GNB2L1 (guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1)

Mourtada-Maarabouni, M

Abstract

GNB2L1 encodes a cytosolic protein with a molecular mass of approximatively 35 kDa (317 amino acids). The protein has seven internal Trp-Asp 40 (WD40 domain) repeats. The WD40 repeats of RACK1/GNB2L1 are predicted to form a seven-bladed propeller structure, where each blade is composed of a four-stranded anti-parallel beta-sheet. The highly conserved WD repeat sequence of RACK1/GNB2L1 is found in a number of eukaryotic proteins and is implicated in a wide variety of functions including adaptor/regulatory modules in signal transduction, premRNA processing and cytoskeleton assembly.

Citation

Mourtada-Maarabouni, M. GNB2L1 (guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1). Atlas of Genetics and Cytogenetics in Oncology and Haematology, https://doi.org/10.4267/2042/38501

• Journal Article Type: Article
• Deposit Date: May 15, 2024
• Journal: Atlas of Genetics and Cytogenetics in Oncology and Haematology
• Peer Reviewed: Peer Reviewed
• Issue: 2
• DOI: https://doi.org/10.4267/2042/38501
• Public URL: https://keele-repository.worktribe.com/output/828244
• Additional Information: https://www.researchgate.net/publication/48272222_GNB2L1_guanine_nucleotide_binding_protein_G_protein_beta_polypeptide_2-like_1