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Effect of a 2-week interruption in methotrexate treatment on COVID-19 vaccine response in people with immune-mediated inflammatory diseases (VROOM study): a randomised, open label, superiority trial

Abhishek, Abhishek; Peckham, Nicholas; Pade, Corinna; Gibbons, Joseph M; Cureton, Lucy; Francis, Anne; Barber, Vicki; Williams, Jennifer A E; Appelbe, Duncan; Eldridge, Lucy; Julier, Patrick; Altmann, Daniel M; Bluett, James; Brooks, Tim; Coates, Laura C; Rombach, Ines; Semper, Amanda; Otter, Ashley; Valdes, Ana M; Nguyen-Van-Tam, Jonathan S; Williams, Hywel C; Boyton, Rosemary J; McKnight, Áine; Cook, Jonathan A; Pande, Ira; Tang, Ting Seng; Tran, Gui; Layton, Alison; Price, Elizabeth; Whittam, Lindsay; Venkatachalam, Srinivasan; Huws, Gwenan; Pratt, Arthur; Reynolds, Nick J; Youngstein, Taryn; Walsh, David A; Joseph, Theresa; Mathew, Rengi; Oikonomou, Stamatios; Gwynne, Catherine; Crowder, Rory; Saravanan, Vadivelu; Mustafa, Alaa; Tacu, Cristina; George, Emmanuel; Batty, Thomas; Soni, Anushka; Horton, Sarah; Gaffney, Karl; Gullick, Nicola; Lapin, Agnieszka; Bingham, Sarah; Madan, Ayesha; Holroyd, Chris; Lwin, May; Khalid, Salema; Green, Mike; Hunt, Laura; Alcorn, Nicola; Ellis, Rob;...

Authors

Abhishek Abhishek

Nicholas Peckham

Corinna Pade

Joseph M Gibbons

Lucy Cureton

Anne Francis

Vicki Barber

Jennifer A E Williams

Duncan Appelbe

Lucy Eldridge

Patrick Julier

Daniel M Altmann

James Bluett

Tim Brooks

Laura C Coates

Ines Rombach

Amanda Semper

Ashley Otter

Ana M Valdes

Jonathan S Nguyen-Van-Tam

Hywel C Williams

Rosemary J Boyton

Áine McKnight

Jonathan A Cook

Ira Pande

Ting Seng Tang

Gui Tran

Alison Layton

Elizabeth Price

Lindsay Whittam

Srinivasan Venkatachalam

Gwenan Huws

Arthur Pratt

Nick J Reynolds

Taryn Youngstein

David A Walsh

Theresa Joseph

Rengi Mathew

Stamatios Oikonomou

Catherine Gwynne

Rory Crowder

Vadivelu Saravanan

Alaa Mustafa

Cristina Tacu

Emmanuel George

Thomas Batty

Anushka Soni

Sarah Horton

Karl Gaffney

Nicola Gullick

Agnieszka Lapin

Sarah Bingham

Ayesha Madan

Chris Holroyd

May Lwin

Salema Khalid

Mike Green

Laura Hunt

Nicola Alcorn

Rob Ellis

Ala Hassan

Karen Douglas

Gen Nen Ho

Kirsty Levasseur

John Pradeep

Ceril Rhys-Dillon

Catrin Jones



Citation

Abhishek, A., Peckham, N., Pade, C., Gibbons, J. M., Cureton, L., Francis, A., …Jones, C. (2024). Effect of a 2-week interruption in methotrexate treatment on COVID-19 vaccine response in people with immune-mediated inflammatory diseases (VROOM study): a randomised, open label, superiority trial. The Lancet Rheumatology, 6(2), e92-e104. https://doi.org/10.1016/s2665-9913%2823%2900298-9

Journal Article Type Article
Acceptance Date Dec 12, 2023
Online Publication Date Dec 12, 2023
Publication Date 2024-02
Deposit Date Mar 22, 2024
Journal The Lancet Rheumatology
Print ISSN 2665-9913
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 6
Issue 2
Pages e92-e104
DOI https://doi.org/10.1016/s2665-9913%2823%2900298-9
Keywords Immunology; Immunology and Allergy; Rheumatology
Public URL https://keele-repository.worktribe.com/output/784200
Publisher URL https://www.sciencedirect.com/science/article/pii/S2665991323002989?via%3Dihub
Additional Information This article is maintained by: Elsevier; Article Title: Effect of a 2-week interruption in methotrexate treatment on COVID-19 vaccine response in people with immune-mediated inflammatory diseases (VROOM study): a randomised, open label, superiority trial; Journal Title: The Lancet Rheumatology; CrossRef DOI link to publisher maintained version: https://doi.org/10.1016/S2665-9913(23)00298-9; CrossRef DOI link to the associated document: https://doi.org/10.1016/S2665-9913(23)00306-5; Content Type: article; Copyright: © 2023 The Author(s). Published by Elsevier Ltd.