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Remnant cholesterol and cardiovascular mortality in patients with type 2 diabetes and incident diabetic nephropathy (2021)
Journal Article
Qu, B., Zhang, X., Yu, D., Wang, Z., Cai, Y., Ma, S., …Simmons, D. (2021). Remnant cholesterol and cardiovascular mortality in patients with type 2 diabetes and incident diabetic nephropathy. Journal of Clinical Endocrinology and Metabolism, 3546-3553. https://doi.org/10.1210/clinem/dgab533

Context
The association between remnant cholesterol (remnant-C) and cardiovascular mortality in patients with type 2 diabetes (T2D) and incident diabetic nephropathy remains unclear.

Objective
To examinie the association between remnant-C and ca... Read More about Remnant cholesterol and cardiovascular mortality in patients with type 2 diabetes and incident diabetic nephropathy.

Investigating outcome inequalities in osteoarthritis management programmes: an analysis of registry data from the good life with osteoarthritis in Denmark (GLA:D®) programme using tapered balancing (2021)
Journal Article
Peat, G., Yu, D., Grønne, D., Marshall, M., Skou, S., & Roos, E. (2021). Investigating outcome inequalities in osteoarthritis management programmes: an analysis of registry data from the good life with osteoarthritis in Denmark (GLA:D®) programme using tapered balancing. Osteoarthritis and Cartilage, 29(S1), S376. https://doi.org/10.1016/j.joca.2021.02.489

Purpose: The burden of osteoarthritis (OA) is often greater among disadvantaged people and communities, prompting calls for more attention to equity-focussed research and policy. A specific concern is whether healthcare interventions may inadvertentl... Read More about Investigating outcome inequalities in osteoarthritis management programmes: an analysis of registry data from the good life with osteoarthritis in Denmark (GLA:D®) programme using tapered balancing.

Physical activity and fasting glucose in adults with abnormal glucose metabolism: Findings from two independent cross-sectional studies in China (2021)
Journal Article
Lu, L., Chen, Y., Cai, Y., Chen, T., Huang, Y., Meng, H., & Yu, D. (2021). Physical activity and fasting glucose in adults with abnormal glucose metabolism: Findings from two independent cross-sectional studies in China. Obesity Research and Clinical Practice, 15(3), 216-220. https://doi.org/10.1016/j.orcp.2021.03.011

Background
Relationship between physical activity and fasting glucose in people with abnormal glucose metabolism is not well-known. This study was to investigate dose–response association between physical activity (PAT) and fasting glucose from two... Read More about Physical activity and fasting glucose in adults with abnormal glucose metabolism: Findings from two independent cross-sectional studies in China.

Applicability and cost-effectiveness of the Systolic Blood Pressure Intervention Trial (SPRINT) in the Chinese population: A cost-effectiveness modeling study (2021)
Journal Article
Chen, T., Wu, Z., Wang, D., Yang, X., Yuan, X., Qin, R., …Wang, Y. (2021). Applicability and cost-effectiveness of the Systolic Blood Pressure Intervention Trial (SPRINT) in the Chinese population: A cost-effectiveness modeling study. PLoS Medicine, 18(3), https://doi.org/10.1371/journal.pmed.1003515

BACKGROUND: The Systolic Blood Pressure Intervention Trial (SPRINT) showed significant reductions in death and cardiovascular disease (CVD) risk with a systolic blood pressure (SBP) goal of <120 mm Hg compared with a SBP goal of <140 mm Hg. Our study...

Prevalence of cardiovascular risk factors in osteoarthritis patients derived from primary care records: a systematic review of observational studies (2021)
Journal Article
Huang, X., Wilkie, R., Mamas, M., & Yu, D. (2021). Prevalence of cardiovascular risk factors in osteoarthritis patients derived from primary care records: a systematic review of observational studies. MedRxiv, https://doi.org/10.1101/2021.02.14.21251130v1

<h4>Background</h4> People with osteoarthritis are at a high risk of cardiovascular disease (CVD). Detecting CVD risk factors in this high-risk population will help to improve CVD outcomes. Primary care electronic health records (EHRs) provide opport... Read More about Prevalence of cardiovascular risk factors in osteoarthritis patients derived from primary care records: a systematic review of observational studies.

Estimating the population health burden of musculoskeletal conditions using primary care electronic health records (2021)
Journal Article
Yu, D., Peat, G., Jordan, K., Bailey, J., Prieto-Alhambra, D., Robinson, D., …Wilkie, R. (2021). Estimating the population health burden of musculoskeletal conditions using primary care electronic health records. Rheumatology, 60(10), 4832-4843. https://doi.org/10.1093/rheumatology/keab109

Objectives
Better indicators from affordable, sustainable data sources are needed to monitor population burden of musculoskeletal conditions. We propose five indicators of musculoskeletal health and assessed if routinely available primary care elect... Read More about Estimating the population health burden of musculoskeletal conditions using primary care electronic health records.

Ethnic inequity in diabetes outcomes-inaction in the face of need (2020)
Journal Article
McKree Jansen, R., Sundborn, G., Cutfield, R., Yu, D., & Simmons, D. (2020). Ethnic inequity in diabetes outcomes-inaction in the face of need. New Zealand Medical Journal, 133(1525),

Evaluation of a longstanding primary care audit and diabetes care support service (DCSS) programme was reported in a paper published in Lancet Global Health on 15 October 2020. The paper showed 24 years of health outcome inequity among people with ty... Read More about Ethnic inequity in diabetes outcomes-inaction in the face of need.

Co-prescription of gabapentinoids and opioids among adults with and without osteoarthritis in the United Kingdom between 1995 and 2017 (2020)
Journal Article
Yu, Appleyard, T., Cottrell, E., & Peat, G. (2021). Co-prescription of gabapentinoids and opioids among adults with and without osteoarthritis in the United Kingdom between 1995 and 2017. Rheumatology, 60(4), 1942-1950. https://doi.org/10.1093/rheumatology/keaa586

Objectives
To produce national and regional estimates and trends of gabapentinoid-opioid co-prescribing rates in patients with osteoarthritis, both in absolute terms and relative to matched controls without osteoarthritis.

Methods
Using the UK C... Read More about Co-prescription of gabapentinoids and opioids among adults with and without osteoarthritis in the United Kingdom between 1995 and 2017.

Ethnic differences in mortality and hospital admission rates between Maori, Pacific, and European New Zealanders with type 2 diabetes between 1994 and 2018: a retrospective, population-based, longitudinal cohort study (2020)
Journal Article
Yu, D., Zhao, Z., Osuagwu, U. L., Pickering, K., Baker, J., Cutfield, R., …Simmons, D. (2021). Ethnic differences in mortality and hospital admission rates between Maori, Pacific, and European New Zealanders with type 2 diabetes between 1994 and 2018: a retrospective, population-based, longitudinal cohort study. The Lancet Global Health, 9(2), e209-e217. https://doi.org/10.1016/S2214-109X%2820%2930412-5

Background
Type 2 diabetes affects Indigenous and non-European populations disproportionately, including in New Zealand, where long-term temporal trends in cause-specific clinical outcomes between Maori, Pacific, and European people remain unclear.... Read More about Ethnic differences in mortality and hospital admission rates between Maori, Pacific, and European New Zealanders with type 2 diabetes between 1994 and 2018: a retrospective, population-based, longitudinal cohort study.

Cardiovascular risks and bleeding with non-vitamin K antagonist oral anticoagulant versus warfarin in patients with type 2 diabetes: a tapered matching cohort study (2020)
Journal Article
Yu, D., Zhao, Z., & Simmons, D. (2020). Cardiovascular risks and bleeding with non-vitamin K antagonist oral anticoagulant versus warfarin in patients with type 2 diabetes: a tapered matching cohort study. Cardiovascular Diabetology, 19, Article 174. https://doi.org/10.1186/s12933-020-01152-y

Abstract

Background
We compared the risk of bleeding and cardiovascular disease (CVD) events between non-vitamin K antagonist oral anticoagulant (NOAC) and warfarin in people with type 2 diabetes (T2DM).

Methods
862 Incident NOAC users and 62... Read More about Cardiovascular risks and bleeding with non-vitamin K antagonist oral anticoagulant versus warfarin in patients with type 2 diabetes: a tapered matching cohort study.

SECULAR TRENDS IN SHOULDER SURGERY IN THE UK BETWEEN 2000-2018 (2020)
Presentation / Conference
Robinson, D., Craig, R., Lane, J., Andrew, A., Bailey, J., Yu, D., …Prieto-Alhambra, D. (2020, August). SECULAR TRENDS IN SHOULDER SURGERY IN THE UK BETWEEN 2000-2018. Poster presented at World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2020), Spain (virtual)

Objective: Recent RCTs have demonstrated little efficacy of certain shoulder surgeries. To investigate the trend in shoulder surgery incidence over time overall and by surgery type.

Methods: Data were obtained from UK primary care electronic healt... Read More about SECULAR TRENDS IN SHOULDER SURGERY IN THE UK BETWEEN 2000-2018.

Association between systolic blood pressure and cardiovascular inpatient cost moderated by peer-support intervention among type 2 diabetes: two cohorts study (2020)
Journal Article
Cai, Y., Graffy, J., Holman, D., Zhao, Z., Simmons, D., & Yu, D. (2021). Association between systolic blood pressure and cardiovascular inpatient cost moderated by peer-support intervention among type 2 diabetes: two cohorts study. Canadian Journal of Diabetes, 45(2), 179-185.e1. https://doi.org/10.1016/j.jcjd.2020.07.008

Objective
People with type 2 diabetes and increased systolic blood pressure (SBP) are at high risk of cardiovascular diseases (CVD). We aimed to investigate the association between CVD related hospital payments and SBP and test whether it is influen... Read More about Association between systolic blood pressure and cardiovascular inpatient cost moderated by peer-support intervention among type 2 diabetes: two cohorts study.

Derivation and validation of a risk score predicting early-onset risk of peritonitis among patients initialising peritoneal dialysis: a cohort study (2020)
Journal Article
Ma, S., Cai, Y., Wang, Z., Zhao, Z., Xiao, J., & Yu, D. (2020). Derivation and validation of a risk score predicting early-onset risk of peritonitis among patients initialising peritoneal dialysis: a cohort study. International Journal of Infectious Diseases, 99, 301-306. https://doi.org/10.1016/j.ijid.2020.08.009

Objectives
Early onset peritonitis (EOP) increases risk of clinical complications in patients initialising peritoneal dialysis (PD). This study aimed to develop and validate a risk prediction model for EOP among patients initialising PD.

Methods... Read More about Derivation and validation of a risk score predicting early-onset risk of peritonitis among patients initialising peritoneal dialysis: a cohort study.

Association between long-term pulse pressure trajectories and risk of end-stage renal diseases in incident malignant hypertensive nephropathy (2020)
Journal Article
Zhuang, Y., Ding, C., Xu, Y., Ding, Z., & Yu, D. (2020). Association between long-term pulse pressure trajectories and risk of end-stage renal diseases in incident malignant hypertensive nephropathy. Blood Pressure Monitoring, https://doi.org/10.1097/MBP.0000000000000477

Objective
The trajectories of pulse pressure (PP) might affect the prognosis of malignant hypertensive nephropathy (MHN). We aimed to describe the association between PP trajectories and the future risk of end-stage renal disease and to identify and... Read More about Association between long-term pulse pressure trajectories and risk of end-stage renal diseases in incident malignant hypertensive nephropathy.

Association between long-term pulse pressure trajectories and risk of end-stage renal diseases in incident malignant hypertensive nephropathy (2020)
Journal Article
Zhuang, Y., Ding, C., Xu, Y., Ding, Z., & Yu, D. (2021). Association between long-term pulse pressure trajectories and risk of end-stage renal diseases in incident malignant hypertensive nephropathy. Blood Pressure Monitoring, 26(1), 14-21. https://doi.org/10.1097/MBP.0000000000000477

Objective The trajectories of pulse pressure (PP) might affect the prognosis of malignant hypertensive nephropathy (MHN). We aimed to describe the association between PP trajectories and the future risk of end-stage renal disease and to identify and... Read More about Association between long-term pulse pressure trajectories and risk of end-stage renal diseases in incident malignant hypertensive nephropathy.

Physical activity and liver health among urban and rural Chinese adults: results from two independent surveys (2020)
Journal Article
Chen, Y., Chen, Y., Qin, R., Cai, Y., Bai, F., Yu, D., …Geng, B. (2021). Physical activity and liver health among urban and rural Chinese adults: results from two independent surveys. Journal of Exercise Science and Fitness, 19(1), 8-12. https://doi.org/10.1016/j.jesf.2020.07.004

Background
Increased physical activity has been associated with reduced risks of various physical and mental conditions. However, the association between physical activity and liver health in the Chinese general adult population is not clear. This s... Read More about Physical activity and liver health among urban and rural Chinese adults: results from two independent surveys.

Dose-response association between physical activity and clustering of modifiable cardiovascular risk factors among 26,093 Chinese adults (2020)
Journal Article
Shi, R., Cai, Y., Yang, Y., Yu, D., & Qin, R. (2020). Dose-response association between physical activity and clustering of modifiable cardiovascular risk factors among 26,093 Chinese adults. BMC Cardiovascular Disorders, 20, Article 347. https://doi.org/10.1186/s12872-020-01627-6

Background
There is uncertain evidence in the dose-response association between overall physical activity levels and clustering of cardiovascular diseases modifiable risk factors (CVDMRF) in Chinese adults. This study examined the hypothesis whether... Read More about Dose-response association between physical activity and clustering of modifiable cardiovascular risk factors among 26,093 Chinese adults.

THE DESCRIPTIVE EPIDEMIOLOGY AND SECULAR TRENDS OF LOWER BACK PAIN PROCEDURES IN ROUTINE UK NHS CARE FROM 2000 TO 2016 (2020)
Presentation / Conference
Robinson, D., Lane, J., Craig, R., Judge, A., Bailey, J., Yu, D., …Prieto-Alhambra, D. (2020, June). THE DESCRIPTIVE EPIDEMIOLOGY AND SECULAR TRENDS OF LOWER BACK PAIN PROCEDURES IN ROUTINE UK NHS CARE FROM 2000 TO 2016. Poster presented at EULAR 2020

Background: The lifetime prevalence of lower back pain is between 60% and 70%, with surgical treatments spared for those not responding to other options.

Objectives: To investigate the age, gender and socio-economic status differences in back pain... Read More about THE DESCRIPTIVE EPIDEMIOLOGY AND SECULAR TRENDS OF LOWER BACK PAIN PROCEDURES IN ROUTINE UK NHS CARE FROM 2000 TO 2016.

Dialysate glucose response phenotypes during peritoneal equilibration test and their association with cardiovascular death A cohort study (2020)
Journal Article
Wang, Z., Yu, D., Cai, Y., Ma, S., Zhao, B., Zhao, Z., & Simmons, D. (2020). Dialysate glucose response phenotypes during peritoneal equilibration test and their association with cardiovascular death A cohort study. Medicine, 99(21), e20447 - e20447. https://doi.org/10.1097/MD.0000000000020447

Different measures of rates of transfer of glucose during the peritoneal equilibrium test (PET), undertaken during peritoneal dialysis (PD) might provide additional information regarding a patient's risk of future cardiovascular mortality. This study... Read More about Dialysate glucose response phenotypes during peritoneal equilibration test and their association with cardiovascular death A cohort study.