Knee osteoarthritis, joint laxity and PROMs following conservative management versus surgical reconstruction for ACL rupture: a meta-analysis

Migliorini, Filippo; Oliva, Francesco; Eschweiler, Joerg; Torsiello, Ernesto; Hildebrand, Frank; Maffulli, Nicola

Abstract

AbstractIntroductionPatients whose rupture of the anterior cruciate ligament (ACL) can be managed conservatively or undergo reconstruction surgery.Source of dataCurrent scientific literature published in Web of Science, PubMed and Scopus.Areas of agreementSeveral studies published by July 2022 compare surgical and conservative management following ACL rupture. The latest evidence suggests that surgical management may expose patients to an increased risk of early-onset knee osteoarthritis (OA).Areas of controversyThe state of art does not recommend a systematic ACL reconstruction to all patients who tore their ACL. After the initial trauma, surgical reconstruction may produce even greater damage to the intra-articular structures compared to conservative management.Growing pointsThe state of art does not recommend systematic surgical reconstruction to all patients who tore their ACL. The present study compared surgical reconstruction versus conservative management for primary ACL ruptures in terms of joint laxity, patient reported outcome measures (PROMs) and rate of osteoarthritis.Areas timely for developing researchACL reconstruction provides significant improvement in joint laxity compared to conservative management, but is associated with a significantly greater rate of knee osteoarthritis, despite similar results at PROM assessment.

Citation

Migliorini, F., Oliva, F., Eschweiler, J., Torsiello, E., Hildebrand, F., & Maffulli, N. (2023). Knee osteoarthritis, joint laxity and PROMs following conservative management versus surgical reconstruction for ACL rupture: a meta-analysis. British Medical Bulletin, 145(1), 72-87. https://doi.org/10.1093/bmb/ldac029

• Journal Article Type: Article
• Acceptance Date: Oct 11, 2022
• Online Publication Date: Nov 21, 2022
• Publication Date: Apr 5, 2023
• Deposit Date: Jan 11, 2024
• Journal: British Medical Bulletin
• Print ISSN: 0007-1420
• Publisher: Oxford University Press
• Peer Reviewed: Peer Reviewed
• Volume: 145
• Issue: 1
• Pages: 72-87
• DOI: https://doi.org/10.1093/bmb/ldac029
• Keywords: General Medicine