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All Outputs (39)

One-year trajectories of depression and anxiety symptoms in older patients presenting in general practice with musculoskeletal pain: A latent class growth analysis. (2015)
Journal Article
Rzewuska, M., Mallen, C. D., Strauss, V. Y., Belcher, J., & Peat, G. (2015). One-year trajectories of depression and anxiety symptoms in older patients presenting in general practice with musculoskeletal pain: A latent class growth analysis. Journal of Psychosomatic Research, 79(3), 195 - 201. https://doi.org/10.1016/j.jpsychores.2015.05.016

OBJECTIVE: Distinguishing transient from persistent anxiety and depression symptoms in older people presenting to general practice with musculoskeletal pain is potentially important for effective management. This study sought to identify distinct pos... Read More about One-year trajectories of depression and anxiety symptoms in older patients presenting in general practice with musculoskeletal pain: A latent class growth analysis..

306. How Do General Practitioners Manage Suspected Giant Cell Arteritis (2015)
Journal Article
Helliwell, T., Muller, S., Hider, S. L., Richardson, J., & Mallen, C. (2015). 306. How Do General Practitioners Manage Suspected Giant Cell Arteritis. Rheumatology, 54(S1), https://doi.org/10.1093/rheumatology/kev090.071

Background: Background: GCA is the commonest large vessel vasculitis yet a full time UK general practitioner (GP) can expect to see just one case, at most every 1–2 years. Untreated GCA can lead to permanent visual loss, thus it is essential GPs reco... Read More about 306. How Do General Practitioners Manage Suspected Giant Cell Arteritis.

046. Integrating Care for Joint Pain and Anxiety and Depression into Reviews for Long-Term Conditions: The Enhance Study (2015)
Journal Article
Jinks, C., Morden, A., Chew-Graham, C., Porcheret, M., Finney, A., Dziedzic, K., …Mallen, C. (2015). 046. Integrating Care for Joint Pain and Anxiety and Depression into Reviews for Long-Term Conditions: The Enhance Study. Rheumatology, 54(S1), https://doi.org/10.1093/rheumatology/kev088.046

Joint pain and mental health problems are common and often co-exist with other long-term conditions (LTCs), but are under-detected and sub-optimally managed in primary care. The aim of the ENHANCE study is to develop and test the feasibility and acc... Read More about 046. Integrating Care for Joint Pain and Anxiety and Depression into Reviews for Long-Term Conditions: The Enhance Study.

O31. Gout and Risk of Subsequent Vascular Event: A Discrete-Time Event History Analysis in the Clinical Practice Research Datalink (2015)
Journal Article
Clarson, L. E., Hider, S. L., Belcher, J., Roddy, E., Heneghan, C., & Mallen, C. D. (2015). O31. Gout and Risk of Subsequent Vascular Event: A Discrete-Time Event History Analysis in the Clinical Practice Research Datalink. Rheumatology, 54(S1), https://doi.org/10.1093/rheumatology/kev084.001

Background: Current evidence suggests that gout is an independent risk factor for excess cardiovascular morbidity and mortality; yet, suboptimal care for patients with gout in primary care persists. We aimed to identify risk factors specific to these... Read More about O31. Gout and Risk of Subsequent Vascular Event: A Discrete-Time Event History Analysis in the Clinical Practice Research Datalink.

Rising burden of gout in the UK but continuing suboptimal management: a nationwide population study. (2015)
Journal Article
Mallen. (2015). Rising burden of gout in the UK but continuing suboptimal management: a nationwide population study. Annals of the Rheumatic Diseases, 661 - 667. https://doi.org/10.1136/annrheumdis-2013-204463

OBJECTIVES: To describe trends in the epidemiology of gout and patterns of urate-lowering treatment (ULT) in the UK general population from 1997 to 2012. METHODS: We used the Clinical Practice Research Datalink to estimate the prevalence and incidenc... Read More about Rising burden of gout in the UK but continuing suboptimal management: a nationwide population study..

Gout and risk of chronic kidney disease and nephrolithiasis: meta-analysis of observational studies (2015)
Journal Article
Mallen, Roddy, & Belcher. (2015). Gout and risk of chronic kidney disease and nephrolithiasis: meta-analysis of observational studies. Arthritis Research and Therapy, 17, Article 90. https://doi.org/10.1186/s13075-015-0610-9

ntroduction To determine the prevalence of chronic kidney disease and nephrolithiasis in people with gout, and the association between gout and prevalent or incident chronic kidney disease and nephrolithiasis. Methods Systematic review and meta-... Read More about Gout and risk of chronic kidney disease and nephrolithiasis: meta-analysis of observational studies.

Prevalence of genital prolapse symptoms in primary care: a cross-sectional survey. (2015)
Journal Article
Cooper, J., Annappa, M., Dracocardos, D., Cooper, W., Muller, S., & Mallen, C. (2015). Prevalence of genital prolapse symptoms in primary care: a cross-sectional survey. International Urogynecology Journal, 505 - 510. https://doi.org/10.1007/s00192-014-2556-x

INTRODUCTION AND HYPOTHESIS: The aim of our study was to determine the prevalence of pelvic organ prolapse (POP) symptoms in a community-dwelling population in the United Kingdom. METHODS: All women over the age of 18 from a community practice were s... Read More about Prevalence of genital prolapse symptoms in primary care: a cross-sectional survey..

A qualitative investigation of the barriers to help-seeking among members of the public presented with symptoms of new-onset rheumatoid arthritis. (2015)
Journal Article
Mallen. (2015). A qualitative investigation of the barriers to help-seeking among members of the public presented with symptoms of new-onset rheumatoid arthritis. Journal of Rheumatology, 585 - 592. https://doi.org/10.3899/jrheum.140913

OBJECTIVE: Treating patients with rheumatoid arthritis (RA) within 3 months of symptom onset leads to significantly improved clinical outcomes. However, many people with RA symptoms wait a long time before seeking medical attention. To develop effect... Read More about A qualitative investigation of the barriers to help-seeking among members of the public presented with symptoms of new-onset rheumatoid arthritis..

Increased cardiovascular mortality associated with gout: a systematic review and meta-analysis (2015)
Journal Article
Roddy, Mallen, Belcher, Clarson, & Hider. (2015). Increased cardiovascular mortality associated with gout: a systematic review and meta-analysis. European Journal of Preventive Cardiology, 22(3), 335 -343. https://doi.org/10.1177/2047487313514895

BACKGROUND: Hyperuricaemia, the biochemical precursor to gout, has been shown to be an independent risk factor for mortality from cardiovascular disease (CVD), although studies examining the clinical phenomenon of gout and risk of CVD mortality repor... Read More about Increased cardiovascular mortality associated with gout: a systematic review and meta-analysis.

International variation in GP treatment strategies for subclinical hypothyroidism in older adults: a case-based survey. (2015)
Journal Article
Mallen. (2015). International variation in GP treatment strategies for subclinical hypothyroidism in older adults: a case-based survey. British Journal of General Practice (BJGP), e121 - e132. https://doi.org/10.3399/bjgp15X683569

BACKGROUND: There is limited evidence about the impact of treatment for subclinical hypothyroidism, especially among older people. AIM: To investigate the variation in GP treatment strategies for older patients with subclinical hypothyroidism dependi... Read More about International variation in GP treatment strategies for subclinical hypothyroidism in older adults: a case-based survey..

Improving the care of people with long-term conditions in primary care: protocol for the ENHANCE pilot trial (2015)
Journal Article
Healey, E. L., Jinks, C., Tan, V. A., Chew-Graham, C. A., Lawton, S. A., Nicholls, E., …Mallen, C. D. (2015). Improving the care of people with long-term conditions in primary care: protocol for the ENHANCE pilot trial. Journal of Comorbidity, 5(1), 135 -149. https://doi.org/10.15256/joc.2015.5.60

Background: Long-term conditions (LTCs) are important determinants of quality of life and healthcare expenditure worldwide. Whilst multimorbidity is increasingly the norm in primary care, clinical guidelines and the delivery of care remain focused o... Read More about Improving the care of people with long-term conditions in primary care: protocol for the ENHANCE pilot trial.

Increased risk of vascular disease associated with gout: a retrospective, matched cohort study in the UK clinical practice research datalink (2015)
Journal Article
Roddy, Mallen, Belcher, & Hider. (2015). Increased risk of vascular disease associated with gout: a retrospective, matched cohort study in the UK clinical practice research datalink. Annals of the Rheumatic Diseases, 642 - 647. https://doi.org/10.1136/annrheumdis-2014-206432

OBJECTIVES: To determine whether gout increases risk of incident coronary heart disease (CHD), cerebrovascular (CVD) and peripheral vascular disease (PVD) in a large cohort of primary care patients with gout, since there have been no such large studi... Read More about Increased risk of vascular disease associated with gout: a retrospective, matched cohort study in the UK clinical practice research datalink.

"I suddenly felt I'd aged": a qualitative study of patient experiences of polymyalgia rheumatica (PMR). (2015)
Journal Article
Twohig, H., Mitchell, C., Mallen, C., Adebajo, A., & Mathers, N. (2015). "I suddenly felt I'd aged": a qualitative study of patient experiences of polymyalgia rheumatica (PMR). Patient Education and Counseling, 98(5), 645 - 650. https://doi.org/10.1016/j.pec.2014.12.013

OBJECTIVES: To explore patient experiences of living with, and receiving treatment for, PMR. METHODS: Semi-structured qualitative interviews, with 22 patients with PMR recruited from general practices in South Yorkshire. Thematic analysis using a con... Read More about "I suddenly felt I'd aged": a qualitative study of patient experiences of polymyalgia rheumatica (PMR)..

An algorithm to identify rheumatoid arthritis in primary care: a Clinical Practice Research Datalink study. (2015)
Journal Article
Muller, S., Hider, S. L., Raza, K., Stack, R. J., Hayward, R. A., & Mallen, C. D. (2015). An algorithm to identify rheumatoid arthritis in primary care: a Clinical Practice Research Datalink study. BMJ Open, 5(12), Article e009309. https://doi.org/10.1136/bmjopen-2015-009309

OBJECTIVE: Rheumatoid arthritis (RA) is a multisystem, inflammatory disorder associated with increased levels of morbidity and mortality. While much research into the condition is conducted in the secondary care setting, routinely collected primary c... Read More about An algorithm to identify rheumatoid arthritis in primary care: a Clinical Practice Research Datalink study..