Synthesis of Oxazolidinones by a Hypervalent Iodine Mediated Cyclization of N‐Allylcarbamates

Das, Mirdyul; Rodríguez, Arantxa; Lo, Pui Kin Tony; Moran, Wesley J.

Abstract

The preparation of oxazolidinones by the hypervalent iodine mediated cyclization of allylcarbamates is described. A versatile range of substrates can be converted into substituted oxazolidinones primed for further transformations. Derivatization of the products at both ends is demonstrated. A preliminary attempt at the enantioselective formation of an oxazolidinone using a chiral iodane is also presented.

Citation

Das, M., Rodríguez, A., Lo, P. K. T., & Moran, W. J. (2021). Synthesis of Oxazolidinones by a Hypervalent Iodine Mediated Cyclization of N‐Allylcarbamates. Advanced synthesis & catalysis, 363(6), 1646-1650. https://doi.org/10.1002/adsc.202001451

• Journal Article Type: Article
• Acceptance Date: Feb 1, 2021
• Online Publication Date: Feb 4, 2021
• Publication Date: Mar 16, 2021
• Deposit Date: Feb 20, 2024
• Journal: Advanced Synthesis & Catalysis
• Print ISSN: 1615-4150
• Electronic ISSN: 1615-4169
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 363
• Issue: 6
• Pages: 1646-1650
• DOI: https://doi.org/10.1002/adsc.202001451
• Keywords: General Chemistry
• Additional Information: Received: 2020-11-20; Published: 2021-02-04