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Development and external validation of risk scores for cardiovascular hospitalisation and rehospitalisation in diabetes patients (2018)
Journal Article
Yu. (2018). Development and external validation of risk scores for cardiovascular hospitalisation and rehospitalisation in diabetes patients. The Journal of Clinical Endocrinology & Metabolism, 1122-1129. https://doi.org/10.1210/jc.2017-02293

Context: Cardiovascular disease (CVD) is a common and costly reason for hospitalization and rehospitalization among patients with type 2 diabetes. Objective: This study aimed to develop and externally validate two risk- prediction models for cardi... Read More about Development and external validation of risk scores for cardiovascular hospitalisation and rehospitalisation in diabetes patients.

Dialysate Creatinine Response Patterns During Peritoneal Equilibration Test and the Association Between Cardiovascular Mortality: Findings from a Prospective Cohort Study. (2018)
Journal Article
Yu. (2018). Dialysate Creatinine Response Patterns During Peritoneal Equilibration Test and the Association Between Cardiovascular Mortality: Findings from a Prospective Cohort Study. Kidney and Blood Pressure Research, https://doi.org/10.1159/000487498

Background/Aims During peritoneal equilibrium test (PET), intermediate measures of Dt/P (dialysate/plasma creatinine ratio), D0/P, D2/P and D4/P ratios might provide additional information regarding a patient’s cardiovascular mortality. We aimed to... Read More about Dialysate Creatinine Response Patterns During Peritoneal Equilibration Test and the Association Between Cardiovascular Mortality: Findings from a Prospective Cohort Study..

Development and validation of risk prediction models for cardiovascular mortality in Chinese people initialising peritoneal dialysis: a cohort study (2018)
Journal Article
Yu. (2018). Development and validation of risk prediction models for cardiovascular mortality in Chinese people initialising peritoneal dialysis: a cohort study. Scientific reports, https://doi.org/10.1038/s41598-018-20160-3

Cardiovascular disease is the leading cause of death among patients receiving peritoneal dialysis. We aimed to develop and validate a risk prediction model for cardiovascular death within 2 years after the initiation of peritoneal dialysis (PD). A co... Read More about Development and validation of risk prediction models for cardiovascular mortality in Chinese people initialising peritoneal dialysis: a cohort study.

Population-level impact of diabetes integrated care on commissioner payments for inpatient care among people with type 2 diabetes in Cambridgeshire: a postintervention cohort follow-up study (2017)
Journal Article
Yu. (2017). Population-level impact of diabetes integrated care on commissioner payments for inpatient care among people with type 2 diabetes in Cambridgeshire: a postintervention cohort follow-up study. BMJ Open, https://doi.org/10.1136/bmjopen-2017-015816

Objectives Few studies have estimated the effect of diabetes integrated care at a population level. We have assessed the impact of introducing a community service-led diabetes integrated care programme on commissioner payments (tariff) for inpatient... Read More about Population-level impact of diabetes integrated care on commissioner payments for inpatient care among people with type 2 diabetes in Cambridgeshire: a postintervention cohort follow-up study.

Population trends in the incidence and initial management of osteoarthritis: age-period-cohort analysis of the Clinical Practice Research Datalink, 1992–2013 (2017)
Journal Article
Yu, D., Jordan, K., Bedson, J., Englund, M., Blyth, F., Turkiewicz, A., …Peat, G. (2017). Population trends in the incidence and initial management of osteoarthritis: age-period-cohort analysis of the Clinical Practice Research Datalink, 1992–2013. Rheumatology, 56(11), 1902-1917. https://doi.org/10.1093/rheumatology/kex270

Objective To determine recent trends in the rate and management of new cases of OA presenting to primary healthcare using UK nationally representative data. Methods Using the Clinical Practice Research Datalink we identified new cases of diagnos... Read More about Population trends in the incidence and initial management of osteoarthritis: age-period-cohort analysis of the Clinical Practice Research Datalink, 1992–2013.

IL-6 promotes epithelial-to-mesenchymal transition of human peritoneal mesothelial cells possibly through the JAK2/STAT3 signaling pathway. (2017)
Journal Article
Yu. (2017). IL-6 promotes epithelial-to-mesenchymal transition of human peritoneal mesothelial cells possibly through the JAK2/STAT3 signaling pathway. American journal of physiology. Renal physiology, F310 - F318. https://doi.org/10.1152/ajprenal.00428.2016

Long-term peritoneal dialysis (PD) therapy results in functional and structural alteration of the peritoneal membrane, including epithelial-to-mesenchymal transition (EMT). Interleukin 6 (IL-6) is a local pleiotropic cytokine, hypothesized to play an... Read More about IL-6 promotes epithelial-to-mesenchymal transition of human peritoneal mesothelial cells possibly through the JAK2/STAT3 signaling pathway..

Potential health impact and cost-effectiveness of drug therapy for prehypertension (2017)
Journal Article
Yu. (2017). Potential health impact and cost-effectiveness of drug therapy for prehypertension. International Journal of Cardiology, 403-408. https://doi.org/10.1016/j.ijcard.2017.05.003

Background Studies have reported that pharmacologic interventions with candesartan or ramipril could reduce the risk of hypertension among prehypertensive subjects free of clinical cardiovascular disease (CVD), however, the cost-effectiveness and lo... Read More about Potential health impact and cost-effectiveness of drug therapy for prehypertension.

Association between pulmonary function and renal function: findings from China and Australia. (2017)
Journal Article
Yu. (2017). Association between pulmonary function and renal function: findings from China and Australia. BMC Nephrology, https://doi.org/10.1186/s12882-017-0565-y

Background The relationship between obstructive lung function and impaired renal function is unclear. This study investigated the dose-response relationship between obstructive lung function and impaired renal function. Methods Two independent c... Read More about Association between pulmonary function and renal function: findings from China and Australia..

Accuracy of glomerular filtration rate equations for chronic kidney disease patients at the G3a stage: a single-center cross-sectional study (2017)
Journal Article
Dou, Y., Sun, X., Liu, D., Zhang, L., Xiao, J., Cheng, G., …Zhao, Z. (2017). Accuracy of glomerular filtration rate equations for chronic kidney disease patients at the G3a stage: a single-center cross-sectional study. BMC Research Notes, 10, Article 107. https://doi.org/10.1186/s13104-017-2400-8

Background Kidney disease improving global outcomes provided a new classification for chronic kidney disease (CKD) by subdividing the G3 stage into G3a and G3b stages based on glomerular filtration rate (GFR) in 2012. Currently, a few methods are us... Read More about Accuracy of glomerular filtration rate equations for chronic kidney disease patients at the G3a stage: a single-center cross-sectional study.

Interaction between Mean Arterial Pressure and HbA1c in Prediction of Cardiovascular Disease Hospitalisation: A Population-Based Case-Control Study (2016)
Journal Article
Yu. (2016). Interaction between Mean Arterial Pressure and HbA1c in Prediction of Cardiovascular Disease Hospitalisation: A Population-Based Case-Control Study. Journal of Diabetes Research, 1-7. https://doi.org/10.1155/2016/8714745

Objective. To explore the relationship between mean arterial pressure (MAP), HbA1c, and cardiovascular (CV) hospitalisation risk in type 2 diabetes. Design. Population-based case-control study. Settings. Primary and secondary care level in Ca... Read More about Interaction between Mean Arterial Pressure and HbA1c in Prediction of Cardiovascular Disease Hospitalisation: A Population-Based Case-Control Study.

Weighted cumulative exposure models helped identify an association between early knee-pain consultations and future knee OA diagnosis (2016)
Journal Article
Yu, D., Peat, G., Bedson, J., Edwards, J. J., Turkiewicz, A., & Jordan, K. P. (2016). Weighted cumulative exposure models helped identify an association between early knee-pain consultations and future knee OA diagnosis. Journal of Clinical Epidemiology, 218-228. https://doi.org/10.1016/j.jclinepi.2016.02.025

Objective To establish the association between prior knee-pain consultations and early diagnosis of knee osteoarthritis (OA) by weighted cumulative exposure (WCE) models. Study Design and Setting Data were from an electronic health care record (... Read More about Weighted cumulative exposure models helped identify an association between early knee-pain consultations and future knee OA diagnosis.

Association between pulse pressure and risk of hospital admissions for cardiovascular events among people with Type 2 diabetes: a population-based case-control study (2015)
Journal Article
Yu. (2015). Association between pulse pressure and risk of hospital admissions for cardiovascular events among people with Type 2 diabetes: a population-based case-control study. Diabetic Medicine, 1201 -1206. https://doi.org/10.1111/dme.12693

AIM: To investigate the association between pulse pressure and risk of hospitalization for cardiovascular events among people with Type 2 diabetes. METHODS: A population-based case-control study was carried out using data from medical databases. A to... Read More about Association between pulse pressure and risk of hospital admissions for cardiovascular events among people with Type 2 diabetes: a population-based case-control study.

Annual consultation incidence of osteoarthritis estimated from population-based health care data in England (2015)
Journal Article
Yu, D., Peat, G., Bedson, J., & Jordan, K. P. (2015). Annual consultation incidence of osteoarthritis estimated from population-based health care data in England. Rheumatology, 54(11), 2051-2060. https://doi.org/10.1093/rheumatology/kev231

OBJECTIVES: To estimate the consultation incidence of OA using population-based health care data in England and compare OA incidence figures with those derived in other countries. METHODS: A population-based health care database (Consultations in Pri... Read More about Annual consultation incidence of osteoarthritis estimated from population-based health care data in England.

Hospitalization among patients with diabetes associated with a Diabetes Integrated Care Initiative: a mixed methods case study (2015)
Journal Article
Simmons, D., Yu, D., Bunn, C., Cohn, S., Wenzel, H., & Prevost, T. (2015). Hospitalization among patients with diabetes associated with a Diabetes Integrated Care Initiative: a mixed methods case study. Future Hospital Journal, 2(2), 92-98. https://doi.org/10.7861/futurehosp.2-2-92

Integrated care has been postulated to result in improvements to diabetes outcomes, including reduced hospitalisation. The Diabetes Integrated Care Initiative (DICI) aimed to integrate primary, secondary and community diabetes care in East Cambridges... Read More about Hospitalization among patients with diabetes associated with a Diabetes Integrated Care Initiative: a mixed methods case study.

Hospitalisation among patients with diabetes associated with a Diabetes Integrated Care Initiative: a mixed methods case study (2015)
Journal Article
Yu. (2015). Hospitalisation among patients with diabetes associated with a Diabetes Integrated Care Initiative: a mixed methods case study. Future Hospital Journal, 92 - 98 (7). https://doi.org/10.7861/futurehosp.2-2-92

Integrated care has been postulated to result in improvements to diabetes outcomes, including reduced hospitalisation. The Diabetes Integrated Care Initiative (DICI) aimed to integrate primary, secondary and community diabetes care in East Cambridges... Read More about Hospitalisation among patients with diabetes associated with a Diabetes Integrated Care Initiative: a mixed methods case study.

45. Annual Consultation Incidence of Osteoarthritis Using Population-Based Healthcare Data in England (2014)
Journal Article
Yu, D., Peat, G., & Jordan, K. (2014). 45. Annual Consultation Incidence of Osteoarthritis Using Population-Based Healthcare Data in England. Rheumatology, 53(suppl_1), i72-i72. https://doi.org/10.1093/rheumatology/keu097.013

Background: OA poses a major challenge to population health and healthcare services. Unlike several other countries, there are no published estimates of the consultation incidence of OA based on population-based health care data in England. Method... Read More about 45. Annual Consultation Incidence of Osteoarthritis Using Population-Based Healthcare Data in England.

Concentration–Response Function for Ozone and Daily Mortality: Results from Five Urban and Five Rural U.K. Populations (2012)
Journal Article
Atkinson, R. W., Yu, D., Armstrong, B. G., Pattenden, S., Wilkinson, P., Doherty, R. M., …Anderson, H. R. (2012). Concentration–Response Function for Ozone and Daily Mortality: Results from Five Urban and Five Rural U.K. Populations. Environmental Health Perspectives, 120(10),

Background: Short-term exposure to ozone has been associated with increased daily mortality. The shape of the concentration–response relationship—and, in particular, if there is a threshold—is critical for estimating public health impacts. Objecti... Read More about Concentration–Response Function for Ozone and Daily Mortality: Results from Five Urban and Five Rural U.K. Populations.

Combined effects of smoking and systolic blood pressure on risk of coronary heart disease: a cohort study in Chinese women (2010)
Journal Article
Sun, D., Cao, J., Liu, X., Yu, L., Yao, C., Li, J., …Gu, D. (2010). Combined effects of smoking and systolic blood pressure on risk of coronary heart disease: a cohort study in Chinese women. Journal of Women's Health, 19(4), https://doi.org/10.1089/jwh.2009.1486

Objectives: To quantify the combined effects of systolic blood pressure (SBP) and cigarette smoking on incident coronary heart disease (CHD) in women. Methods: Overall, 86,338 women aged ≥40 years were enrolled in 1991. The follow-up evaluation wa... Read More about Combined effects of smoking and systolic blood pressure on risk of coronary heart disease: a cohort study in Chinese women.