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Outputs (2202)

Textile based medical devices and their role in sustainable health systems (2024)
Thesis
Morris, H. V. Textile based medical devices and their role in sustainable health systems. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/956321

The field of medical textiles is one of the fastest growing areas within the technical textiles sector of the textile industry. Part of this expansion is because of advances in technology, such as nanotechnology, electrospinning, and the ability to i... Read More about Textile based medical devices and their role in sustainable health systems.

ColMA ‐based bioprinted 3D scaffold allowed to study tenogenic events in human tendon stem cells (2024)
Journal Article
Cortella, G., Lamparelli, E. P., Ciardulli, M. C., Lovecchio, J., Giordano, E., Maffulli, N., & Della Porta, G. (in press). ColMA ‐based bioprinted 3D scaffold allowed to study tenogenic events in human tendon stem cells. Bioengineering and Translational Medicine, 1-15. https://doi.org/10.1002/btm2.10723

The advent of bioprinting has enabled the creation of precise three‐dimensional (3D) cell cultures suitable for biomimetic in vitro models. In this study, we developed a novel protocol for 3D printing methacrylated collagen (ColMa, or PhotoCol®) comb... Read More about ColMA ‐based bioprinted 3D scaffold allowed to study tenogenic events in human tendon stem cells.

Antidepressants for pain management in adults with chronic pain: a network meta-analysis (2024)
Journal Article
Birkinshaw, H., Friedrich, C., Cole, P., Eccleston, C., Serfaty, M., Stewart, G., …Pincus, T. (2024). Antidepressants for pain management in adults with chronic pain: a network meta-analysis. Health Technology Assessment, 28(62), 1-155. https://doi.org/10.3310/mkrt2948

Background
Chronic pain is common and costly. Antidepressants are prescribed to reduce pain. However, there has not been a network meta-analysis examining all antidepressants across all chronic pain conditions, so effectiveness and safety for most a... Read More about Antidepressants for pain management in adults with chronic pain: a network meta-analysis.

Hypervalent iodine mediated cyclization of bishomoallylamides to prolinols (2024)
Journal Article
Butt, S. E., Kepski, K., Sotiropoulos, J.-M., & Moran, W. J. (2024). Hypervalent iodine mediated cyclization of bishomoallylamides to prolinols. Beilstein Journal of Organic Chemistry, 20, 2455-2460. https://doi.org/10.3762/bjoc.20.209

A change in mechanism was observed in the hypervalent iodine mediated cyclization of N-alkenylamides when the carbon chain between the alkene and the amide increased from two to three atoms. In the latter case, cyclization at the amide nitrogen to fo... Read More about Hypervalent iodine mediated cyclization of bishomoallylamides to prolinols.

Platelet Lysate and Osteoarthritis of the Knee: A Review of Current Clinical Evidence (2024)
Journal Article
Gupta, A., & Maffulli, N. (2024). Platelet Lysate and Osteoarthritis of the Knee: A Review of Current Clinical Evidence. Pain and Therapy, 13(6), 1377-1386. https://doi.org/10.1007/s40122-024-00661-y

Introduction: Osteoarthritis (OA) of the knee affects millions of people with sizable socioeconomic burden. Conventional treatment modalities are prioritized, turning to surgical intervention only when they have failed. However, these traditional mod... Read More about Platelet Lysate and Osteoarthritis of the Knee: A Review of Current Clinical Evidence.

Characterizing Biomechanics of Limbal Niche Using Vibrational Optical Coherence Elastography (2024)
Journal Article
Dimmock, R., Zhang, Y., Butt, G., Rauz, S., Huang, Z., & Yang, Y. (in press). Characterizing Biomechanics of Limbal Niche Using Vibrational Optical Coherence Elastography. Journal of Biophotonics, Article e202400172. https://doi.org/10.1002/jbio.202400172

The limbal niche is an adult source of epithelial stem cells which regenerate the cornea epithelium. The architecture and biomechanical properties of the limbus have previously been demonstrated to change due to aging and disease. This study aims to... Read More about Characterizing Biomechanics of Limbal Niche Using Vibrational Optical Coherence Elastography.

MSC–extracellular vesicle microRNAs target host cell-entry receptors in COVID-19: in silico modeling for in vivo validation (2024)
Journal Article
Al Saihati, H. A., Dessouky, A. A., Salim, R. F., Elgohary, I., El-Sherbiny, M., Ali, F. E. M., …Ebrahim, N. (in press). MSC–extracellular vesicle microRNAs target host cell-entry receptors in COVID-19: in silico modeling for in vivo validation. Stem Cell Research and Therapy, 15(1), 1-22. https://doi.org/10.1186/s13287-024-03889-9

Background: Coronavirus disease 2019 (COVID-19) has created a global pandemic with significant morbidity and mortality. SARS-CoV-2 primarily infects the lungs and is associated with various organ complications. Therapeutic approaches to combat COVID-... Read More about MSC–extracellular vesicle microRNAs target host cell-entry receptors in COVID-19: in silico modeling for in vivo validation.

V2 Ovine UC-MSCs Revised Manuscript (2024)
Journal Article
Perry, J., Mennan, C., Cool, P., McCarthy, H., Newell, K., Hopkins, T., …Roberts, S. (in press). V2 Ovine UC-MSCs Revised Manuscript. Cartilage,