DR Mirna Maarabouni m.m.maarabouni@keele.ac.uk
GNB2L1 (guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1)
Mourtada-Maarabouni, M
Authors
Abstract
GNB2L1 encodes a cytosolic protein with a molecular mass of approximatively 35 kDa (317 amino acids). The protein has seven internal Trp-Asp 40 (WD40 domain) repeats. The WD40 repeats of RACK1/GNB2L1 are predicted to form a seven-bladed propeller structure, where each blade is composed of a four-stranded anti-parallel beta-sheet. The highly conserved WD repeat sequence of RACK1/GNB2L1 is found in a number of eukaryotic proteins and is implicated in a wide variety of functions including adaptor/regulatory modules in signal transduction, premRNA processing and cytoskeleton assembly.
Citation
Mourtada-Maarabouni, M. GNB2L1 (guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1). Atlas of Genetics and Cytogenetics in Oncology and Haematology, https://doi.org/10.4267/2042/38501
Journal Article Type | Article |
---|---|
Deposit Date | May 15, 2024 |
Journal | Atlas of Genetics and Cytogenetics in Oncology and Haematology |
Peer Reviewed | Peer Reviewed |
Issue | 2 |
DOI | https://doi.org/10.4267/2042/38501 |
Public URL | https://keele-repository.worktribe.com/output/828244 |
Additional Information | https://www.researchgate.net/publication/48272222_GNB2L1_guanine_nucleotide_binding_protein_G_protein_beta_polypeptide_2-like_1 |
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