; Accepted: 5 April 2022; First Online: 20 June 2022; : ; : All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest or non-financial interest in the subject matter or materials discussed in this manuscript.