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Rising burden of gout in the UK but continuing suboptimal management: a nationwide population study. (2015)
Journal Article
Mallen. (2015). Rising burden of gout in the UK but continuing suboptimal management: a nationwide population study. Annals of the Rheumatic Diseases, 661 - 667. https://doi.org/10.1136/annrheumdis-2013-204463

OBJECTIVES: To describe trends in the epidemiology of gout and patterns of urate-lowering treatment (ULT) in the UK general population from 1997 to 2012. METHODS: We used the Clinical Practice Research Datalink to estimate the prevalence and incidenc... Read More about Rising burden of gout in the UK but continuing suboptimal management: a nationwide population study..

Gout and risk of chronic kidney disease and nephrolithiasis: meta-analysis of observational studies (2015)
Journal Article
Mallen, Roddy, & Belcher. (2015). Gout and risk of chronic kidney disease and nephrolithiasis: meta-analysis of observational studies. Arthritis Research and Therapy, 17, Article 90. https://doi.org/10.1186/s13075-015-0610-9

ntroduction To determine the prevalence of chronic kidney disease and nephrolithiasis in people with gout, and the association between gout and prevalent or incident chronic kidney disease and nephrolithiasis. Methods Systematic review and meta-... Read More about Gout and risk of chronic kidney disease and nephrolithiasis: meta-analysis of observational studies.

Increased cardiovascular mortality associated with gout: a systematic review and meta-analysis (2015)
Journal Article
Roddy, Mallen, Belcher, Clarson, & Hider. (2015). Increased cardiovascular mortality associated with gout: a systematic review and meta-analysis. European Journal of Preventive Cardiology, 22(3), 335 -343. https://doi.org/10.1177/2047487313514895

BACKGROUND: Hyperuricaemia, the biochemical precursor to gout, has been shown to be an independent risk factor for mortality from cardiovascular disease (CVD), although studies examining the clinical phenomenon of gout and risk of CVD mortality repor... Read More about Increased cardiovascular mortality associated with gout: a systematic review and meta-analysis.

International variation in GP treatment strategies for subclinical hypothyroidism in older adults: a case-based survey. (2015)
Journal Article
Mallen. (2015). International variation in GP treatment strategies for subclinical hypothyroidism in older adults: a case-based survey. British Journal of General Practice (BJGP), e121 - e132. https://doi.org/10.3399/bjgp15X683569

BACKGROUND: There is limited evidence about the impact of treatment for subclinical hypothyroidism, especially among older people. AIM: To investigate the variation in GP treatment strategies for older patients with subclinical hypothyroidism dependi... Read More about International variation in GP treatment strategies for subclinical hypothyroidism in older adults: a case-based survey..

Improving the care of people with long-term conditions in primary care: protocol for the ENHANCE pilot trial (2015)
Journal Article
Healey, E. L., Jinks, C., Tan, V. A., Chew-Graham, C. A., Lawton, S. A., Nicholls, E., …Mallen, C. D. (2015). Improving the care of people with long-term conditions in primary care: protocol for the ENHANCE pilot trial. Journal of Comorbidity, 5(1), 135 -149. https://doi.org/10.15256/joc.2015.5.60

Background: Long-term conditions (LTCs) are important determinants of quality of life and healthcare expenditure worldwide. Whilst multimorbidity is increasingly the norm in primary care, clinical guidelines and the delivery of care remain focused o... Read More about Improving the care of people with long-term conditions in primary care: protocol for the ENHANCE pilot trial.

Increased risk of vascular disease associated with gout: a retrospective, matched cohort study in the UK clinical practice research datalink (2015)
Journal Article
Roddy, Mallen, Belcher, & Hider. (2015). Increased risk of vascular disease associated with gout: a retrospective, matched cohort study in the UK clinical practice research datalink. Annals of the Rheumatic Diseases, 642 - 647. https://doi.org/10.1136/annrheumdis-2014-206432

OBJECTIVES: To determine whether gout increases risk of incident coronary heart disease (CHD), cerebrovascular (CVD) and peripheral vascular disease (PVD) in a large cohort of primary care patients with gout, since there have been no such large studi... Read More about Increased risk of vascular disease associated with gout: a retrospective, matched cohort study in the UK clinical practice research datalink.

"I suddenly felt I'd aged": a qualitative study of patient experiences of polymyalgia rheumatica (PMR). (2015)
Journal Article
Twohig, H., Mitchell, C., Mallen, C., Adebajo, A., & Mathers, N. (2015). "I suddenly felt I'd aged": a qualitative study of patient experiences of polymyalgia rheumatica (PMR). Patient Education and Counseling, 98(5), 645 - 650. https://doi.org/10.1016/j.pec.2014.12.013

OBJECTIVES: To explore patient experiences of living with, and receiving treatment for, PMR. METHODS: Semi-structured qualitative interviews, with 22 patients with PMR recruited from general practices in South Yorkshire. Thematic analysis using a con... Read More about "I suddenly felt I'd aged": a qualitative study of patient experiences of polymyalgia rheumatica (PMR)..

An algorithm to identify rheumatoid arthritis in primary care: a Clinical Practice Research Datalink study. (2015)
Journal Article
Muller, S., Hider, S. L., Raza, K., Stack, R. J., Hayward, R. A., & Mallen, C. D. (2015). An algorithm to identify rheumatoid arthritis in primary care: a Clinical Practice Research Datalink study. BMJ Open, 5(12), Article e009309. https://doi.org/10.1136/bmjopen-2015-009309

OBJECTIVE: Rheumatoid arthritis (RA) is a multisystem, inflammatory disorder associated with increased levels of morbidity and mortality. While much research into the condition is conducted in the secondary care setting, routinely collected primary c... Read More about An algorithm to identify rheumatoid arthritis in primary care: a Clinical Practice Research Datalink study..

The Ariadne principles: how to handle multimorbidity in primary care consultations. (2014)
Journal Article
Mallen. (2014). The Ariadne principles: how to handle multimorbidity in primary care consultations. BMC Medicine, 223 - ?. https://doi.org/10.1186/s12916-014-0223-1

Multimorbidity is a health issue mostly dealt with in primary care practice. As a result of their generalist and patient-centered approach, long-lasting relationships with patients, and responsibility for continuity and coordination of care, family p... Read More about The Ariadne principles: how to handle multimorbidity in primary care consultations..

Repeated primary care consultations for non-specific physical symptoms in children in UK: a cohort study (2014)
Journal Article
Bucknall, M., Mallen, C. D., & Dunn, K. M. (2014). Repeated primary care consultations for non-specific physical symptoms in children in UK: a cohort study. BMC Family Practice, 195 - ?. https://doi.org/10.1186/s12875-014-0195-4

BackgroundNon-specific physical symptoms (NSPS), such as headache and abdominal pain, are common reasons for children to consult primary care. NSPS represent a significant burden not only on society, but also on health care services, through frequent... Read More about Repeated primary care consultations for non-specific physical symptoms in children in UK: a cohort study.

Comorbidities in patients with gout prior to and following diagnosis: case-control study. (2014)
Journal Article
Mallen. (2014). Comorbidities in patients with gout prior to and following diagnosis: case-control study. Annals of the Rheumatic Diseases, 210 - 217. https://doi.org/10.1136/annrheumdis-2014-206410

OBJECTIVES: To determine the burden of comorbidities in patients with gout at diagnosis and the risk of developing new comorbidities post diagnosis. METHODS: There were 39 111 patients with incident gout and 39 111 matched controls identified from th... Read More about Comorbidities in patients with gout prior to and following diagnosis: case-control study..

Fatigue as a precursor to polymyalgia rheumatica: an explorative retrospective cohort study. (2014)
Journal Article
Mallen, Hider, & Muller. (2014). Fatigue as a precursor to polymyalgia rheumatica: an explorative retrospective cohort study. Scandinavian Journal of Rheumatology, 219 - 223. https://doi.org/10.3109/03009742.2014.959047

OBJECTIVES: Polymyalgia rheumatica (PMR) is the commonest inflammatory disorder of older adults. Although not part of the recently published classification criteria, patients with PMR frequently complain of fatigue. We compared consultation for fatig... Read More about Fatigue as a precursor to polymyalgia rheumatica: an explorative retrospective cohort study..

Transcutaneous electrical nerve stimulation as adjunct to primary care management for tennis elbow: (2014)
Journal Article
Chesterton, L. S., Lewis, A. M., Sim, J., Mallen, C. D., Mason, E. E., Hay, E. M., & van der Windt, D. A. (2014). Transcutaneous electrical nerve stimulation as adjunct to primary care management for tennis elbow:. British Journal of Sports Medicine, 1458 - ?. https://doi.org/10.1136/bjsports-2013-f5160rep

Can transcutaneous electrical nerve stimulation (TENS), as a patient controlled adjunct to primary care management for tennis elbow, provide superior pain relief to primary care management alone.

Prevalence of female urinary incontinence and its impact on quality of life in a cluster population in the United Kingdom (UK): a community survey. (2014)
Journal Article
Mallen. (2014). Prevalence of female urinary incontinence and its impact on quality of life in a cluster population in the United Kingdom (UK): a community survey. Primary Health Care Research and Development, 377 - 382. https://doi.org/10.1017/S1463423614000371

AIM: To ascertain the prevalence of urinary incontinence and lower urinary tract symptoms, impact on quality of life and help-seeking behaviour. BACKGROUND: Urinary incontinence is common and will affect more individuals as the population ages. Estim... Read More about Prevalence of female urinary incontinence and its impact on quality of life in a cluster population in the United Kingdom (UK): a community survey..

The association between GP consultations for non-specific physical symptoms in children and parents: a case-control study (2014)
Journal Article
Bucknall, M., Shraim, M., Mallen, C. D., & Dunn, K. M. (2014). The association between GP consultations for non-specific physical symptoms in children and parents: a case-control study. PloS one, e108039 -?. https://doi.org/10.1371/journal.pone.0108039

BACKGROUND: Non-specific physical symptoms (NSPS) such as abdominal pain, headache and musculoskeletal pain are widespread in the community, and are common reasons for visiting a general practitioner (GP). Causes of NSPS are multifactorial, but may i... Read More about The association between GP consultations for non-specific physical symptoms in children and parents: a case-control study.