Abstract 15368: Index Admission and Thirty-day Readmission Outcomes of Cancer Patients Presenting With Stemi

Osman, Mohammed; Benjamin, Mina M; Balla, Sudarshan; Kheiri, Babikir; Bianco, Christopher; sengupta, Partho; Daggubati, Ramesh; malla, midhun; Liu, Stephen; Mamas, Mamas; Patel, Brijesh

Abstract

Introduction: National-level data of cancer patients’ readmissions after a ST-segment elevation myocardial infarction (STEMI) are lacking.

Objectives: The primary aim of this study was to describe rates and causes of 30-day readmissions in this population.

Methods: Among patients who were admitted with STEMI in the United States National Readmission Database (NRD) from October 2015-December 2017, we identified patients with the diagnosis of active breast, colorectal, lung or prostate cancer. The primary endpoint was 30-day unplanned readmission rate. Secondary endpoints included in-hospital outcomes during the index admission and causes of readmissions. A propensity score model was used to compare the outcomes of cancer and no cancer patients.

Results: A total of 385,522 patients were included in the current analysis (Cancer= 5,956, No Cancer=379,566). After propensity score matching, 23,880 patients were compared (Cancer=5,949, No Cancer=17,931). Cancer patients had higher 30-day readmission (19% vs 14%, p<0.01). The most common causes for readmission among cancer patients were cardiac (31%), followed by infectious (21%), hematological and oncological (17%), respiratory (4%), stroke (4%) and renal (3%). During the first readmission, cancer patients had higher in-hospital mortality (15% vs 7%; p<0.01) and bleeding complications (31% vs 21%; p<0.01). In multivariate logistic regression, cancer status (OR 1.5, 95% CI 1.2-1.6, p<0.01) was an independent predictor for 30-day readmission.

Conclusions: About one in five cancer patients presenting with STEMI will be readmitted within 30 days. Cancer patients’ 30-day readmissions are still predominantly cardiac-related but with a higher proportion of admissions for infectious, cancer-related and bleeding and than those without cancer.

Citation

Osman, M., Benjamin, M. M., Balla, S., Kheiri, B., Bianco, C., sengupta, P., Daggubati, R., malla, M., Liu, S., Mamas, M., & Patel, B. (2020). Abstract 15368: Index Admission and Thirty-day Readmission Outcomes of Cancer Patients Presenting With Stemi. Circulation, 142(Suppl_3), https://doi.org/10.1161/circ.142.suppl_3.15368

• Journal Article Type: Article
• Acceptance Date: Nov 12, 2020
• Online Publication Date: Nov 12, 2020
• Publication Date: Nov 17, 2020
• Deposit Date: Jun 23, 2023
• Journal: Circulation
• Print ISSN: 0009-7322
• Electronic ISSN: 1524-4539
• Publisher: American Heart Association
• Peer Reviewed: Peer Reviewed
• Volume: 142
• Issue: Suppl_3
• DOI: https://doi.org/10.1161/circ.142.suppl_3.15368
• Keywords: Physiology (medical); Cardiology and Cardiovascular Medicine
• Public URL: https://keele-repository.worktribe.com/output/503832