Susanne Arnold
Recurrent patellar dislocation: personalised therapy or operative treatment? The REPPORT randomised trial protocol
Arnold, Susanne; Haque, Aminul; Aujla, Manjit; Barrows, Raegan; Beard, David; Chandler, Craig; Chandler, Elizabeth; Ellard, David R; Eldridge, Jonathan; Ferreira, Manuela; Foster, Nadine E; Griffin, James; Mason, James; Mandalia, Vipul; Parsons, Helen; Ray, Georgina; Stewart, Kimberley; Thompson, Peter; Underwood, Martin; Whitehouse, Michael R; Zanganeh, Mandana; Metcalfe, Andrew; Smith, Toby
Authors
Aminul Haque
Manjit Aujla
Raegan Barrows
David Beard
Craig Chandler
Elizabeth Chandler
David R Ellard
Jonathan Eldridge
Manuela Ferreira
Nadine E Foster
James Griffin
James Mason
Vipul Mandalia
Helen Parsons
Georgina Ray
Kimberley Stewart
Peter Thompson
Martin Underwood
Michael R Whitehouse
Mandana Zanganeh
Andrew Metcalfe
Toby Smith
Abstract
Introduction: Recurrent patellar dislocation is a debilitating musculoskeletal condition, affecting mainly adolescents and adults under the age of 30. It can persist for many decades, causing pain and cartilage and soft-tissue damage, potentially leading to osteoarthritis. Recurrent patellar dislocation can be managed with physiotherapy or surgery. However, it is not known which treatment is most effective. Methods and analysis: Recurrent Patellar Dislocation: Personalised Therapy or Operative Treatment (REPPORT) is a pragmatic, multicentre, two-arm, superiority, randomised controlled trial. It will compare the clinical and cost-effectiveness of an initial management strategy of personalised, phased and progressive rehabilitation, termed personalised knee therapy versus surgery for recurrent patellar dislocation. The trial’s target sample size is 276 participants who will be recruited from approximately 20 sites across the UK. Participants will be randomly allocated to the two treatment groups via a central computer-based minimisation system. Treatment allocation will be in a 1:1 ratio, stratified by age, presence of patella alta and recruitment site. The primary outcome is participant-reported function using the Knee injury and Osteoarthritis Outcome 4-domain score at 18 months post randomisation. Health economic evaluation will be conducted from a healthcare system and personal social services perspective. Secondary outcome data including patellar instability, health utility, work/education status, satisfaction with social roles and treatment, health resource use and adverse events will be collected at 6, 12, 18 and 24 months. Analysis will be on an intention-to-treat basis and reported in-line with the Consolidated Standards of Reporting Trials statement. Ethics and dissemination: The trial was approved by the East Midlands—Nottingham 2 Research Ethics Committee on 30 March 2023. Results will be disseminated via peer-reviewed publications, presentations at national and international conferences, in lay summaries, and using the REPPORT website and social media channels. Trial registration number: ISRCTN17972668.
Citation
Arnold, S., Haque, A., Aujla, M., Barrows, R., Beard, D., Chandler, C., …Smith, T. (2024). Recurrent patellar dislocation: personalised therapy or operative treatment? The REPPORT randomised trial protocol. BMJ Open, 14(8), https://doi.org/10.1136/bmjopen-2024-090233
Journal Article Type | Article |
---|---|
Acceptance Date | Jul 18, 2024 |
Online Publication Date | Aug 21, 2024 |
Publication Date | Aug 21, 2024 |
Deposit Date | Sep 2, 2024 |
Publicly Available Date | Sep 2, 2024 |
Journal | BMJ Open |
Publisher | BMJ Publishing Group |
Peer Reviewed | Peer Reviewed |
Volume | 14 |
Issue | 8 |
DOI | https://doi.org/10.1136/bmjopen-2024-090233 |
Keywords | SURGERY, Physical Therapy Modalities, Randomized Controlled Trial, TRAUMA MANAGEMENT, Orthopaedic & trauma surgery |
Public URL | https://keele-repository.worktribe.com/output/890018 |
Publisher URL | https://bmjopen.bmj.com/content/14/8/e090233 |
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Recurrent patellar dislocation: personalised therapy or operative treatment? The REPPORT randomised trial protocol
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Copyright Statement
This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
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