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All Outputs (43)

Gender-specific risk factors for gout: a systematic review of cohort studies (2019)
Journal Article
Evans, P. L., Prior, J. A., Belcher, J., Hay, C. A., Mallen, C. D., & Roddy, E. (2019). Gender-specific risk factors for gout: a systematic review of cohort studies. Advances in Rheumatology, 59, Article 24. https://doi.org/10.1186/s42358-019-0067-7

BACKGROUND: Though gout is more prevalent in men than women, it remains unclear whether gender influences risk factors for incident gout. We aimed to systematically review all cohort studies examining risk factors for the development of gout by gend... Read More about Gender-specific risk factors for gout: a systematic review of cohort studies.

Incidence of infections associated with oral glucocorticoid dose in people diagnosed with polymyalgia rheumatica or giant cell arteritis: a cohort study in England (2019)
Journal Article
Mallen. (2019). Incidence of infections associated with oral glucocorticoid dose in people diagnosed with polymyalgia rheumatica or giant cell arteritis: a cohort study in England. Canadian Medical Association Journal, E680 - E688. https://doi.org/10.1503/cmaj.190178

BACKGROUND: Most patients with polymyalgia rheumatica or giant cell arteritis are treated with glucocorticoid therapy in primary care. We estimated dose-response risks of infection for this population in England. METHODS: We conducted a retrospect... Read More about Incidence of infections associated with oral glucocorticoid dose in people diagnosed with polymyalgia rheumatica or giant cell arteritis: a cohort study in England.

2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout. (2019)
Journal Article
Richette, P., Doherty, M., Pascual, E., Barskova, V., Becce, F., Castaneda, J., …Bardin, T. (2019). 2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout. Annals of the Rheumatic Diseases, 79(1), 31 - 38. https://doi.org/10.1136/annrheumdis-2019-215315

Although gout is the most common inflammatory arthritis, it is still frequently misdiagnosed. New data on imaging and clinical diagnosis have become available since the first EULAR recommendations for the diagnosis of gout in 2006. This prompted a sy... Read More about 2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout..

Venous thromboembolism in patients with gout and the impact of hospital admission, disease duration and urate-lowering therapy. (2019)
Journal Article
Mallen, C., Roddy, E., Clarson, L., & Muller, S. (2019). Venous thromboembolism in patients with gout and the impact of hospital admission, disease duration and urate-lowering therapy. Canadian Medical Association Journal, 191(22), E597 - E603. https://doi.org/10.1503/cmaj.180717

BACKGROUND: Systemic inflammatory diseases have been associated with increased risk of venous thromboembolism. We aimed to quantify the risk of venous thromboembolism in patients with gout, the most common inflammatory arthritis, and to assess how di... Read More about Venous thromboembolism in patients with gout and the impact of hospital admission, disease duration and urate-lowering therapy..

Assessing the Severity of Type 2 Diabetes Using Clinical Data Based Measures: a Systematic Review (2019)
Journal Article
Mallen, Chew-Graham, & Mamas. (2019). Assessing the Severity of Type 2 Diabetes Using Clinical Data Based Measures: a Systematic Review. Diabetic Medicine, 688-701. https://doi.org/10.1111/dme.13905

Aims To identify and critically appraise measures that use clinical data to grade the severity of Type 2 diabetes. Methods We searched MEDLINE, Embase and PubMed between inception and June 2018. Studies reporting on clinical data-based diabetes-... Read More about Assessing the Severity of Type 2 Diabetes Using Clinical Data Based Measures: a Systematic Review.

Matching treatment options for risk sub-groups in musculoskeletal pain: a consensus groups study (2019)
Journal Article
Protheroe, J., Saunders, B., Bartlam, B., Dunn, K., Cooper, V., Campbell, P., …Foster, N. (2019). Matching treatment options for risk sub-groups in musculoskeletal pain: a consensus groups study. BMC Musculoskeletal Disorders, https://doi.org/10.1186/s12891-019-2587-z

Background Musculoskeletal (MSK) pain represents a considerable worldwide healthcare burden. This study aimed to gain consensus from practitioners who work with MSK pain patients, on the most appropriate primary care treatment options for subgroups... Read More about Matching treatment options for risk sub-groups in musculoskeletal pain: a consensus groups study.

The association of pain and stiffness with fatigue in incident polymyalgia rheumatica: baseline results from the polymyalgia rheumatica cohort study (2019)
Report
Prior, J., Muller, S., Helliwell, T., Hider, S., Barraclough, K., Dasgupta, B., & Mallen, C. (2019). The association of pain and stiffness with fatigue in incident polymyalgia rheumatica: baseline results from the polymyalgia rheumatica cohort study

We aimed to examine the association between pain, stiffness and fatigue in newly diagnosed polymyalgia rheumatica (PMR) patients using baseline data from a prospective cohort study. Fatigue is a known, but often ignored symptom of PMR. Newly diagnose... Read More about The association of pain and stiffness with fatigue in incident polymyalgia rheumatica: baseline results from the polymyalgia rheumatica cohort study.

Symptoms associated with inflammatory arthritis are common in the primary care population: results from the Joint Symptoms Survey (2019)
Journal Article
Hider, S. L., Muller, S., Helliwell, T., Prior, J. A., Scott, I., Lawton, S. A., …Mallen, C. D. (2019). Symptoms associated with inflammatory arthritis are common in the primary care population: results from the Joint Symptoms Survey. Rheumatology, 58(11), 2009-2014. https://doi.org/10.1093/rheumatology/kez184

Objectives: To describe the prevalence of self-reported inflammatory joint symptoms, such as joint pain, stiffness and swelling in UK primary care patients consulting for both musculoskeletal (MSK) and non-musculoskeletal (non-MSK) complaints. Met... Read More about Symptoms associated with inflammatory arthritis are common in the primary care population: results from the Joint Symptoms Survey.

Temporal relationships between systemic lupus erythematosus and comorbidities (2019)
Journal Article
Mallen. (2019). Temporal relationships between systemic lupus erythematosus and comorbidities. Rheumatology, 840-848. https://doi.org/10.1093/rheumatology/key335

Objective To examine the burden of comorbidities prior to and after the diagnosis of SLE and its impact on mortality. Methods We identified 1605 incident cases of SLE and 6284 matched controls from the UK primary care. The risks of comorbidities... Read More about Temporal relationships between systemic lupus erythematosus and comorbidities.

Effectiveness of inactivated influenza vaccine in autoimmune rheumatic diseases treated with disease modifying anti-rheumatic drugs. (2019)
Journal Article
Mallen. (2019). Effectiveness of inactivated influenza vaccine in autoimmune rheumatic diseases treated with disease modifying anti-rheumatic drugs. Annals of the Rheumatic Diseases, https://doi.org/10.1136/annrheumdis-2019-215086

Objectives To examine the association between inactivated influenza vaccine (IIV) administration and primary care consultation for joint pain, rheumatoid arthritis (RA) flare, corticosteroid prescription, vasculitis and unexplained fever in people w... Read More about Effectiveness of inactivated influenza vaccine in autoimmune rheumatic diseases treated with disease modifying anti-rheumatic drugs..

E042 Predicting duration of glucocorticoid therapy in an inception cohort of patients with polymyalgia rheumatica (2019)
Journal Article
Morton, C., Muller, S., Hider, S., Belcher, J., Mallen, C. D., & Helliwell, T. (2019). E042 Predicting duration of glucocorticoid therapy in an inception cohort of patients with polymyalgia rheumatica. Rheumatology, 58(Supplement_3), https://doi.org/10.1093/rheumatology/kez110.041

Background: Extended duration of glucocorticoid (GC) therapy can be considered a poor outcome in people with polymyalgia rheumatica (PMR). Being able to predict the likelihood of extended GC therapy at diagnosis would enable earlier specialist referr... Read More about E042 Predicting duration of glucocorticoid therapy in an inception cohort of patients with polymyalgia rheumatica.

216 Characteristics of patients with prevalent giant cell arteritis in UK primary care (2019)
Journal Article
Twomlow, E. L., Prior, J. A., Mackie, S. L., Helliwell, T., Hider, S. L., Belcher, J., …Mallen, C. D. (2019). 216 Characteristics of patients with prevalent giant cell arteritis in UK primary care. Rheumatology, 58(Supplement_3), https://doi.org/10.1093/rheumatology/kez107.032

Background: Giant cell arteritis (GCA) is a rare, but serious condition affecting older people. Prompt diagnosis remains challenging due to non-specific presentations. Furthermore, there are marked variations in GP referral and management approaches.... Read More about 216 Characteristics of patients with prevalent giant cell arteritis in UK primary care.

202 Gout attack trajectories in a 3-year cohort study in primary care (2019)
Journal Article
Watson, L., Belcher, J., Mallen, C. D., & Roddy, E. (2019). 202 Gout attack trajectories in a 3-year cohort study in primary care. Rheumatology, 58(Supplement_3), https://doi.org/10.1093/rheumatology/kez107.018

Background: Gout affects 2.5% of adults in the UK but is often poorly managed. Whilst the hallmark of gout is recurrent sudden-onset attacks of acute joint pain and swelling, little is known about the pattern (trajectory) of attacks over time. We aim... Read More about 202 Gout attack trajectories in a 3-year cohort study in primary care.

A systematic review of measures using clinical data for assessing the severity of Type 2 diabetes (2019)
Presentation / Conference
Zghebi, S., Panagioti, M., Rutter, M., Ashcroft, D., van Marwijk, H., Salisbury, C., …Kontopantelis, E. (2019, March). A systematic review of measures using clinical data for assessing the severity of Type 2 diabetes. Poster presented at Diabetes UK Professional Conference 2019, ACC Liverpool, Liverpool, UK

Background/Aims: The assessment of disease severity in people with diabetes enables identification of patients in need for intensive and targeted therapies, and could help optimise the allocation of healthcare resources. We aimed to identify and appr... Read More about A systematic review of measures using clinical data for assessing the severity of Type 2 diabetes.

Delays between the onset of symptoms and first rheumatology consultation in patients with rheumatoid arthritis in the UK: an observational study. (2019)
Journal Article
Jayne Stack, R., Nightingale, P., Jinks, C., Shaw, K., Herron-Marx, S., Horne, R., …Raza, K. (2019). Delays between the onset of symptoms and first rheumatology consultation in patients with rheumatoid arthritis in the UK: an observational study. BMJ Open, 9(3), Article e024361. https://doi.org/10.1136/bmjopen-2018-024361

OBJECTIVE: To investigate delays from symptom onset to rheumatology assessment for patients with a new onset of rheumatoid arthritis (RA) or unclassified arthritis. METHODS: Newly presenting adults with either RA or unclassified arthritis were recrui... Read More about Delays between the onset of symptoms and first rheumatology consultation in patients with rheumatoid arthritis in the UK: an observational study..

Multisite pain and self-reported falls in older people: systematic review and meta-analysis. (2019)
Journal Article
Welsh, V., Clarson, L. E., Mallen, C., & McBeth, J. (2019). Multisite pain and self-reported falls in older people: systematic review and meta-analysis. Arthritis Research and Therapy, 67 - ?. https://doi.org/10.1186/s13075-019-1847-5

BACKGROUND: Multisite pain and falls are common in older people, and isolated studies have identified multisite pain as a potential falls risk factor. This study aims to synthesise published literature to further explore the relationship between mu... Read More about Multisite pain and self-reported falls in older people: systematic review and meta-analysis..

Musculoskeletal symptoms and non-prescribed treatments are common in an urban African population of people living with HIV. (2019)
Journal Article
Mallen. (2019). Musculoskeletal symptoms and non-prescribed treatments are common in an urban African population of people living with HIV. Rheumatology International, 285-291. https://doi.org/10.1007/s00296-018-4188-9

There are no data from West Africa reporting musculoskeletal (MSK) disease in people living with HIV (PLWH). Our primary outcome was to measure the prevalence of MSK symptoms in PLWH in urban West Africa. Our secondary outcomes were to describe the d... Read More about Musculoskeletal symptoms and non-prescribed treatments are common in an urban African population of people living with HIV..