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Social Vulnerability and Cardiovascular-related Mortality Among Older Adults In the United States.

Khan Minhas, Abdul Mannan; Kobo, Ofer; Mamas, Mamas A; Al-Kindi, Sadeer G; Abushamat, Layla A; Nambi, Vijay; Michos, Erin D; Ballantyne, Christie; Abramov, Dmitry


Abdul Mannan Khan Minhas

Ofer Kobo

Sadeer G Al-Kindi

Layla A Abushamat

Vijay Nambi

Erin D Michos

Christie Ballantyne

Dmitry Abramov


The association of social vulnerability and cardiovascular disease- related mortality in older adults has not been well characterized. The Centers for Disease Control and Prevention database was evaluated to examine the relationship between county-level Social Vulnerability Index (SVI) and age adjusted cardiovascular disease-related mortality rates (AAMRs) in adults aged 65 and above in the United States between 2016 and 2020. 3139 counties in the United States were analyzed. The cardiovascular disease-related AAMRs increased in a stepwise manner from 1 (least vulnerable) to 4th SVI quartiles; (AAMR of 2423, CI 2417-2428; 2433, CI 2429-2437; 2516, CI 2513-2520; 2660, CI 2657-2664). Similar trends among AAMRs were noted based on sex, all race and ethnicity categories, and among urban and rural regions. Higher AAMR ratios between the highest and lowest SVI quartiles, implying greater relative associations of SVI on mortality rates, were seen among Hispanic individuals (1.52, CI 1.49-1.55), Non-Hispanic-Asian and Pacific Islander individuals (1.32, CI 1.29-1.52), Non-Hispanic- American Indian or Alaskan Native individuals (1.43, CI 1.37-1.50), and rural counties (1.21, 1.20-1.21). Social vulnerability as measures by the SVI was associated with cardiovascular disease -related mortality in older adults, with the association being particularly prominent in ethnic minority patients and rural counties. [Abstract copyright: Copyright © 2023. Published by Elsevier Inc.]

Journal Article Type Article
Acceptance Date Oct 16, 2023
Online Publication Date Oct 23, 2023
Deposit Date Nov 14, 2023
Journal The American journal of medicine
Print ISSN 0002-9343
Electronic ISSN 1555-7162
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 137
Issue 2
Pages 122-127
Keywords Racial Disparities, Cardiovascular Disease, Mortality, social vulnerability