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All Outputs (354)

Understanding the management of heart failure with preserved ejection fraction: a qualitative multiperspective study. (2020)
Journal Article
Chew-Graham. (2020). Understanding the management of heart failure with preserved ejection fraction: a qualitative multiperspective study. British Journal of General Practice (BJGP), 880-889. https://doi.org/10.3399/bjgp20X713477

BACKGROUND: About half of all people with heart failure have heart failure with preserved ejection fraction (HFpEF), in which the heart is stiff. This type of heart failure is more common in older people with a history of hypertension, obesity, and d... Read More about Understanding the management of heart failure with preserved ejection fraction: a qualitative multiperspective study..

Does anxiety moderate the effectiveness of mirtazapine in patients with treatment-resistant depression? A secondary analysis of the MIR trial. (2020)
Journal Article
Chew-Graham. (2020). Does anxiety moderate the effectiveness of mirtazapine in patients with treatment-resistant depression? A secondary analysis of the MIR trial. Journal of Psychopharmacology, 1342 - 1349. https://doi.org/10.1177/0269881120965939

BACKGROUND: There is a lack of evidence to guide treatment of comorbid depression and anxiety. Preliminary evidence suggests mirtazapine may be effective in treating patients with both depression and anxiety symptoms. METHODS: We undertook a secondar... Read More about Does anxiety moderate the effectiveness of mirtazapine in patients with treatment-resistant depression? A secondary analysis of the MIR trial..

RCGP Research Paper of the Year 2019: impact of COVID-19 (2020)
Journal Article
Chew-Graham, C. (2020). RCGP Research Paper of the Year 2019: impact of COVID-19. British Journal of General Practice (BJGP), 70(701), 602-603. https://doi.org/10.3399/bjgp20x713777

The Research Paper of the Year (RPY), awarded by the Royal College of General Practitioners (RCGP), gives recognition to an individual or group of researchers who have undertaken and published an exceptional piece of research relating to general prac... Read More about RCGP Research Paper of the Year 2019: impact of COVID-19.

Access to psychological support for young people following stoma surgery: Exploring patients’ and clinicians’ perspectives (2020)
Journal Article
Polidano, K., Chew-Graham, C., Farmer, A., & Saunders, B. (2020). Access to psychological support for young people following stoma surgery: Exploring patients’ and clinicians’ perspectives. Qualitative Health Research, 31(3), 535-549. https://doi.org/10.1177/1049732320972338

Psychological problems are common among people with inflammatory bowel disease (IBD) following stoma surgery. However, the ways in which stoma-related psychological needs are identified and addressed in healthcare settings remain unexplored. In this... Read More about Access to psychological support for young people following stoma surgery: Exploring patients’ and clinicians’ perspectives.

Acute myocardial infarction in several mental illness: a nationwide analysis of prevalence, management strategies and outcomes (2020)
Journal Article
Mohamed, M., Rashid, M., Farooq, S., Siddiqui, N., Parwani, P., Shiers, D., …Mamas, M. (2020). Acute myocardial infarction in several mental illness: a nationwide analysis of prevalence, management strategies and outcomes. European Heart Journal, 41(Supplement_2), https://doi.org/10.1093/ehjci/ehaa946.3146

Background Severe mental illness (SMI) is associated with an increased risk of cardiovascular disease and mortality. However, it is unclear whether SMI patients are just as likely to receive guideline-recommended therapy for AMI as those without men... Read More about Acute myocardial infarction in several mental illness: a nationwide analysis of prevalence, management strategies and outcomes.

Finding the 'right' GP: a qualitative study of the experiences of people with long-COVID (2020)
Journal Article
Kingstone, T., Taylor, A. K., O'Donnell, C. A., Atherton, H., Blane, D. N., & Chew-Graham, C. (2020). Finding the 'right' GP: a qualitative study of the experiences of people with long-COVID. British Journal of General Practice Open (BJGP Open), 4(5), https://doi.org/10.3399/bjgpopen20X101143

BACKGROUND: An unknown proportion of people who had an apparently mild COVID-19 infection continue to suffer with persistent symptoms, including chest pain, shortness of breath, muscle and joint pains, headaches, cognitive impairment ('brain fog'), a... Read More about Finding the 'right' GP: a qualitative study of the experiences of people with long-COVID.

The experiences of general practitioner partners living with distress: An interpretative phenomenological analysis (2020)
Journal Article
Spiers, J., Buszewicz, M., Chew-Graham, C. A., & Riley, R. (2020). The experiences of general practitioner partners living with distress: An interpretative phenomenological analysis. Journal of Health Psychology, 25(10-11), 1439-1449. https://doi.org/10.1177/1359105318758860

Doctors, including general practitioners, experience higher levels of mental illness than the general population. General practitioners who are partners in their practices may face heightened stress. In total, 10 general practitioner partners living... Read More about The experiences of general practitioner partners living with distress: An interpretative phenomenological analysis.

A relational analysis of an invisible illness: A meta-ethnography of people with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and their support needs (2020)
Journal Article
Pilkington, K., Ridge, D. T., Igwesi-Chidobe, C., Chew-Graham, C. A., Little, P., Babatunde, O., …Cheshire, A. (2020). A relational analysis of an invisible illness: A meta-ethnography of people with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and their support needs. Social Science and Medicine, 265, Article 113369. https://doi.org/10.1016/j.socscimed.2020.113369

Chronic fatigue syndrome (CFS)/myalgic encephalomyelitis (ME) is indicated by prolonged, medically unexplained fatigue (amongst other symptoms), not alleviated by rest, and causing substantial disability. There are limited treatments on offer, which... Read More about A relational analysis of an invisible illness: A meta-ethnography of people with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and their support needs.

Temporal Trends in Pregnancy‐Associated Stroke and Its Outcomes Among Women With Hypertensive Disorders of Pregnancy (2020)
Journal Article
Wu, P., Jordan, K. P., Chew‐Graham, C. A., Coutinho, T., Lundberg, G. P., Park, K. E., …Mamas, M. A. (2020). Temporal Trends in Pregnancy‐Associated Stroke and Its Outcomes Among Women With Hypertensive Disorders of Pregnancy. Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, 9(15), https://doi.org/10.1161/JAHA.120.016182

Background Stroke is a serious complication of hypertensive disorders of pregnancy (HDP), with potentially severe and long-term sequelae. However, the temporal trends, predictors and outcomes of stroke in women with HDP at delivery remain unknown.... Read More about Temporal Trends in Pregnancy‐Associated Stroke and Its Outcomes Among Women With Hypertensive Disorders of Pregnancy.

Does anxiety moderate the efficacy of mirtazapine in patients with treatment resistant depression? A secondary analysis of the mir trial (2020)
Presentation / Conference
Rifkin-Zybutz, R., Macneill, S., Dickens, C., Campbell, J., Chew-Graham, C., Peters, T., …Kessler, D. (2020, July). Does anxiety moderate the efficacy of mirtazapine in patients with treatment resistant depression? A secondary analysis of the mir trial. Poster presented at 28th European Congress of Psychiatry, Madrid, Spain

Introduction: Mirtazapine has been shown to be effective in treating patients with both depression and anxiety symptoms.1 This has not been examined in primary care. Objectives: We examined whether anxiety moderated the effect of mirtazapine com... Read More about Does anxiety moderate the efficacy of mirtazapine in patients with treatment resistant depression? A secondary analysis of the mir trial.

Markers of dementia-related health in primary care electronic health records. (2020)
Journal Article
Campbell, P., Rathod-Mistry, T., Marshall, M., Bailey, J., Chew-Graham, C. A., Croft, P., …Jordan, K. P. (2020). Markers of dementia-related health in primary care electronic health records. Aging and Mental Health, 25(8), https://doi.org/10.1080/13607863.2020.1783511

Objectives Identifying routinely recorded markers of poor health in patients with dementia may help treatment decisions and evaluation of earlier outcomes in research. Our objective was to determine whether a set of credible markers of dementia-rela... Read More about Markers of dementia-related health in primary care electronic health records..

Routine laboratory surveillance of antimicrobial resistance in community-acquired urinary tract infections adequately informs prescribing policy in England (2020)
Journal Article
Watts, V., Brown, B., Ahmed, M., Charlett, A., Chew-Graham, C., Cleary, P., …Welfare, W. (2020). Routine laboratory surveillance of antimicrobial resistance in community-acquired urinary tract infections adequately informs prescribing policy in England. JAC-ANTIMICROBIAL RESISTANCE, 2(2), Article ARTN dlaa022. https://doi.org/10.1093/jacamr/dlaa022

Objectives To assess whether resistance estimates obtained from sentinel surveillance for antimicrobial resistance (AMR) in community-acquired urinary tract infections (UTIs) differ from routinely collected laboratory community UTI data. Methods... Read More about Routine laboratory surveillance of antimicrobial resistance in community-acquired urinary tract infections adequately informs prescribing policy in England.

The challenge of pain identification, assessment, and management in people with dementia: a qualitative study (2020)
Journal Article
Bullock, L., Chew-Graham, C., Bedson, J., Bartlam, B., & Campbell, P. (2020). The challenge of pain identification, assessment, and management in people with dementia: a qualitative study. British Journal of General Practice Open (BJGP Open), 4(2), 1-14. https://doi.org/10.3399/bjgpopen20X101040

Background Painful conditions are common in older adults, including people with dementia. The symptoms associated with dementia (for example, diminished language capacity, memory impairment, and behavioural changes), however, may lead to the suboptim... Read More about The challenge of pain identification, assessment, and management in people with dementia: a qualitative study.

Development and validation of the DIabetes Severity SCOre (DISSCO) in 139 626 individuals with type 2 diabetes: a retrospective cohort study. (2020)
Journal Article
Mamas, Chew-Graham, & Mallen. (2020). Development and validation of the DIabetes Severity SCOre (DISSCO) in 139 626 individuals with type 2 diabetes: a retrospective cohort study. BMJ Open Diabetes Research and Care, https://doi.org/10.1136/bmjdrc-2019-000962

OBJECTIVE: Clinically applicable diabetes severity measures are lacking, with no previous studies comparing their predictive value with glycated hemoglobin (HbA1c). We developed and validated a type 2 diabetes severity score (the DIabetes Severity SC... Read More about Development and validation of the DIabetes Severity SCOre (DISSCO) in 139 626 individuals with type 2 diabetes: a retrospective cohort study..

How do older adults understand and manage distress? A qualitative study (2020)
Journal Article
Moult, A., Kingstone, T., & Chew-Graham, C. (2020). How do older adults understand and manage distress? A qualitative study. BMC Family Practice, 21, -. https://doi.org/10.1186/s12875-020-01152-7

BACKGROUND: Distress is an expected emotional response to a negative life event. Experiences common in later life may trigger distress such as bereavement or loss of physical mobility. Distress is considered to be distinct to anxiety and/or depressio... Read More about How do older adults understand and manage distress? A qualitative study.

Role of the GP in the management of patients with self-harm behaviour: a systematic review (2020)
Journal Article
Troya, M., Mughal, F., Dikomitis, L., Chew-Graham, C. A., Corp, N., & Babatunde, O. O. (2020). Role of the GP in the management of patients with self-harm behaviour: a systematic review. British Journal of General Practice (BJGP), 70(694), E364-E373. https://doi.org/10.3399/bjgp20X708257

BACKGROUND: Self-harm is a serious risk factor for suicide, a major public health concern, and a significant burden on the NHS. Rates of self-harm presentation in primary care are rising and GPs interact with patients both before and after they have... Read More about Role of the GP in the management of patients with self-harm behaviour: a systematic review.

'We're the First Port of Call' - Perspectives of Ambulance Staff on Responding to Deaths by Suicide: A Qualitative Study (2020)
Journal Article
Chew-Graham. (2020). 'We're the First Port of Call' - Perspectives of Ambulance Staff on Responding to Deaths by Suicide: A Qualitative Study. Frontiers in Psychology, 722 -?. https://doi.org/10.3389/fpsyg.2020.00722

Introduction: Exposure to suicide is a known risk factor for suicide. Ambulance staff are exposed to work-related stressors including attending suicides, which may elevate their risk for mental health problems/suicide. Little is known about ambulance... Read More about 'We're the First Port of Call' - Perspectives of Ambulance Staff on Responding to Deaths by Suicide: A Qualitative Study.