Skip to main content

Research Repository

Advanced Search

Aneurysmal bone cysts: A UK wide tumor center experience

Bavan, Luckshman; Eastley, Nicholas; Stevenson, Jonathan; Mifsud, Maximillian; Bayliss, Lee; Mahmoud, Shady; Baker, Gavin; Cusick, Laurence; Nail, Rebecca; Rankin, Kenneth; Crooks, Sophie; Cool, Paul; Williams, Derfel; Kandarakis, Georgios; Duncan, Roderick; Kothari, Alpesh


Luckshman Bavan

Nicholas Eastley

Jonathan Stevenson

Maximillian Mifsud

Lee Bayliss

Shady Mahmoud

Gavin Baker

Laurence Cusick

Rebecca Nail

Kenneth Rankin

Sophie Crooks

Derfel Williams

Georgios Kandarakis

Roderick Duncan

Alpesh Kothari


Background and Objectives
This multicenter retrospective series of consecutive extra-spinal aneurysmal bone cysts aims to identify risk factors for treatment failure.

Aneurysmal bone cysts treated within seven collaborating centers with over 12-months follow-up were eligible for inclusion. Survival analyses were performed to identify variables associated with recurrence using log-rank tests and Cox proportional hazard regression.

One hundred and fifteen (M:F 60:55) patients were included. Median age at presentation was 13 years and median follow-up was 27 months. Seventy-five patients underwent surgical curettage and 27% of these required further intervention for recurrence. Of the 30 patients who underwent biopsy with limited percutaneous curettage as initial procedure, 47% required no further treatment. Patients under 13 years (log-rank p = 0.006, HR 2.3, p = 0.011) and those treated who had limited curettage (log-rank p = 0.001, HR 2.7, p = 0.002) had a higher risk of recurrence/persistence.

There is a high risk of recurrence following surgical treatment for aneurysmal bone cysts and this risk is higher in young patients. However, the cyst heals in a substantial number of patients who have a limited curettage at the time of biopsy.


Bavan, L., Eastley, N., Stevenson, J., Mifsud, M., Bayliss, L., Mahmoud, S., …Kothari, A. (in press). Aneurysmal bone cysts: A UK wide tumor center experience. Journal of Surgical Oncology, 129(3), 601-608.

Journal Article Type Article
Acceptance Date Oct 15, 2023
Online Publication Date Nov 15, 2023
Deposit Date Nov 27, 2023
Journal Journal of Surgical Oncology
Print ISSN 0022-4790
Electronic ISSN 1096-9098
Publisher Wiley
Peer Reviewed Peer Reviewed
Volume 129
Issue 3
Pages 601-608
Keywords Oncology, General Medicine, Surgery