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All Outputs (418)

Burnout among primary health-care professionals in low- and middle-income countries: systematic review and meta-analysis (2022)
Journal Article
Helliwell, T., Wright, T., Mughal, F., Babatunde, O., Dikomitis, L., & Mallen, C. (2022). Burnout among primary health-care professionals in low- and middle-income countries: systematic review and meta-analysis. Bulletin of the World Health Organization, 385 - 401A. https://doi.org/10.2471/blt.22.288300

Objective To estimate the prevalence of burnout among primary health-care professionals in low- and middle-income countries and to identify factors associated with burnout. Methods We systematically searched nine databases up to February 2022 to... Read More about Burnout among primary health-care professionals in low- and middle-income countries: systematic review and meta-analysis.

Treatment and Outcomes of Acute Myocardial Infarction in Patients With Polymyalgia Rheumatica With and Without Giant Cell Arteritis. (2022)
Journal Article
Sokhal, B., Matetić, A., Bharadwaj, A., Helliwell, T., Abhishek, A., Mallen, C., …Mamas, M. (2022). Treatment and Outcomes of Acute Myocardial Infarction in Patients With Polymyalgia Rheumatica With and Without Giant Cell Arteritis. American Journal of Cardiology, 12-19. https://doi.org/10.1016/j.amjcard.2022.03.034

This study analyzed the characteristics, management, and outcomes of patients with polymyalgia rheumatica (PMR) hospitalized with acute myocardial infarction (AMI), including sensitivity analysis for presence of giant cell arteritis (GCA). Using the... Read More about Treatment and Outcomes of Acute Myocardial Infarction in Patients With Polymyalgia Rheumatica With and Without Giant Cell Arteritis..

P181 Musculoskeletal pain and prognosis of acute coronary syndrome and cerebrovascular accident: a linked electronic health record cohort study (2022)
Journal Article
Mason, K. J., Jordan, K. P., Achana, F. A., Bailey, J., Chen, Y., Frisher, M., …Edwards, J. J. (2022). P181 Musculoskeletal pain and prognosis of acute coronary syndrome and cerebrovascular accident: a linked electronic health record cohort study. Rheumatology, 61(S1), https://doi.org/10.1093/rheumatology/keac133.180

Abstract Background/Aims There is some evidence of an increased risk of cardiovascular disease in patients with painful musculoskeletal conditions, but it is unclear if musculoskeletal pain also worsens its prognosis. The aim was to determine whethe... Read More about P181 Musculoskeletal pain and prognosis of acute coronary syndrome and cerebrovascular accident: a linked electronic health record cohort study.

P183 Establishing the epidemiology of rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis in England using primary care electronic health record data (2022)
Journal Article
Scott, I. C., Whittle, R., Bailey, J., Twohig, H., Hider, S., Mallen, C., …Jordan, K. (2022). P183 Establishing the epidemiology of rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis in England using primary care electronic health record data. Rheumatology, 61(S1), https://doi.org/10.1093/rheumatology/keac133.182

Abstract Background/Aims The substantial personal and socioeconomic costs associated with rheumatoid arthritis (RA), psoriatic arthritis (PsA), and axial spondyloarthritis (SpA) make understanding their epidemiology crucial. The Clinical Practice Re... Read More about P183 Establishing the epidemiology of rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis in England using primary care electronic health record data.

Comorbidities in osteoarthritis (ComOA): a combined cross-sectional, case-control and cohort study using large electronic health records in four European countries. (2022)
Journal Article
Zhang, W., Runhaar, J., Dell'Isola, A., Turkiewicz, A., Swain, S., Kamps, A., …Bierma-Zeinstra, S. (2022). Comorbidities in osteoarthritis (ComOA): a combined cross-sectional, case-control and cohort study using large electronic health records in four European countries. BMJ Open, e052816 - ?. https://doi.org/10.1136/bmjopen-2021-052816

INTRODUCTION: Osteoarthritis (OA) is one of the leading chronic conditions in the older population. People with OA are more likely to have one or more other chronic conditions than those without. However, the temporal associations, clusters of the co... Read More about Comorbidities in osteoarthritis (ComOA): a combined cross-sectional, case-control and cohort study using large electronic health records in four European countries..

Clinical effectiveness of one ultrasound guided intra-articular corticosteroid and local anaesthetic injection in addition to advice and education for hip osteoarthritis (HIT trial): single blind, parallel group, three arm, randomised controlled trial (2022)
Journal Article
Paskins, Z., Bromley, K., Lewis, M., Hughes, G., Hughes, E., Hennings, S., …Mallen, C. D. (2022). Clinical effectiveness of one ultrasound guided intra-articular corticosteroid and local anaesthetic injection in addition to advice and education for hip osteoarthritis (HIT trial): single blind, parallel group, three arm, randomised controlled trial. BMJ, 377, Article ARTN e068446. https://doi.org/10.1136/bmj-2021-068446

Objectives: to compare the clinical effectiveness of best current treatment (BCT) plus single ultrasound-guided intra-articular hip injection (USGI) of 40mg triamcinolone acetonide and 4ml 1% lidocaine hydrochloride [BCT+US-Triamcinolone-Lidocaine] w... Read More about Clinical effectiveness of one ultrasound guided intra-articular corticosteroid and local anaesthetic injection in addition to advice and education for hip osteoarthritis (HIT trial): single blind, parallel group, three arm, randomised controlled trial.

A Review of the Wide Range of Indications and Uses of Implantable Loop Recorders: A Review of the Literature (2022)
Journal Article
Darlington, D., Mayer, J., Panchal, G., Zachariah, D., Phan, T., Mallen, C., …Walker, V. (2022). A Review of the Wide Range of Indications and Uses of Implantable Loop Recorders: A Review of the Literature. Hearts, https://doi.org/10.3390/hearts3020007

Implantable loop recorders (ILR) are devices that are implanted subcutaneously on the chest, which enables the continuous monitoring of arrhythmias for up to three years. These devices have an important role in helping to make a diagnosis and support... Read More about A Review of the Wide Range of Indications and Uses of Implantable Loop Recorders: A Review of the Literature.

Clinician views on optimism and empathy in primary care consultations: a qualitative interview study (2022)
Journal Article
Hughes, S., Vennik, J., Smith, K., Bostock, J., Howick, J., Mallen, C., …Everitt, H. (2022). Clinician views on optimism and empathy in primary care consultations: a qualitative interview study. British Journal of General Practice Open (BJGP Open), 6(3), Article 0221. https://doi.org/10.3399/BJGPO.2021.0221

Background: Practitioner expressions of optimism and empathy may improve treatment engagement, adherence, and patient satisfaction but are not delivered consistently amid the challenges of everyday clinical practice. Aim: To explore primary care p... Read More about Clinician views on optimism and empathy in primary care consultations: a qualitative interview study.

The impact of COVID-19 on the patient, clinician, healthcare services and society: A patient pathway review. (2022)
Journal Article
Kwok, C. S., Muntean, E., & Mallen, C. D. (2022). The impact of COVID-19 on the patient, clinician, healthcare services and society: A patient pathway review. Journal of Medical Virology, 94(8), 3634-3641. https://doi.org/10.1002/jmv.27758

The spread of COVID-19 infection has changed the world. Population-based studies of COVID-19 are limited because it is unknown why events happen or why certain outcomes occur. An alternative approach called the patient pathway review evaluates what h... Read More about The impact of COVID-19 on the patient, clinician, healthcare services and society: A patient pathway review..

Identification of undiagnosed atrial fibrillation using a machine learning risk prediction algorithm and diagnostic testing (PULsE-AI) in primary care: a multi-centre randomised controlled trial in England (2022)
Journal Article
Hill, N. R., Groves, L., Dickerson, C., Ochs, A., Pang, D., Lawton, S., …Cohen, A. T. (2022). Identification of undiagnosed atrial fibrillation using a machine learning risk prediction algorithm and diagnostic testing (PULsE-AI) in primary care: a multi-centre randomised controlled trial in England. European Heart Journal, S111 - S111. https://doi.org/10.1093/ehjdh/ztac009

The clinical effectiveness of a physiotherapy delivered physical and psychological group intervention for older adults with neurogenic claudication: the BOOST randomised controlled trial. (2022)
Journal Article
Mallen. (2022). The clinical effectiveness of a physiotherapy delivered physical and psychological group intervention for older adults with neurogenic claudication: the BOOST randomised controlled trial. The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences, https://doi.org/10.1093/gerona/glac063

BACKGROUND: Neurogenic claudication (NC) is a debilitating spinal condition affecting older adults' mobility and quality of life. METHODS: A randomised controlled trial of 438 participants evaluated the effectiveness of a physical and psychological g... Read More about The clinical effectiveness of a physiotherapy delivered physical and psychological group intervention for older adults with neurogenic claudication: the BOOST randomised controlled trial..

Diagnostic delay in axial spondyloarthritis: a systematic review (2022)
Journal Article
Hay, C., Packham, J., Ryan, S., Mallen, C., Chatzixenitidis, A., & Prior, J. (2022). Diagnostic delay in axial spondyloarthritis: a systematic review. Clinical Rheumatology, 41(1939–1950), https://doi.org/10.1007/s10067-022-06100-7

Identification of axial spondyloarthritis (axSpA) remains challenging, frequently resulting in a diagnostic delay for patients. Current benchmarks of delay are usually reported as mean data, which are typically skewed and therefore may be overestimat... Read More about Diagnostic delay in axial spondyloarthritis: a systematic review.

Clustering of comorbidities and associated outcomes in people with osteoarthritis - a UK Clinical Practice Research Datalink study. (2022)
Journal Article
Englund, M., Prieto-Alhambra, D., Zhang, W., Doherty, M., Swain, S., Coupland, C., …Bierma-Zeinstra, S. (2022). Clustering of comorbidities and associated outcomes in people with osteoarthritis - a UK Clinical Practice Research Datalink study. Osteoarthritis and Cartilage, https://doi.org/10.1016/j.joca.2021.12.013

OBJECTIVE: To examine the clusters of chronic conditions present in people with osteoarthritis and the associated risk factors and health outcomes. METHODS: Clinical Practice Research Datalink (CPRD) GOLD was used to identify people diagnosed with in... Read More about Clustering of comorbidities and associated outcomes in people with osteoarthritis - a UK Clinical Practice Research Datalink study..

Patient pathways in cardiology: Should pharmaceutical and medical device companies care? (2022)
Journal Article
Kwok, C. S., Muntean, E., Muntean, E., Foster, W., & Mallen, C. D. (2022). Patient pathways in cardiology: Should pharmaceutical and medical device companies care?. Critical Pathways in Cardiology: A Journal of Evidence-Based Medicine, 21(1), 57-60. https://doi.org/10.1097/HPC.0000000000000278

A shared goal of patients, providers and the companies that produce new therapies is to have these therapies used according to guidelines. Health services specialize in patient care and may lack the capabilities to take a product from conception thro... Read More about Patient pathways in cardiology: Should pharmaceutical and medical device companies care?.

Prevalence of Occupational Stress among Secondary School Teachers in Public Schools in the District of Colombo, Sri Lanka (2022)
Journal Article
Wickramasinghe, E., Seneviratne, R. D. A., Gunawardana, N., Sumathipala, A., & Mallen, C. (2022). Prevalence of Occupational Stress among Secondary School Teachers in Public Schools in the District of Colombo, Sri Lanka. https://doi.org/10.22158/rhs.v7n3p12

Teacher occupational stress is increasing globally. We aimed to determine the prevalence of occupational stress among secondary teachers, to advocate policies for prevention of occupational stress among teachers in Sri Lanka. A cross-sectional study... Read More about Prevalence of Occupational Stress among Secondary School Teachers in Public Schools in the District of Colombo, Sri Lanka.

The impact of COVID-19 on primary care: insights from the National Health Service (NHS) and future recommendations (2021)
Journal Article
Mallen, C., Khunti, K., & Mughal, F. (2021). The impact of COVID-19 on primary care: insights from the National Health Service (NHS) and future recommendations. Journal of Family Medicine and Primary Care, 4345-4349. https://doi.org/10.4103/jfmpc.jfmpc_756_21

COVID-19 has changed health systems and services. In this commentary, we outline the impact COVID-19 has had on the delivery of primary health care, and on primary care teams, and describe the NHS response. We highlight the challenges of managing lon... Read More about The impact of COVID-19 on primary care: insights from the National Health Service (NHS) and future recommendations.

Predictors of interest in predictive testing for rheumatoid arthritis among first degree relatives of rheumatoid arthritis patients (2021)
Journal Article
Mallen, Wells, I., T Zemedikun, D., Simons, G., J Stack, R., D Mallen, C., …Falahee, M. (2022). Predictors of interest in predictive testing for rheumatoid arthritis among first degree relatives of rheumatoid arthritis patients. Rheumatology, 61(8), https://doi.org/10.1093/rheumatology/keab890

OBJECTIVES: There is increasing interest in prediction and prevention of rheumatoid arthritis (RA). It is important to understand the views of those at risk to inform the development of effective approaches. First-degree relatives (FDRs) of RA patien... Read More about Predictors of interest in predictive testing for rheumatoid arthritis among first degree relatives of rheumatoid arthritis patients.

Fragility fractures and prescriptions of medications for osteoporosis in patients with polymyalgia rheumatica: results from the PMR Cohort Study (2021)
Journal Article
Paskins, Z., Sokhal, B. S., Hider, S. L., Mallen, C. D., & Muller, S. (2021). Fragility fractures and prescriptions of medications for osteoporosis in patients with polymyalgia rheumatica: results from the PMR Cohort Study. Rheumatology Advances in Practice, Article rkab094. https://doi.org/10.1093/rap/rkab094

OBJECTIVES: PMR is a common indication for long-term glucocorticoid treatment, leading to an increased risk of osteoporosis and fragility fractures. Guidelines recommend calcium and vitamin D for all patients, in addition to anti-resorptive agents fo... Read More about Fragility fractures and prescriptions of medications for osteoporosis in patients with polymyalgia rheumatica: results from the PMR Cohort Study.

Analgesic prescribing in patients with inflammatory arthritis in England: an observational study using electronic healthcare record data (2021)
Journal Article
Scott, I. C., Bailey, J., White, C. R., Mallen, C., & Muller, S. (2022). Analgesic prescribing in patients with inflammatory arthritis in England: an observational study using electronic healthcare record data. Rheumatology, 61(8), 3201–3211. https://doi.org/10.1093/rheumatology/keab870

OBJECTIVES: International data suggest inflammatory arthritis (IA) pain management frequently involves opioid prescribing, despite little evidence of efficacy, and potential harms. We evaluated analgesia prescribing in English National Health Service... Read More about Analgesic prescribing in patients with inflammatory arthritis in England: an observational study using electronic healthcare record data.