Improving alkynyl(aryl)iodonium salts: 2-anisyl as a superior aryl group

Moran, Wesley; Hamnett, David

Abstract

The majority of alkynyl(aryl)iodonium salts reported in the literature are derived from iodobenzene. This article describes the effects of varying this iodoarene building block on the synthesis, reactivity and stability of these salts. Two procedures to synthesize a variety of known and novel alkynyl(aryl)iodonium tosylates directly from the iodoarene are reported. In the reactions of these salts, those derived from 2-iodoanisole gave superior results than the others tested in every reaction. Isothermal microcalorimetry indicated that these novel salts were significantly more stable and less prone to decomposition than all of the other derivatives.

Citation

Moran, W., & Hamnett, D. (2014). Improving alkynyl(aryl)iodonium salts: 2-anisyl as a superior aryl group. Organic and Biomolecular Chemistry, 12(24), https://doi.org/10.1039/c4ob00556b

• Journal Article Type: Article
• Acceptance Date: May 6, 2014
• Online Publication Date: May 6, 2014
• Publication Date: 2014
• Deposit Date: Mar 11, 2024
• Journal: Organic and Biomolecular Chemistry
• Print ISSN: 1477-0520
• Publisher: Royal Society of Chemistry
• Peer Reviewed: Peer Reviewed
• Volume: 12
• Issue: 24
• DOI: https://doi.org/10.1039/c4ob00556b
• Public URL: https://keele-repository.worktribe.com/output/764016
• Publisher URL: https://pubs.rsc.org/en/content/articlelanding/2014/ob/c4ob00556b