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The human glutathione S-transferases. Immunohistochemical studies of the developmental expression of Alpha- and Pi-class isoenzymes in liver.

Hiley, C; Fryer, A; Bell, J; Hume, R; Strange, R C

Authors

C Hiley

J Bell

R Hume

R C Strange



Abstract

Immunohistochemical studies of the developmental expression of the Alpha- and Pi-class glutathione S-transferases in human liver have shown that the Pi enzyme is expressed in bile-duct epithelium and some hepatocytes but not in haematopoietic cells. This locus is down-regulated during gestation in hepatocytes but not in epithelium. The enzymes of the Alpha set were also found in only some hepatocytes, and it appears that many cells express neither these nor the Pi forms.

Citation

Hiley, C., Fryer, A., Bell, J., Hume, R., & Strange, R. C. (1988). The human glutathione S-transferases. Immunohistochemical studies of the developmental expression of Alpha- and Pi-class isoenzymes in liver. Biochemical Journal, 254(1), 255–259. https://doi.org/10.1042/bj2540255

Journal Article Type Article
Online Publication Date Aug 15, 1988
Publication Date 1988-08
Deposit Date Feb 8, 2024
Journal The Biochemical Journal
Print ISSN 0264-6021
Electronic ISSN 1470-8728
Publisher Portland Press
Peer Reviewed Peer Reviewed
Volume 254
Issue 1
Pages 255–259
DOI https://doi.org/10.1042/bj2540255
Publisher URL https://portlandpress.com/biochemj/article-abstract/254/1/255/24089/The-human-glutathione-S-transferases?redirectedFrom=fulltext
PMID 3178749