Cardiovascular Health Metrics Differ Between Individuals With and Without Cancer.

Kobo, Ofer; Abramov, Dmitry; Fiuza, Manuela; Chew, Nicholas W S; Ng, Cheng Han; Parwani, Purvi; Menezes, Miguel Nobre; Thavendiranathan, Paaladinesh; Mamas, Mamas A

Abstract

Although individuals with cancer experience high rates of cardiovascular morbidity, there are limited data on the potential differences in cardiovascular health (CVH) metrics between individuals with and without cancer. The National Health and Nutrition Examination Survey between 2015 and 2020 was queried to evaluate the prevalence of health metrics that comprise the American Heart Association Life's Essential 8 construct of cardiovascular health among adult individuals with and without cancer in the United States. Health metric scores were also evaluated according to important patient demographics including age, sex, race and ethnicity, and socioeconomic status. Among 4370 participants representing >180 million US adults, 9.4% had a history of cancer. Individuals with cancer had lower overall cardiovascular health scores (67.1 versus 69.1, <0.001) compared with individuals without cancer. Among individual components of the cardiovascular health score, those with cancer had better health scores on key behaviors including physical activity, diet, and sleep compared with those without cancer, although variation was noted based on age. Higher scores on these modifiable health behaviors among those with cancer compared with those without cancer were noted in older individuals, in White individuals compared with other races and ethnicities, and in individuals with higher socioeconomic status. We highlight important variations in simple cardiovascular health metrics among individuals with cancer compared with individuals without cancer and demonstrate differences among health metrics based on age, race and ethnicity, and socioeconomic status. These findings may explain ongoing racial, ethnic, and socioeconomic status disparities in the cancer population and provide a framework for optimizing cardiovascular health among individuals with cancer.

Citation

Kobo, O., Abramov, D., Fiuza, M., Chew, N. W. S., Ng, C. H., Parwani, P., …Mamas, M. A. (in press). Cardiovascular Health Metrics Differ Between Individuals With and Without Cancer. Journal of the American Heart Association, 12(23), Article e030942. https://doi.org/10.1161/JAHA.123.030942

• Journal Article Type: Article
• Acceptance Date: Oct 31, 2023
• Online Publication Date: Dec 1, 2023
• Deposit Date: Dec 18, 2023
• Journal: Journal of the American Heart Association
• Publisher: Wiley Open Access
• Peer Reviewed: Peer Reviewed
• Volume: 12
• Issue: 23
• Article Number: e030942
• DOI: https://doi.org/10.1161/JAHA.123.030942
• Keywords: Risk Factors, Health Status, Aged, Humans, Adult, Neoplasms - epidemiology, Nutrition Surveys, Quality Indicators, Health Care, cardiovascular disease, Cardiovascular Diseases - diagnosis, health metrics, cancer, United States - epidemiology