Plan Quality of Modern Radiotherapy Delivery Techniques in Left-Sided Breast Cancer: An Analysis Stratified by Consensus Target Delineation Guidelines

Chufal, K. S.; Bhatt, C. P.; Bajpai, R.; Chowdhary, R. L.; Pahuja, A. K.

Abstract

Purpose/Objective(s)
This study investigates the performance of treatment planning methods stratified by established target delineation guidelines in patients undergoing whole-breast radiotherapy after breast conservation surgery, based on an objective plan quality assessment scale.

Materials/Methods
Treatment planning CT datasets of ten patients with left-sided breast cancer were randomly selected, and target delineation for intact breast was performed using Tangent (RTOG 0413), ESTRO and RTOG guidelines. Elective nodal volumes were not delineated as part of this analysis. Plan Quality Metric (PQM) scoring of each goal was defined and communicated to the planner before commencing treatment planning. There were 12 sub-components of the PQM, grouped into PTV and OAR categories, each having a

Results
A total of 450 plans were generated for the entire cohort and 90 plans were selected based on PQM score and minimum acceptance criteria. Total PQM score of plans for Tangent and ESTRO were comparable for FiF and IMRT techniques (FiF vs IMRT for Tangent: 68.33 ± 6.52 vs 69.61 ± 5.54, p = 0.637; FiF vs IMRT for ESTRO: 72.80 ± 5.27 vs 75.60 ± 5.89, p = 0.304), and were also significantly higher compared to VMAT (p < 0.001 for all comparisons). Total PQM score of plans for RTOG revealed that IMRT

Conclusion
FiF and IMRT planning techniques are best suited for ESTRO or Tangent delineations. IMRT also yields better results with RTOG delineation.

Citation

Ahmad, I., Chufal, K. S., Bhatt, C. P., Bajpai, R., Miller, A., Chowdhary, R. L., …Gairola, M. (2020, October). Plan Quality of Modern Radiotherapy Delivery Techniques in Left-Sided Breast Cancer: An Analysis Stratified by Consensus Target Delineation Guidelines. Poster presented at Global Oncology: The ASTRO Annual Meeting

• Presentation Conference Type: Poster
• Conference Name: Global Oncology: The ASTRO Annual Meeting
• Start Date: Oct 24, 2020
• End Date: Oct 28, 2020
• Deposit Date: Jun 19, 2023
• Publisher: Elsevier
• DOI: https://doi.org/10.1016/j.ijrobp.2020.07.1163
• Keywords: Cancer Research; Radiology, Nuclear Medicine and imaging; Oncology; Radiation
• Public URL: https://keele-repository.worktribe.com/output/488908
• Additional Information: This article is maintained by: Elsevier; Article Title: Plan Quality of Modern Radiotherapy Delivery Techniques in Left-Sided Breast Cancer: An Analysis Stratified by Consensus Target Delineation Guidelines; Journal Title: International Journal of Radiation Oncology*Biology*Physics; CrossRef DOI link to publisher maintained version: https://doi.org/10.1016/j.ijrobp.2020.07.1163; Content Type: simple-article; Copyright: Copyright © 2020 Published by Elsevier Inc.